Comparative genomic analysis of primary versus metastatic colorectal carcinomas. (Q36157662)

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3 February 2020

title

Comparative genomic analysis of primary versus metastatic colorectal carcinomas (English)

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4

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Jinru Shia

6

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Leonard B. Saltz

14

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9

Michael D'Angelica

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3 February 2020

author name string

Efsevia Vakiani

1

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3 February 2020

Manickam Janakiraman

2

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3 February 2020

Ronglai Shen

3

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Zhaoshi Zeng

5

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Andrea Cercek

7

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3 February 2020

Nancy Kemeny

8

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3 February 2020

Agnes Viale

10

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Adriana Heguy

11

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Philip Paty

12

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Timothy A Chan

13

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Martin Weiser

15

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David B Solit

16

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language of work or name

English

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publication date

4 June 2012

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Journal of Clinical Oncology

3 February 2020

published in

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volume

30

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issue

24

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3 February 2020

page(s)

2956-2962

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KRAS mutation detection in paired frozen and Formalin-Fixed Paraffin-Embedded (FFPE) colorectal cancer tissues

3 February 2020

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1 reference

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2 October 2017

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KRAS mutation analysis: a comparison between primary tumours and matched liver metastases in 305 colorectal cancer patients.

2 October 2017

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Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis

2 October 2017

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Genomic and biological characterization of exon 4 KRAS mutations in human cancer

2 October 2017

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A metastasis or a second independent cancer? Evaluating the clonal origin of tumors using array copy number data

2 October 2017

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KRAS and BRAF mutational status in primary colorectal tumors and related metastatic sites: biological and clinical implications

2 October 2017

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Genomic and mutational profiling to assess clonal relationships between multiple non-small cell lung cancers

2 October 2017

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KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer.

2 October 2017

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High sensitivity of both sequencing and real-time PCR analysis of KRAS mutations in colorectal cancer tissue

2 October 2017

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TP53 mutations predict disease control in metastatic colorectal cancer treated with cetuximab-based chemotherapy

2 October 2017

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PIK3CA mutations in colorectal cancer are associated with clinical resistance to EGFR-targeted monoclonal antibodies

2 October 2017

1 reference

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American Society of Clinical Oncology provisional clinical opinion: testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapy

2 October 2017

1 reference

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Genetic predictors of MEK dependence in non-small cell lung cancer

2 October 2017

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Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer

2 October 2017

1 reference

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K-ras mutations and benefit from cetuximab in advanced colorectal cancer.

2 October 2017

1 reference

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Integrated detection and population-genetic analysis of SNPs and copy number variation

2 October 2017

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Comprehensive genomic characterization defines human glioblastoma genes and core pathways

2 October 2017

1 reference

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Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer

2 October 2017

1 reference

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KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab.

2 October 2017

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A faster circular binary segmentation algorithm for the analysis of array CGH data

2 October 2017

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2 October 2017

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Synchronous and 'early' metachronous carcinomas of the colon and rectum

2 October 2017

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A genetic model for colorectal tumorigenesis

2 October 2017

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2 October 2017

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PIK3CA mutations are not a major determinant of resistance to the epidermal growth factor receptor inhibitor cetuximab in metastatic colorectal cancer

2 July 2018

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23 September 2018

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Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies.

23 September 2018

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23 September 2018

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12 December 2020

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12 December 2020

KRAS and BRAF oncogenic mutations in MSS colorectal carcinoma progression

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12 December 2020

High-Resolution Mapping of DNA Breakpoints to Define True Recurrences Among Ipsilateral Breast Cancers

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12 December 2020

Association of K-ras mutational status and clinical outcomes in patients with metastatic colorectal cancer receiving panitumumab alone

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12 December 2020

High concordance of KRAS status between primary colorectal tumors and related metastatic sites: implications for clinical practice

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12 December 2020

PI3KCA/PTEN deregulation contributes to impaired responses to cetuximab in metastatic colorectal cancer patients

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12 December 2020

Identifiers

DOI

10.1200/JCO.2011.38.2994

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22665543 AND SRC:MED&resulttype=core&format=json

3 February 2020

1 reference

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3 February 2020

PubMed publication ID

22665543

1 reference