Molecular mechanisms in gliomagenesis (Q36226724)

12 August 2017

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title

Molecular mechanisms in gliomagenesis (English)

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12 August 2017

2

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12 August 2017

Esther Hulleman

1

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12 August 2017

publication date

1 January 2005

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Advances in Cancer Research

12 August 2017

published in

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12 August 2017

volume

94

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12 August 2017

page(s)

1-27

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Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

12 August 2017

cites work

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7 January 2021

Binding of SH2 domains of phospholipase C gamma 1, GAP, and Src to activated growth factor receptors

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Phosphorylation of HDM2 by Akt.

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7 January 2021

Epidermal growth factor receptor and Ink4a/Arf

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7 January 2021

Classification of glioblastoma multiforme in adults by molecular genetics

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7 January 2021

PTEN/MMAC1/TEP1 in signal transduction and tumorigenesis

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7 January 2021

A functional polymorphism in the EGF gene is found with increased frequency in glioblastoma multiforme patients and is associated with more aggressive disease

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7 January 2021

Alterations of cell cycle regulatory genes in primary (de novo) and secondary glioblastomas

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https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

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7 January 2021

Constitutive EGFR signaling confers a motile phenotype to neural stem cells

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7 January 2021

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

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7 January 2021

Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor

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7 January 2021

Molecular genetic correlates of p16, cdk4, and pRb immunohistochemistry in glioblastomas

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7 January 2021

Response Diversity and the Timing of Progenitor Cell Maturation Are Regulated by Developmental Changes in EGFR Expression in the Cortex

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7 January 2021

Emerging roles for E2F: Beyond the G1/S transition and DNA replication

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7 January 2021

A tightly associated serine/threonine protein kinase regulates phosphoinositide 3-kinase activity

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7 January 2021

Gene expression patterns in human liver cancers

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7 January 2021

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

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7 January 2021

PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo

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7 January 2021

c-Myc target genes involved in cell growth, apoptosis, and metabolism

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7 January 2021

Cellular survival: a play in three Akts

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7 January 2021

PI 3-kinase is a dual specificity enzyme: autoregulation by an intrinsic protein-serine kinase activity.

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7 January 2021

Platelet-derived Growth Factor and Its Receptor Expression in Human Oligodendrogliomas

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7 January 2021

EGF converts transit-amplifying neurogenic precursors in the adult brain into multipotent stem cells

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7 January 2021

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Amoeboid microglia expressing GD3 ganglioside are concentrated in regions of oligodendrogenesis during development of the rat corpus callosum.

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Quantification of the c-myc oncoprotein in human glioblastoma cells and tumor tissue

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Smad2, Smad3 and Smad4 cooperate with Sp1 to induce p15(Ink4B) transcription in response to TGF-beta

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Cell cycle-dependent recruitment of HDAC-1 correlates with deacetylation of histone H4 on an Rb-E2F target promoter

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Transforming growth factor beta-mediated transcriptional repression of c-myc is dependent on direct binding of Smad3 to a novel repressive Smad binding element

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Control of apoptosis by p53.

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https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Deletion mapping of the long arm of chromosome 10 in glioblastoma multiforme

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https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

MYC expression promotes the proliferation of neural progenitor cells in culture and in vivo

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Molecular classification of cancer: class discovery and class prediction by gene expression monitoring

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Brain factor-1 controls the proliferation and differentiation of neocortical progenitor cells through independent mechanisms

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https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Foxg1 suppresses early cortical cell fate

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https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Chromatin remodeling and Rb activity

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https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Analysis of glioma cell lines for amplification and overexpression of MDM2.

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https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

The retinoblastoma gene is involved in malignant progression of astrocytomas

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Modeling mutations in the G1 arrest pathway in human gliomas: overexpression of CDK4 but not loss of INK4a-ARF induces hyperploidy in cultured mouse astrocytes

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Gliomagenesis: genetic alterations and mouse models

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https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Progenitor cells and glioma formation

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https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Astrocytes give rise to oligodendrogliomas and astrocytomas after gene transfer of polyoma virus middle T antigen in vivo

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https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Interaction of phosphatidylinositol 3-kinase-associated p85 with epidermal growth factor and platelet-derived growth factor receptors

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https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Astrocyte-specific expression of CDK4 is not sufficient for tumor formation, but cooperates with p53 heterozygosity to provide a growth advantage for astrocytes in vivo.

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro

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https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Homozygous deletions of p16INK4A/MTS1 and p15INK4B/MTS2 genes in glioma cells and primary glioma tissues.

