Rho-GTPase and Atherosclerosis: Pleiotropic Effects of Statins (Q36168823)

12 August 2017

10 references

22 March 2019

17 June 2019

28 September 2019

2 October 2019

10 October 2019

20 November 2019

28 November 2019

21 July 2020

30 January 2021

26 October 2022

Rho-GTPase and Atherosclerosis: Pleiotropic Effects of Statins (English)

1 reference

12 August 2017

8 references

22 March 2019

17 June 2019

28 September 2019

2 October 2019

10 October 2019

20 November 2019

28 November 2019

21 July 2020

1 reference

28 September 2019

1 reference

2 October 2019

1 reference

10 October 2019

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20 November 2019

1 reference

28 November 2019

2 references

21 July 2020

30 January 2021

1 reference

Anping Cai

1

1 reference

12 August 2017

Yingling Zhou

series ordinal

2

1 reference

12 August 2017

Liwen Li

series ordinal

3

1 reference

12 August 2017

language of work or name

1 reference

29 June 2015

11 references

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

12 August 2017

22 March 2019

17 June 2019

28 September 2019

2 October 2019

10 October 2019

20 November 2019

28 November 2019

21 July 2020

30 January 2021

26 October 2022

11 references

12 August 2017

22 March 2019

17 June 2019

28 September 2019

2 October 2019

10 October 2019

20 November 2019

28 November 2019

21 July 2020

30 January 2021

26 October 2022

4

1 reference

12 August 2017

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Creative Commons Attribution-NonCommercial 4.0 International

12 August 2017

10 references

22 March 2019

17 June 2019

28 September 2019

2 October 2019

10 October 2019

20 November 2019

28 November 2019

21 July 2020

30 January 2021

on focus list of Wikimedia project

26 October 2022

ScienceSource

0 references

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Evidence for statin pleiotropy in humans: differential effects of statins and ezetimibe on rho-associated coiled-coil containing protein kinase activity, endothelial function, and inflammation

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1 October 2017

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ROCK1 mediates leukocyte recruitment and neointima formation following vascular injury

1 October 2017

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Rho kinase inhibition improves endothelial function in human subjects with coronary artery disease

1 October 2017

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RhoA is highly up‐regulated in the process of early heart development of the chick and important for normal embryogenesis

1 October 2017

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1 October 2017

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Effects of atorvastatin on stroke in patients with unstable angina or non-Q-wave myocardial infarction: a Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) substudy

1 October 2017

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1 October 2017

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Rho-kinase mediates hypoxia-induced downregulation of endothelial nitric oxide synthase

1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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Smooth muscle differentiation marker gene expression is regulated by RhoA-mediated actin polymerization

1 October 2017

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The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals

1 October 2017

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New insights into the pharmacodynamic and pharmacokinetic properties of statins.

1 October 2017

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Distinct roles for the small GTPases Cdc42 and Rho in endothelial responses to shear stress

1 October 2017

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Prevention of Cardiovascular Events and Death with Pravastatin in Patients with Coronary Heart Disease and a Broad Range of Initial Cholesterol Levels

1 October 2017

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A role for Cdc42 in macrophage chemotaxis

1 October 2017

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Upregulation of Endothelial Nitric Oxide Synthase by HMG CoA Reductase Inhibitors

1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)

1 October 2017

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1 October 2017

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1 October 2017

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Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines

1 October 2017

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Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent

1 October 2017

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Involvement of geranylgeranylation of Rho and Rac GTPases in adipogenic and RANKL expression, which was inhibited by simvastatin

2 July 2018

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The Rho exchange factor Arhgef1 mediates the effects of angiotensin II on vascular tone and blood pressure.

23 September 2018

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Fasudil attenuates sympathetic nervous activity in the adrenal medulla of spontaneously hypertensive rats

23 September 2018

1 reference

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Rho-kinase phosphorylates eNOS at threonine 495 in endothelial cells.

