Phosphatidic acid mediates the targeting of tBid to induce lysosomal membrane permeabilization and apoptosis (Q36213869)

12 August 2017

Phosphatidic acid mediates the targeting of tBid to induce lysosomal membrane permeabilization and apoptosis (English)

1 reference

12 August 2017

Kai Zhao

1

1 reference

12 August 2017

Hejiang Zhou

2

1 reference

12 August 2017

Xingyu Zhao

3

1 reference

12 August 2017

Dennis W Wolff

4

1 reference

12 August 2017

Yaping Tu

5

1 reference

12 August 2017

Huili Liu

6

1 reference

12 August 2017

Taotao Wei

7

1 reference

12 August 2017

Fuyu Yang

8

1 reference

12 August 2017

3 July 2012

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Journal of Lipid Research

12 August 2017

1 reference

12 August 2017

53

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12 August 2017

10

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12 August 2017

2102-2114

1 reference

Putting the pH into phosphatidic acid signaling

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Cell death by autophagy: facts and apparent artefacts

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Lysosomes and lysosomal cathepsins in cell death

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

A lipocentric view of peptide-induced pores.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Mitochondria and cell death: outer membrane permeabilization and beyond

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Pathophysiological functions of cathepsin D: Targeting its catalytic activity versus its protein binding activity?

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Mechanistic issues of the interaction of the hairpin-forming domain of tBid with mitochondrial cardiolipin

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Oligomerization of membrane-bound Bcl-2 is involved in its pore formation induced by tBid

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Biophysics and function of phosphatidic acid: a molecular perspective

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Phosphatidic acid signaling to mTOR: signals for the survival of human cancer cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Mitochondrial outer membrane proteins assist Bid in Bax-mediated lipidic pore formation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Membrane binding by tBid initiates an ordered series of events culminating in membrane permeabilization by Bax

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Structure of transmembrane pore induced by Bax-derived peptide: evidence for lipidic pores.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Lysosomal membrane permeabilization in cell death

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Mitochondrial dysfunction and oxidative stress in the pathogenesis of alcohol- and obesity-induced fatty liver diseases

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Chymotrypsin B cached in rat liver lysosomes and involved in apoptotic regulation through a mitochondrial pathway

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Autophagy: process and function

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Functions and dysfunctions of mitochondrial dynamics

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Embedded together: the life and death consequences of interaction of the Bcl-2 family with membranes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Cell death modalities: classification and pathophysiological implications

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Phosphatidic acid- and phosphatidylserine-binding proteins

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Spontaneous curvature of phosphatidic acid and lysophosphatidic acid.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Nonbilayer lipids affect peripheral and integral membrane proteins via changes in the lateral pressure profile.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Conformation of membrane-associated proapoptotic tBid

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

1 October 2017

Lysosomes in cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Modulation of membrane curvature by phosphatidic acid and lysophosphatidic acid

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Regulators of G-protein signaling (RGS) 4, insertion into model membranes and inhibition of activity by phosphatidic acid

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Susceptibility of lysosomes to rupture is a determinant for plasma membrane disruption in tumor necrosis factor alpha-induced cell death

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

tBID Homooligomerizes in the mitochondrial membrane to induce apoptosis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Phosphatidic acid-mediated mitogenic activation of mTOR signaling

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Leakage and aggregation of phospholipid vesicles induced by the BH3-only Bcl-2 family member, BID.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Structure of Bax: coregulation of dimer formation and intracellular localization

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Solution structure of BID, an intracellular amplifier of apoptotic signaling

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Developmental cell death: morphological diversity and multiple mechanisms

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Phospholipase D2-generated phosphatidic acid couples EGFR stimulation to Ras activation by Sos.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

tBid elicits a conformational alteration in membrane-bound Bcl-2 such that it inhibits Bax pore formation

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435543

Lysosomal chymotrypsin B potentiates apoptosis via cleavage of Bid.

29 June 2018

1 reference

tBid forms a pore in the liposome membrane

21 January 2018

1 reference

The interaction between tBid and cardiolipin or monolysocardiolipin

21 January 2018

1 reference

The apoptotic protein tBid promotes leakage by altering membrane curvature

21 January 2018

1 reference

The recruitment of Raf-1 to membranes is mediated by direct interaction with phosphatidic acid and is independent of association with Ras.

21 January 2018

1 reference

What makes the bioactive lipids phosphatidic acid and lysophosphatidic acid so special?

21 January 2018

1 reference

tBid interaction with cardiolipin primarily orchestrates mitochondrial dysfunctions and subsequently activates Bax and Bak.

21 January 2018

1 reference

Membrane promotes tBID interaction with BCL(XL).

21 January 2018

1 reference

Interaction of the alpha-helical H6 peptide from the pro-apoptotic protein tBid with cardiolipin

21 January 2018

1 reference

Monte Carlo simulations of tBid association with the mitochondrial outer membrane

21 January 2018

1 reference

Lipidic pore formation by the concerted action of proapoptotic BAX and tBID.

21 January 2018

1 reference

The Destabilization of Lipid Membranes Induced by the C-terminal Fragment of Caspase 8-cleaved Bid Is Inhibited by the N-terminal Fragment

21 January 2018

1 reference

12 December 2020

Helix 6 of tBid is necessary but not sufficient for mitochondrial binding activity

1 reference

12 December 2020

Membrane-insertion fragments of Bcl-xL, Bax, and Bid

1 reference

12 December 2020

Cardiolipin provides specificity for targeting of tBid to mitochondria

1 reference

12 December 2020

Identifiers

DOI

10.1194/JLR.M027557

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

22761256

1 reference