Glycan modulation and sulfoengineering of anti-HIV-1 monoclonal antibody PG9 in plants. (Q36179265)

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25 February 2020

title

Glycan modulation and sulfoengineering of anti-HIV-1 monoclonal antibody PG9 in plants (English)

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1 reference

2

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Duc Bui Minh

7

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25 February 2020

Gordana Wozniak Knopp

9

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Friedrich Altmann

11

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Herta Steinkellner

12

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Lukas Mach

13

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10

Donald N Forthal

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author name string

Andreas Loos

1

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25 February 2020

Thomas Hackl

3

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25 February 2020

Daniel Maresch

4

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Theresa Henkel

5

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25 February 2020

Andreas Porodko

6

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25 February 2020

Wolfgang Sommeregger

8

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25 February 2020

language of work or name

English

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publication date

28 September 2015

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Proceedings of the National Academy of Sciences of the United States of America

25 February 2020

number of pages

6

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based on heuristic

inferred from page(s)

published in

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volume

112

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25 February 2020

issue

41

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25 February 2020

page(s)

12675-12680

1 reference

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Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117.

25 February 2020

cites work

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1 October 2017

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Plant glyco-biotechnology on the way to synthetic biology

1 October 2017

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1 October 2017

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Tyrosine sulfation in the second variable loop (V2) of HIV-1 gp120 stabilizes V2-V3 interaction and modulates neutralization sensitivity

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Qualitative and quantitative variables that affect the potency of Fc- mediated effector function in vitro and in vivo: considerations for passive immunization using non-neutralizing antibodies

1 October 2017

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1 October 2017

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A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies

1 October 2017

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A human antibody to the CD4 binding site of gp120 capable of highly potent but sporadic cross clade neutralization of primary HIV-1.

1 October 2017

1 reference

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Glycosylation and functionality of recombinant β-glucocerebrosidase from various production systems

1 October 2017

1 reference

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Synthetic glycopeptides reveal the glycan specificity of HIV-neutralizing antibodies.

1 October 2017

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Structural basis for diverse N-glycan recognition by HIV-1–neutralizing V1–V2–directed antibody PG16

1 October 2017

1 reference

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Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9.

1 October 2017

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HIV therapy by a combination of broadly neutralizing antibodies in humanized mice.

1 October 2017

1 reference

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A draft genome sequence of Nicotiana benthamiana to enhance molecular plant-microbe biology research

1 October 2017

1 reference

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The future of antibodies as cancer drugs

1 October 2017

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Isotype and glycoform selection for antibody therapeutics

1 October 2017

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A nonfucosylated variant of the anti-HIV-1 monoclonal antibody b12 has enhanced FcγRIIIa-mediated antiviral activity in vitro but does not improve protection against mucosal SHIV challenge in macaques

1 October 2017

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Enhanced potency of a fucose-free monoclonal antibody being developed as an Ebola virus immunoprotectant

1 October 2017

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Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

1 October 2017

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Antibody-Mediated Fcγ Receptor-Based Mechanisms of HIV Inhibition: Recent Findings and New Vaccination Strategies

1 October 2017

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Pivotal trial with plant cell-expressed recombinant glucocerebrosidase, taliglucerase alfa, a novel enzyme replacement therapy for Gaucher disease

1 October 2017

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Broad neutralization coverage of HIV by multiple highly potent antibodies

1 October 2017

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Fc-glycosylation influences Fcγ receptor binding and cell-mediated anti-HIV activity of monoclonal antibody 2G12.

1 October 2017

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Crystal Structure of PG16 and Chimeric Dissection with Somatically Related PG9: Structure-Function Analysis of Two Quaternary-Specific Antibodies That Effectively Neutralize HIV-1

1 October 2017

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Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1

1 October 2017

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In planta protein sialylation through overexpression of the respective mammalian pathway

1 October 2017

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Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target

1 October 2017

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Protein tyrosine sulfation: a critical posttranslation modification in plants and animals

1 October 2017

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Identification of tyrosylprotein sulfotransferase in Arabidopsis.

1 October 2017

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Tyrosine sulfation: an increasingly recognised post-translational modification of secreted proteins

1 October 2017

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Identification of a receptor required for the anti-inflammatory activity of IVIG.

1 October 2017

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Analysis of immunoglobulin glycosylation by LC-ESI-MS of glycopeptides and oligosaccharides

1 October 2017

1 reference

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Recapitulation of IVIG anti-inflammatory activity with a recombinant IgG Fc.

1 October 2017

1 reference

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A unique beta1,3-galactosyltransferase is indispensable for the biosynthesis of N-glycans containing Lewis a structures in Arabidopsis thaliana

1 October 2017

1 reference

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Production of glucocerebrosidase with terminal mannose glycans for enzyme replacement therapy of Gaucher's disease using a plant cell system

1 October 2017

1 reference

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Molecular basis of N-acetylglucosaminyltransferase I deficiency in Arabidopsis thaliana plants lacking complex N-glycans

1 October 2017

1 reference

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Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120

1 October 2017

1 reference

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Lack of fucose on human IgG1 N-linked oligosaccharide improves binding to human Fcgamma RIII and antibody-dependent cellular toxicity

1 October 2017

1 reference

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Tyrosylprotein sulfotransferase: Purification and molecular cloning of an enzyme that catalyzes tyrosine O -sulfation, a common posttranslational modification of eukaryotic proteins

1 October 2017

1 reference

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Sulfation of Tyr1680 of human blood coagulation factor VIII is essential for the interaction of factor VIII with von Willebrand factor

1 October 2017

1 reference

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Safety and efficacy of two dose levels of taliglucerase alfa in pediatric patients with Gaucher disease

1 October 2017

1 reference

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Fc receptor but not complement binding is important in antibody protection against HIV.

2 July 2018

1 reference

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The human anti-HIV antibodies 2F5, 2G12, and PG9 differ in their susceptibility to proteolytic degradation: down-regulation of endogenous serine and cysteine proteinase activities could improve antibody production in plant-based expression platforms

2 July 2018

1 reference

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Targeted mutagenesis in the model plant Nicotiana benthamiana using Cas9 RNA-guided endonuclease

23 September 2018

1 reference

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Glycan profiles of the 27 N-glycosylation sites of the HIV envelope protein CN54gp140.

23 September 2018

1 reference

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Cellular repressor of E1A-stimulated genes is a bona fide lysosomal protein which undergoes proteolytic maturation during its biosynthesis.

23 September 2018

1 reference

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Generation of glyco-engineered Nicotiana benthamiana for the production of monoclonal antibodies with a homogeneous human-like N-glycan structure

23 September 2018

1 reference

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Conversion of recombinant hirudin to the natural form by in vitro tyrosine sulfation. Differential substrate specificities of leech and bovine tyrosylprotein sulfotransferases.

23 September 2018

1 reference

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Anti-Inflammatory Activity of Immunoglobulin G Resulting from Fc Sialylation

23 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073/PNAS.1509090112

HIV-1 gp120-specific antibody-dependent cell-mediated cytotoxicity correlates with rate of disease progression

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26417081

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1509090112

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26417081 AND SRC:MED&resulttype=core&format=json

25 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26417081 AND SRC:MED&resulttype=core&format=json

25 February 2020

PubMed publication ID

26417081

1 reference