Protein Tyrosine Phosphatase SHP-1 Modulates T Cell Responses by Controlling Cbl-b Degradation (Q36177042)

12 August 2017

Protein Tyrosine Phosphatase SHP-1 Modulates T Cell Responses by Controlling Cbl-b Degradation (English)

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12 August 2017

Yun Xiao

1

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12 August 2017

Guilin Qiao

2

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12 August 2017

Juan Tang

3

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12 August 2017

Rong Tang

4

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12 August 2017

Hui Guo

5

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12 August 2017

Samantha Warwar

6

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12 August 2017

Wallace Y Langdon

7

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12 August 2017

Lijian Tao

8

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12 August 2017

Jian Zhang

9

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12 August 2017

language of work or name

English

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publication date

28 September 2015

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12 August 2017

Journal of Immunology

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12 August 2017

195

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12 August 2017

9

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12 August 2017

4218-4227

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describes a project that uses

12 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4610872/fullTextXML

inferred from PubMed Central ID database lookup

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SHP-1 phosphatase activity counteracts increased T cell receptor affinity

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Nedd4 augments the adaptive immune response by promoting ubiquitin-mediated degradation of Cbl-b in activated T cells

1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins

1 October 2017

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1 October 2017

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WW domain HECT E3s target Cbl RING finger E3s for proteasomal degradation

1 October 2017

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Molecular modifiers of T cell antigen receptor triggering threshold: the mechanism of CD28 costimulatory receptor.

1 October 2017

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1 October 2017

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T cell response in experimental autoimmune encephalomyelitis (EAE): role of self and cross-reactive antigens in shaping, tuning, and regulating the autopathogenic T cell repertoire

1 October 2017

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Cbl-b-dependent coordinated degradation of the epidermal growth factor receptor signaling complex

1 October 2017

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Cbl-b regulates the CD28 dependence of T-cell activation.

1 October 2017

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The tyrosine phosphatase SHP-1 influences thymocyte selection by setting TCR signaling thresholds.

1 October 2017

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Tyrosine phosphorylation and complex formation of Cbl-b upon T cell receptor stimulation

1 October 2017

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Impaired Plasma Membrane Targeting of Grb2–Murine Son of Sevenless (mSOS) Complex and Differential Activation of the Fyn–T Cell Receptor (TCR)-ζ–Cbl Pathway Mediate T Cell Hyporesponsiveness in Autoimmune Nonobese Diabetic Mice

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4610872

Direct regulation of ZAP-70 by SHP-1 in T cell antigen receptor signaling

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4610872

PKC-theta modulates the strength of T cell responses by targeting Cbl-b for ubiquitination and degradation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4610872

B cell-specific deletion of protein-tyrosine phosphatase Shp1 promotes B-1a cell development and causes systemic autoimmunity.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4610872

Conditional deletion of Shp2 tyrosine phosphatase in thymocytes suppresses both pre-TCR and TCR signals

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4610872

Essential role of the E3 ubiquitin ligase Cbl-b in T cell anergy induction.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4610872

TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4610872

Cutting edge: Cbl-b: one of the key molecules tuning CD28- and CTLA-4-mediated T cell costimulation

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4610872

Involvement of the SHP-1 tyrosine phosphatase in regulation of T cell selection

21 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4610872

TCR affinity and negative regulation limit autoimmunity

21 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4610872

Cutting Edge: Regulation of T Cell Activation Threshold by CD28 Costimulation Through Targeting Cbl-b for Ubiquitination

5 December 2018

1 reference

12 December 2020

p38 mitogen-activated protein kinase mediates signal integration of TCR/CD28 costimulation in primary murine T cells

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12 December 2020

Cutting edge: the tyrosine phosphatase SHP-1 regulates thymocyte positive selection

1 reference

12 December 2020

Neutrophils Require SHP1 To Regulate IL-1 Production and Prevent Inflammatory Skin Disease

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12 December 2020

Dendritic Cell-Specific Ablation of the Protein Tyrosine Phosphatase Shp1 Promotes Th1 Cell Differentiation and Induces Autoimmunity

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12 December 2020

Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b

1 reference

12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.1501200

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12 August 2017

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12 August 2017

PubMed publication ID

26416283

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