Suppressors of superoxide production from mitochondrial complex III (Q36200360)

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24 February 2020

title

Suppressors of superoxide production from mitochondrial complex III (English)

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10

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Martin D. Brand

15

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3

Carolina N Turk

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Irina V. Perevoshchikova

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object named as

Irina V Perevoshchikova

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author name string

Adam L Orr

1

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24 February 2020

Leonardo Vargas

2

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Janine E Baaten

4

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Jason T Matzen

5

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Victoria J Dardov

6

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Stephen J Attle

7

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Jing Li

8

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Douglas C Quackenbush

9

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H Michael Petrassi

12

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Shelly L Meeusen

13

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Edward K Ainscow

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publication date

14 September 2015

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24 February 2020

published in

Nature Chemical Biology

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volume

11

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24 February 2020

issue

11

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24 February 2020

page(s)

834-836

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Novel inhibitors of mitochondrial sn-glycerol 3-phosphate dehydrogenase.

24 February 2020

cites work

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Sites of reactive oxygen species generation by mitochondria oxidizing different substrates

1 October 2017

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The determination and analysis of site-specific rates of mitochondrial reactive oxygen species production

1 October 2017

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Validation of a HTS-amenable assay to detect drug-induced mitochondrial toxicity in the absence and presence of cell death

1 October 2017

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1 October 2017

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Mitochondria are required for antigen-specific T cell activation through reactive oxygen species signaling.

1 October 2017

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The role of mitochondrial dehydrogenases in the generation of oxidative stress.

1 October 2017

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Differential effects of complex II on mitochondrial ROS production and their relation to cardioprotective pre- and postconditioning

1 October 2017

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Superoxide generation by complex III: from mechanistic rationales to functional consequences

1 October 2017

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T cell activation is driven by an ADP-dependent glucokinase linking enhanced glycolysis with mitochondrial reactive oxygen species generation

1 October 2017

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Physiological roles of mitochondrial reactive oxygen species

1 October 2017

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Mitochondrial complex II can generate reactive oxygen species at high rates in both the forward and reverse reactions

1 October 2017

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High throughput microplate respiratory measurements using minimal quantities of isolated mitochondria

1 October 2017

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The mechanism of superoxide production by the antimycin-inhibited mitochondrial Q-cycle

1 October 2017

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Mitochondrial c-Jun N-terminal kinase (JNK) signaling initiates physiological changes resulting in amplification of reactive oxygen species generation.

1 October 2017

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Inhibition of respiration extends C. elegans life span via reactive oxygen species that increase HIF-1 activity

1 October 2017

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Stabilization of hypoxia-inducible factor-1alpha protein in hypoxia occurs independently of mitochondrial reactive oxygen species production.

1 October 2017

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Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity

1 October 2017

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Terpestacin inhibits tumor angiogenesis by targeting UQCRB of mitochondrial complex III and suppressing hypoxia-induced reactive oxygen species production and cellular oxygen sensing

1 October 2017

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Mitochondrial complex III-generated oxidants activate ASK1 and JNK to induce alveolar epithelial cell death following exposure to particulate matter air pollution

1 October 2017

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1 October 2017

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1 October 2017

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A mutation in the SDHC gene of complex II increases oxidative stress, resulting in apoptosis and tumorigenesis.

1 October 2017

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Mechanism of toxicity in rotenone models of Parkinson's disease

1 October 2017

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1 October 2017

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1 October 2017

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Qo site of mitochondrial complex III is the source of increased superoxide after transient exposure to hydrogen peroxide.

2 July 2018

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Low complex I content explains the low hydrogen peroxide production rate of heart mitochondria from the long-lived pigeon, Columba livia

22 September 2018

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Critical role of complex III in the early metabolic changes following myocardial infarction

22 September 2018

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22 September 2018

Identifiers

DOI

10.1038/NCHEMBIO.1910

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24 February 2020

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24 February 2020

PubMed publication ID

26368590

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