Regulation of cell migration by sphingomyelin synthases: sphingomyelin in lipid rafts decreases responsiveness to signaling by the CXCL12/CXCR4 pathway. (Q36211046)

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English	Regulation of cell migration by sphingomyelin synthases: sphingomyelin in lipid rafts decreases responsiveness to signaling by the CXCL12/CXCR4 pathway.	scientific article

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4 February 2020

Regulation of cell migration by sphingomyelin synthases: sphingomyelin in lipid rafts decreases responsiveness to signaling by the CXCL12/CXCR4 pathway (English)

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4 February 2020

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Kazuyuki Kitatani

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4 February 2020

Makoto Taniguchi

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4 February 2020

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Satoshi Asano

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Mayumi Hashimoto

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Kota Zama

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Susumu Mitsutake

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Yasuyuki Igarashi

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Hiroyuki Takeya

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Junzo Kigawa

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Akira Hayashi

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Hisanori Umehara

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Toshiro Okazaki

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11 June 2012

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4 February 2020

Molecular and Cellular Biology

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4 February 2020

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3242-3252

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4 February 2020

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11 June 2022

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Sphingomyelin Synthase 1-generated Sphingomyelin Plays an Important Role in Transferrin Trafficking and Cell Proliferation

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1 October 2017

Dynamic modification of sphingomyelin in lipid microdomains controls development of obesity, fatty liver, and type 2 diabetes

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1 October 2017

Mitochondrial dysfunction and increased reactive oxygen species impair insulin secretion in sphingomyelin synthase 1-null mice

1 reference

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Nanoliposomal short-chain ceramide inhibits agonist-dependent translocation of neurotensin receptor 1 to structured membrane microdomains in breast cancer cells

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1 October 2017

Fluorescence resonance energy transfer imaging reveals that chemokine-binding modulates heterodimers of CXCR4 and CCR5 receptors

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1 October 2017

Impaired TCR signaling through dysfunction of lipid rafts in sphingomyelin synthase 1 (SMS1)-knockdown T cells

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1 October 2017

Regulation of neural progenitor cell motility by ceramide and potential implications for mouse brain development

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1 October 2017

CXCR4 dimerization and beta-arrestin-mediated signaling account for the enhanced chemotaxis to CXCL12 in WHIM syndrome.

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1 October 2017

Decreased ceramide transport protein (CERT) function alters sphingomyelin production following UVB irradiation

1 reference

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1 October 2017

Suppression of sphingomyelin synthase 1 by small interference RNA is associated with enhanced ceramide production and apoptosis after photodamage

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1 October 2017

Principles of bioactive lipid signalling: lessons from sphingolipids

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1 October 2017

SMS overexpression and knockdown: impact on cellular sphingomyelin and diacylglycerol metabolism, and cell apoptosis.

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1 October 2017

Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7

1 reference

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1 October 2017

Inhibition of sphingomyelin synthase (SMS) affects intracellular sphingomyelin accumulation and plasma membrane lipid organization

1 reference

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1 October 2017

Evidence for a role of glycosphingolipids in CXCR4-dependent cell migration

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1 October 2017

Sphingomyelin synthase 1 suppresses ceramide production and apoptosis post-photodamage

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1 October 2017

Both sphingomyelin synthases SMS1 and SMS2 are required for sphingomyelin homeostasis and growth in human HeLa cells

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1 October 2017

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1 October 2017

Dimerization of CXCR4 in living malignant cells: control of cell migration by a synthetic peptide that reduces homologous CXCR4 interactions

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1 October 2017

A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development

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1 October 2017

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1 October 2017

Role of the CXCL12/CXCR4 axis in peritoneal carcinomatosis of gastric cancer

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1 October 2017

CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment

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1 October 2017

The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes

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Silencing of CXCR4 blocks breast cancer metastasis

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Bioluminescence resonance energy transfer reveals ligand-induced conformational changes in CXCR4 homo- and heterodimers.

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1 October 2017

Novel clusters of receptors for sphingosine-1-phosphate, sphingosylphosphorylcholine, and (lyso)-phosphatidic acid: new receptors for "old" ligands

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Inhibition of breast cancer metastasis by selective synthetic polypeptide against CXCR4.

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1 October 2017

Lipid rafts and plasma membrane microorganization: insights from Ras.

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1 October 2017

Expression cloning of a human cDNA restoring sphingomyelin synthesis and cell growth in sphingomyelin synthase-defective lymphoid cells

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1 October 2017

Identification of a family of animal sphingomyelin synthases

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1 October 2017

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

Structure and function of membrane rafts

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1 October 2017

Lipid rafts and signal transduction

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1 October 2017

The chemokine SDF-1alpha triggers CXCR4 receptor dimerization and activates the JAK/STAT pathway

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1 October 2017

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1 October 2017

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1 October 2017

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22 September 2018

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22 September 2018

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5 December 2018

Chemokine receptors

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12 December 2020

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Metabotropic glutamate receptor 5 is a disulfide-linked dimer

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12 December 2020

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4 February 2020

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4 February 2020

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4 February 2020

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