Stress hematopoiesis reveals abnormal control of self-renewal, lineage bias, and myeloid differentiation in Mll partial tandem duplication (Mll-PTD) hematopoietic stem/progenitor cells (Q36141856)

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English	Stress hematopoiesis reveals abnormal control of self-renewal, lineage bias, and myeloid differentiation in Mll partial tandem duplication (Mll-PTD) hematopoietic stem/progenitor cells	scientific article

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12 August 2017

Stress hematopoiesis reveals abnormal control of self-renewal, lineage bias, and myeloid differentiation in Mll partial tandem duplication (Mll-PTD) hematopoietic stem/progenitor cells (English)

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12 August 2017

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H. Leighton Grimes

17

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H Leighton Grimes

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12 August 2017

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Guido Marcucci

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Michael A Caligiuri

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Michael A Caligiuri

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12 August 2017

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Yue Zhang

1

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12 August 2017

Xiaomei Yan

2

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12 August 2017

Goro Sashida

3

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12 August 2017

Xinghui Zhao

4

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12 August 2017

Yalan Rao

5

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12 August 2017

Susumu Goyama

6

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12 August 2017

Susan P Whitman

7

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12 August 2017

Nicholas Zorko

8

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12 August 2017

Kelsie Bernot

9

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12 August 2017

Rajeana M Conway

10

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12 August 2017

David Witte

11

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12 August 2017

Qian-Fei Wang

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12 August 2017

Daniel G Tenen

13

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Zhijian Xiao

14

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12 August 2017

James C Mulloy

16

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Gang Huang

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publication date

26 June 2012

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12 August 2017

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12 August 2017

120

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12 August 2017

5

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12 August 2017

1118-1129

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12 August 2017

The MLL partial tandem duplication in adults aged 60 years and older with de novo cytogenetically normal acute myeloid leukemia

1 reference

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2 October 2017

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

1 reference

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2 October 2017

Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing

1 reference

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2 October 2017

Mutations in epigenetic regulators in myelodysplastic syndromes

1 reference

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2 October 2017

Genetics of myelodysplastic syndromes: new insights

1 reference

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2 October 2017

RUNX1 mutations in clonal myeloid disorders: from conventional cytogenetics to next generation sequencing, a story 40 years in the making

1 reference

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2 October 2017

The ability of MLL to bind RUNX1 and methylate H3K4 at PU.1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations.

1 reference

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2 October 2017

PAFc, a key player in MLL-rearranged leukemogenesis

1 reference

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2 October 2017

Phase 2 study of romiplostim in patients with low- or intermediate-risk myelodysplastic syndrome receiving azacitidine therapy

1 reference

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2 October 2017

Gene expression patterns in myelodyplasia underline the role of apoptosis and differentiation in disease initiation and progression.

1 reference

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2 October 2017

Recurring mutations found by sequencing an acute myeloid leukemia genome

1 reference

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2 October 2017

The Mll partial tandem duplication: differential, tissue-specific activity in the presence or absence of the wild-type allele

1 reference

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2 October 2017

Malignant transformation initiated by Mll-AF9: gene dosage and critical target cells

1 reference

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2 October 2017

Unique and independent roles for MLL in adult hematopoietic stem cells and progenitors

1 reference

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2 October 2017

Supportive care and use of hematopoietic growth factors in myelodysplastic syndromes

1 reference

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2 October 2017

Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia

1 reference

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2 October 2017

Retroviral vector insertion sites associated with dominant hematopoietic clones mark "stemness" pathways

1 reference

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2 October 2017

Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations

1 reference

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2 October 2017

The MLL partial tandem duplication in acute myeloid leukaemia

1 reference

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2 October 2017

Chromatin structural elements and chromosomal translocations in leukemia

1 reference

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2 October 2017

Chromosomal translocations involving the MLL gene: molecular mechanisms

1 reference

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2 October 2017

The role of rHuEpo in low-risk myelodysplastic syndrome patients.

1 reference

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2 October 2017

A COMPASS in the voyage of defining the role of trithorax/MLL-containing complexes: linking leukemogensis to covalent modifications of chromatin

1 reference

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2 October 2017

The MLL partial tandem duplication: evidence for recessive gain-of-function in acute myeloid leukemia identifies a novel patient subgroup for molecular-targeted therapy

1 reference

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2 October 2017

Differential STAT5 signaling by ligand-dependent and constitutively active cytokine receptors.

