Sinomenine, a natural dextrorotatory morphinan analog, is anti-inflammatory and neuroprotective through inhibition of microglial NADPH oxidase. (Q36119968)

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English	Sinomenine, a natural dextrorotatory morphinan analog, is anti-inflammatory and neuroprotective through inhibition of microglial NADPH oxidase.	scientific article

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7 January 2020

Sinomenine, a natural dextrorotatory morphinan analog, is anti-inflammatory and neuroprotective through inhibition of microglial NADPH oxidase (English)

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7 January 2020

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7 January 2020

Jau-Shyong Hong

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7 January 2020

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Li Qian

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7 January 2020

Wei Zhang

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7 January 2020

Belinda Wilson

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7 January 2020

Patrick M Flood

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19 September 2007

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7 January 2020

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https://jneuroinflammation.biomedcentral.com/counter/pdf/10.1186/1742-2094-4-23

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19 March 2024

https://api.unpaywall.org/v2/10.1186/[email protected]

Journal of Neuroinflammation

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7 January 2020

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7 January 2020

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19 March 2024

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Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism

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MPTP and SNpc DA neuronal vulnerability: role of dopamine, superoxide and nitric oxide in neurotoxicity. Minireview

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2 October 2017

Activation and assembly of the NADPH oxidase: a structural perspective

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2 October 2017

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2 October 2017

Microglia: a sensor for pathological events in the CNS

1 reference

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Impairment of macrophage eicosanoid and nitric oxide production by an alkaloid from Sinomenium acutum.

1 reference

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2 October 2017

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2 October 2017

Pharmacology of sinomenine, an anti-rheumatic alkaloid from Sinomenium acutum

1 reference

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2 October 2017

Neuroinflammation alters the hippocampal pattern of behaviorally induced Arc expression.

1 reference

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2 July 2018

Immunomodulatory effects of the alkaloid sinomenine in the high responder ACI-to-Lewis cardiac allograft model.

1 reference

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Pituitary adenylate cyclase-activating polypeptide (PACAP) 38 and PACAP4-6 are neuroprotective through inhibition of NADPH oxidase: potent regulators of microglia-mediated oxidative stress.

1 reference

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23 September 2018

Interleukin-10 protects lipopolysaccharide-induced neurotoxicity in primary midbrain cultures by inhibiting the function of NADPH oxidase

1 reference

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23 September 2018

Microglial NADPH oxidase is a novel target for femtomolar neuroprotection against oxidative stress.

1 reference

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23 September 2018

Effect of sinomenine on cytokine expression of macrophages and synoviocytes in adjuvant arthritis rats

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23 September 2018

The effect of sinomenine on cyclooxygenase activity and the expression of COX-1 and COX-2 mRNA in human peripheral monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064906

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NADPH oxidase mediates lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia.

1 reference

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23 September 2018

Critical role of microglial NADPH oxidase-derived free radicals in the in vitro MPTP model of Parkinson's disease.

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23 September 2018

Study progress in Sinomenium acutum (Thunb.) Rehd. et Wils

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23 September 2018

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1 reference

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Superoxide produced by activated neutrophils efficiently reduces the tetrazolium salt, WST-1 to produce a soluble formazan: a simple colorimetric assay for measuring respiratory burst activation and for screening anti-inflammatory agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/17880684

12 December 2020

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Reduction by naloxone of lipopolysaccharide-induced neurotoxicity in mouse cortical neuron–glia co-cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/17880684

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Regional difference in susceptibility to lipopolysaccharide-induced neurotoxicity in the rat brain: role of microglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17880684

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The pharmacology of sinomenine. VII. Effect of sinomenine on the gastro-intestinal movement and its mechanism

1 reference

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Effects of beta endorphin on specific immune responses in man

1 reference

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Respiratory burst inhibition in human neutrophils by ultra-low doses of [D-Ala2 ]methionine enkephalinamide

1 reference

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Protection by sinomenine against endotoxin-induced fulminant hepatitis in galactosamine-sensitized mice

1 reference

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12 December 2020

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Amelioration of rat experimental arthritides by treatment with the alkaloid sinomenine

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Synergistic effects of the alkaloid sinomenine in combination with the immunosuppressive drugs tacrolimus and mycophenolic acid

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https://pubmed.ncbi.nlm.nih.gov/17880684

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10.1186/1742-2094-4-23

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7 January 2020

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