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

The role of transforming growth factor beta in glioma progression

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https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

TGF beta 1 and TGF beta 2 are potential growth regulators for low-grade and malignant gliomas in vitro: evidence in support of an autocrine hypothesis

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Astroglial c-Myc overexpression predisposes mice to primary malignant gliomas

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

The WHO classification of tumors of the nervous system

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line

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https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Signaling pathways regulating gliomagenesis

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https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Direct control of the Forkhead transcription factor AFX by protein kinase B

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https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Quantitative real-time PCR does not show selective targeting of p14(ARF) but concomitant inactivation of both p16(INK4A) and p14(ARF) in 105 human primary gliomas.

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Pathways leading to glioblastoma multiforme: a molecular analysis of genetic alterations in 65 astrocytic tumors.

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

PTEN regulation of neural development and CNS stem cells

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Mutant epidermal growth factor receptor displays increased signaling through the phosphatidylinositol-3 kinase/AKT pathway and promotes radioresistance in cells of astrocytic origin

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https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Activation of extracellular-regulated kinases by normal and mutant EGF receptors

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Malignant glioma: genetics and biology of a grave matter.

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Expression of platelet-derived growth factor and transforming growth factor and their correlation with cellular morphology in glial tumors

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Differential gene expression profiling in human brain tumors

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https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

How cells read TGF-beta signals

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https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

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https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

The PTEN, Mdm2, p53 tumor suppressor-oncoprotein network

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https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

FGF modulates the PDGF-driven pathway of oligodendrocyte development.

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Identification of molecular subtypes of glioblastoma by gene expression profiling

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Recycling the Cell Cycle

1 reference

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7 January 2021

p14ARF deletion and methylation in genetic pathways to glioblastomas.

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity

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https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Contribution of stem cells and differentiated cells to epidermal tumours

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7 January 2021

Role of Smad proteins and transcription factor Sp1 in p21(Waf1/Cip1) regulation by transforming growth factor-beta.

1 reference

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7 January 2021

Expression of a naturally occurring constitutively active variant of the epidermal growth factor receptor in mouse fibroblasts increases motility

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7 January 2021

Stem-cell hierarchy in skin cancer

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7 January 2021

Molecular portraits of human breast tumours

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7 January 2021

Neural stem cells and neuro-oncology: quo vadis?

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7 January 2021

Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Transforming growth factor-beta-mediated p15(INK4B) induction and growth inhibition in astrocytes is SMAD3-dependent and a pathway prominently altered in human glioma cell lines

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

A role for platelet-derived growth factor in normal gliogenesis in the central nervous system

1 reference

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7 January 2021

Transforming growth factor-beta1 up-regulates p15, p21 and p27 and blocks cell cycling in G1 in human prostate epithelium

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7 January 2021

The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

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7 January 2021

TGFbeta influences Myc, Miz-1 and Smad to control the CDK inhibitor p15INK4b

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7 January 2021

Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation

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7 January 2021

Role of the INK4a locus in tumor suppression and cell mortality.

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7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Gene expression profiling identifies molecular subtypes of gliomas

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

CDK inhibitors: positive and negative regulators of G1-phase progression

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https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

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https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

A revised picture of the E2F transcriptional network and RB function

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Protein expression of Fas, Fas ligand, Bcl-2 and TGFbeta2 and correlation with survival in initial and recurrent human gliomas

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7 January 2021

Function of aberrant EGFR in malignant gliomas

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7 January 2021

Cdk-mediated phosphorylation of pRB regulates HDAC binding in vitro

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

The development of neural stem cells

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Evidence for rearrangement, amplification, and expression of c-myc in a human glioblastoma

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Expression of fibroblast growth factor receptor-1 in human glioma and meningioma tissues

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Modeling gliomagenesis with somatic cell gene transfer using retroviral vectors

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Characterization of gene expression profiles associated with glioma progression using oligonucleotide-based microarray analysis and real-time reverse transcription-polymerase chain reaction

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Growth factor profiles of human gliomas. Do non-tumour cells contribute to tumour growth in glioma?

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Gene expression profiling predicts clinical outcome of breast cancer

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Live or let die: the cell's response to p53

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Astrocyte inactivation of the pRb pathway predisposes mice to malignant astrocytoma development that is accelerated by PTEN mutation

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Winged helix transcription factor BF-1 is essential for the development of the cerebral hemispheres

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

c-myc is a downstream target of the Smad pathway

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Enhanced expression of transforming growth factor‐β and its type‐I and type‐II receptors in human glioblastoma

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Expression of p27KIP1 in human gliomas: relationship between tumor grade, proliferation index, and patient survival

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Decision making by p53: life, death and cancer

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

1 reference

https://api.crossref.org/works/10.1016/S0065-230X(05)94001-3

7 January 2021

10.1016/S0065-230X(05)94001-3

Identifiers

DOI

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12 August 2017

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