23 September 2018

1 reference

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Simvastatin modulates chemokine and chemokine receptor expression by geranylgeranyl isoprenoid pathway in human endothelial cells and macrophages

23 September 2018

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Cardioprotective mechanisms of Rho-kinase inhibition associated with eNOS and oxidative stress-LOX-1 pathway in Dahl salt-sensitive hypertensive rats

23 September 2018

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Statins suppress oxidized low density lipoprotein-induced macrophage proliferation by inactivation of the small G protein-p38 MAPK pathway

23 September 2018

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Rho-associated protein kinase contributes to early atherosclerotic lesion formation in mice

23 September 2018

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Direct Anti-Inflammatory Mechanisms Contribute to Attenuation of Experimental Allograft Arteriosclerosis by Statins

23 September 2018

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Inhibition of Contraction and Myosin Light Chain Phosphorylation in Guinea‐Pig Smooth Muscle by p21‐Activated Kinase 1

23 September 2018

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Simvastatin reduces neointimal thickening in low-density lipoprotein receptor-deficient mice after experimental angioplasty without changing plasma lipids

23 September 2018

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Rho-GTPase-dependent platelet-neutrophil interaction affected by HMG-CoA reductase inhibition with altered adenosine nucleotide release and function

23 September 2018

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Statins have biphasic effects on angiogenesis

23 September 2018

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Monocyte adhesion and spreading on human endothelial cells is dependent on Rho-regulated receptor clustering

23 September 2018

1 reference

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Regulation of TNF-alpha-induced reorganization of the actin cytoskeleton and cell-cell junctions by Rho, Rac, and Cdc42 in human endothelial cells

23 September 2018

1 reference

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Long-term atorvastatin improves age-related endothelial dysfunction by ameliorating oxidative stress and normalizing eNOS/iNOS imbalance in rat aorta

23 September 2018

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12 December 2020

Phosphorylation of caldesmon by p21-activated kinase. Implications for the Ca(2 ) sensitivity of smooth muscle contraction

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12 December 2020

Inhibition of rho-associated kinase results in suppression of neointimal formation of balloon-injured arteries

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12 December 2020

Gene transfer of dominant negative Rho kinase suppresses neointimal formation after balloon injury in pigs

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12 December 2020

The small G-protein Rac mediates depolarization-induced superoxide formation in human endothelial cells

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12 December 2020

Statins as a newly recognized type of immunomodulator

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12 December 2020

Increased number of high sensitive platelets in hypercholesterolemia, cardiovascular diseases, and after incubation with cholesterol

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12 December 2020

Cell cycle progression: new therapeutic target for vascular proliferative disease

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12 December 2020

Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase

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12 December 2020

Shear-induced tyrosine phosphorylation in endothelial cells requires Rac1-dependent production of ROS

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12 December 2020

Atherosclerosis--an inflammatory disease

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12 December 2020

3-Hydroxy-3-methylglutaryl-CoA reductase inhibitors attenuate vascular smooth muscle proliferation by preventing rho GTPase-induced down-regulation of p27(Kip1)

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12 December 2020

Rac1 and superoxide are required for the expression of cell adhesion molecules induced by tumor necrosis factor-alpha in endothelial cells

1 reference

12 December 2020

The RhoA/Rho kinase pathway regulates nuclear localization of serum response factor

1 reference

12 December 2020

Biosynthesis and characterization of (S)-and (R)-3-hydroxy-3-methylglutaryl coenzyme A

1 reference

12 December 2020

Inhibition of endothelial-derived nitric oxide promotes P-selectin expression and actions in the rat microcirculation

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12 December 2020

Interleukin-18-induced human coronary artery smooth muscle cell migration is dependent on NF-kappaB- and AP-1-mediated matrix metalloproteinase-9 expression and is inhibited by atorvastatin

1 reference

12 December 2020

Meta-analysis of cardiovascular outcomes trials comparing intensive versus moderate statin therapy

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12 December 2020

Efficacy of Atorvastatin combined with adipose-derived mesenchymal stem cell transplantation on cardiac function in rats with acute myocardial infarction

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12 December 2020

Identifiers

DOI

10.1161/JAHA.115.002113

1 reference

release_lmrnsy4hiff43bdrmlqsaij7aq

12 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/lmrnsy4hiff43bdrmlqsaij7aq

24 November 2022

mapped directly with Wikidata item

1 reference

12 August 2017

PubMed publication ID

26124206

1 reference