Identification and functional characterization of novel transcriptional enhancers involved in regulating human GLI3 expression during early development. (Q36173741)

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English	Identification and functional characterization of novel transcriptional enhancers involved in regulating human GLI3 expression during early development.	scientific article

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27 February 2020

Identification and functional characterization of novel transcriptional enhancers involved in regulating human GLI3 expression during early development (English)

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27 February 2020

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27 February 2020

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27 February 2020

Yasuhiko Kawakami

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27 February 2020

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Saneela Anwar

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27 February 2020

Shahid Ali

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27 February 2020

Nicholas Lambert

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27 February 2020

Syed Sikandar Azam

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27 February 2020

Amir Ali Abbasi

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27 February 2020

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14 October 2015

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27 February 2020

Development, Growth and Differentiation

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27 February 2020

57

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27 February 2020

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27 February 2020

570-580

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27 February 2020

Cis-regulatory control of human GLI2 expression in the developing neural tube and limb bud.

1 reference

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1 October 2017

HAND2 targets define a network of transcriptional regulators that compartmentalize the early limb bud mesenchyme

1 reference

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1 October 2017

Nipbl and mediator cooperatively regulate gene expression to control limb development

1 reference

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1 October 2017

Dissection of a Ciona regulatory element reveals complexity of cross-species enhancer activity

1 reference

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The making of differences between fins and limbs

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1 October 2017

Differences in enhancer activity in mouse and zebrafish reporter assays are often associated with changes in gene expression

1 reference

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Lens development depends on a pair of highly conserved Sox21 regulatory elements

1 reference

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1 October 2017

Gli proteins in development and disease

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1 October 2017

Evolution of vertebrate appendicular structures: Insight from genetic and palaeontological data

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1 October 2017

Molecular analysis expands the spectrum of phenotypes associated with GLI3 mutations

1 reference

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1 October 2017

Arsenic antagonizes the Hedgehog pathway by preventing ciliary accumulation and reducing stability of the Gli2 transcriptional effector

1 reference

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1 October 2017

Human intronic enhancers control distinct sub-domains of Gli3 expression during mouse CNS and limb development

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MEME SUITE: tools for motif discovery and searching

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Heterochronic shift in Hox-mediated activation of sonic hedgehog leads to morphological changes during fin development

1 reference

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1 October 2017

Gli3-deficient mice exhibit cleft palate associated with abnormal tongue development

1 reference

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1 October 2017

Tol2: a versatile gene transfer vector in vertebrates

1 reference

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1 October 2017

The Gli code: an information nexus regulating cell fate, stemness and cancer.

1 reference

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1 October 2017

Ultraconserved non-coding sequence element controls a subset of spatiotemporal GLI3 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4609622

1 October 2017

Human GLI3 intragenic conserved non-coding sequences are tissue-specific enhancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4609622

1 October 2017

In vivo enhancer analysis of human conserved non-coding sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4609622

1 October 2017

Gli2 and Gli3 play distinct roles in the dorsoventral patterning of the mouse hindbrain

1 reference

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1 October 2017

Anteroposterior patterning in the limb and digit specification: contribution of mouse genetics

1 reference

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1 October 2017

The pectoral fin of Tiktaalik roseae and the origin of the tetrapod limb

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4609622

1 October 2017

Highly conserved non-coding sequences are associated with vertebrate development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4609622

1 October 2017

Zebrafish Gli3 functions as both an activator and a repressor in Hedgehog signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4609622

1 October 2017

Scanning Human Gene Deserts for Long-Range Enhancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4609622

1 October 2017

LAGAN and Multi-LAGAN: efficient tools for large-scale multiple alignment of genomic DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4609622

1 October 2017

TRANSFAC: transcriptional regulation, from patterns to profiles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4609622

1 October 2017

Mouse GLI3 regulates Fgf8 expression and apoptosis in the developing neural tube, face, and limb bud

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4609622

1 October 2017

De novo GLI3 mutation in acrocallosal syndrome: broadening the phenotypic spectrum of GLI3 defects and overlap with murine models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4609622

1 October 2017

A novel gene, GliH1, with homology to the Gli zinc finger domain not required for mouse development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4609622

1 October 2017

Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4609622

1 October 2017

Mutual genetic antagonism involving GLI3 and dHAND prepatterns the vertebrate limb bud mesenchyme prior to SHH signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4609622

1 October 2017

Phosphorylation and microtubule association of the Opitz syndrome protein mid-1 is regulated by protein phosphatase 2A via binding to the regulatory subunit alpha 4.

1 reference

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1 October 2017

VISTA : visualizing global DNA sequence alignments of arbitrary length

1 reference

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Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4609622

1 October 2017

The phenotypic spectrum of GLI3 morphopathies includes autosomal dominant preaxial polydactyly type-IV and postaxial polydactyly type-A/B; No phenotype prediction from the position of GLI3 mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4609622

1 October 2017

GLI3 mutations in human disorders mimic Drosophila cubitus interruptus protein functions and localization

1 reference

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1 October 2017

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1 reference

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Mutation in GLI3 in postaxial polydactyly type A

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1 October 2017

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1 October 2017

Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4609622

1 October 2017

Stages of embryonic development of the zebrafish

1 reference

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1 October 2017

A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4609622

1 October 2017

Expression of the zinc finger gene Gli3 is affected in the morphogenetic mouse mutant extra-toes (Xt)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4609622

1 October 2017

A novel Gli3 enhancer controls the Gli3 spatiotemporal expression pattern through a TALE homeodomain protein binding site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4609622

2 July 2018

STAMP: a web tool for exploring DNA-binding motif similarities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4609622

2 July 2018

Gli2 and Gli3 have redundant and context-dependent function in skeletal muscle formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4609622

2 July 2018

GLI3 zinc-finger gene interrupted by translocations in Greig syndrome families

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4609622

27 July 2018

Cis-regulatory underpinnings of human GLI3 expression in embryonic craniofacial structures and internal organs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4609622

23 September 2018

Gli3 and Plzf cooperate in proximal limb patterning at early stages of limb development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4609622

23 September 2018

Characterization of the pufferfish Otx2 cis-regulators reveals evolutionarily conserved genetic mechanisms for vertebrate head specification.

1 reference

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23 September 2018

Progression of vertebrate limb development through SHH-mediated counteraction of GLI3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4609622

23 September 2018

GLI3 frameshift mutations cause autosomal dominant Pallister-Hall syndrome

1 reference

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23 September 2018

Evidence for allelism of the recessive insertional mutation add and the dominant mouse mutation extra-toes (Xt)

1 reference

https://pubmed.ncbi.nlm.nih.gov/26464005

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mouse mutant Polydactyly Nagoya (Pdn) defines a novel allele of the zinc finger gene Gli3

1 reference

https://pubmed.ncbi.nlm.nih.gov/26464005

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluating the biological relevance of putative enhancers using Tol2 transposon-mediated transgenesis in zebrafish

1 reference

https://pubmed.ncbi.nlm.nih.gov/26464005

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1111/DGD.12239

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26464005 AND SRC:MED&resulttype=core&format=json

27 February 2020

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27 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

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27 February 2020

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