1 reference

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2 October 2017

MLL targets SET domain methyltransferase activity to Hox gene promoters

1 reference

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2 October 2017

Thrombopoietin regulates Bcl-xL gene expression through Stat5 and phosphatidylinositol 3-kinase activation pathways

1 reference

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2 October 2017

The mll-AF9 gene fusion in mice controls myeloproliferation and specifies acute myeloid leukaemogenesis

1 reference

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2 October 2017

In vitro self-renewal division of hematopoietic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412332

2 July 2018

Oncogenic Transcription Factors in the Human Acute Leukemias

1 reference

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2 July 2018

An accumulation of cytogenetic and molecular genetic events characterizes the progression from MDS to secondary AML: an analysis of 38 paired samples analyzed by cytogenetics, molecular mutation analysis and SNP microarray profiling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412332

23 September 2018

Gene expression profiling of pediatric acute myelogenous leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412332

23 September 2018

Expression of APO2.7, bcl-2 and bax apoptosis-associated proteins in CD34- bone marrow cell compartments from patients with myelodysplastic syndromes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412332

23 September 2018

Bcl-XL expression in stem cells facilitates engraftment and reduces the need for host conditioning during bone marrow transplantation

1 reference

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23 September 2018

Dimerization of MLL fusion proteins immortalizes hematopoietic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412332

23 September 2018

Comparative analysis of MLL partial tandem duplication and FLT3 internal tandem duplication mutations in 956 adult patients with acute myeloid leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412332

23 September 2018

The role of apoptosis, proliferation, and the Bcl-2-related proteins in the myelodysplastic syndromes and acute myeloid leukemia secondary to MDS.

1 reference

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23 September 2018

ALL-1 tandem duplication in acute myeloid leukemia with a normal karyotype involves homologous recombination between Alu elements.

1 reference

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23 September 2018

Myelodysplastic Syndromes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412332

5 December 2018

Apoptosis in patients with myelodysplastic syndromes: differential involvement of marrow cells in 'good' versus 'poor' prognosis patients and correlation with apoptosis-related genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22740449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and prognostic significance of Bcl-2 family proteins in myelodysplastic syndromes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22740449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The in vivo effect of recombinant human interleukin-1 receptor antagonist on spleen colony forming cells after radiation induced myelosuppression

1 reference

https://pubmed.ncbi.nlm.nih.gov/22740449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RUNX1 mutations are frequent in de novo AML with noncomplex karyotype and confer an unfavorable prognosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22740449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation analysis for RUNX1, MLL-PTD, FLT3-ITD, NPM1 and NRAS in 269 patients with MDS or secondary AML

1 reference

https://pubmed.ncbi.nlm.nih.gov/22740449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

'Low-risk' myelodysplastic syndrome is associated with excessive apoptosis and an increased ratio of pro- versus anti-apoptotic bcl-2-related proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/22740449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis, bcl-2 expression and p53 accumulation in myelodysplastic syndrome, myelodysplastic-syndrome-derived acute myelogenous leukemia and de novo acute myelogenous leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22740449

12 December 2020

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inferred from PubMed ID database lookup

Molecular rearrangement of the ALL-1 gene in acute myeloid leukemia without cytogenetic evidence of 11q23 chromosomal translocations

1 reference

https://pubmed.ncbi.nlm.nih.gov/22740449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of fusion partner genes in 114 patients with de novo acute myeloid leukemia and MLL rearrangement

1 reference

https://pubmed.ncbi.nlm.nih.gov/22740449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Partial tandem duplication of ALL1 as a recurrent molecular defect in acute myeloid leukemia with trisomy 11

1 reference

https://pubmed.ncbi.nlm.nih.gov/22740449

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myelodysplasia and leukemia of Fanconi anemia are associated with a specific pattern of genomic abnormalities that includes cryptic RUNX1/AML1 lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/22740449

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based on heuristic

inferred from PubMed ID database lookup

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10.1182/BLOOD-2012-02-412379

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Europe PubMed Central

PMC publication ID

12 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PubMed publication ID

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Europe PubMed Central

PMC publication ID

12 August 2017

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