Thrombospondin-1 (TSP-1) analogs ABT-510 and ABT-898 inhibit prolactinoma growth and recover active pituitary transforming growth factor-β1 (TGF-β1). (Q36113958)

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English	Thrombospondin-1 (TSP-1) analogs ABT-510 and ABT-898 inhibit prolactinoma growth and recover active pituitary transforming growth factor-β1 (TGF-β1).	scientific article

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Thrombospondin-1 (TSP-1) analogs ABT-510 and ABT-898 inhibit prolactinoma growth and recover active pituitary transforming growth factor-β1 (TGF-β1). (English)

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

1 reference

based on heuristic

inferred from title

author name string

M Victoria Recouvreux

1

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

M Andrea Camilletti

2

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Europe PubMed Central

PMC publication ID

12 August 2017

Daniel B Rifkin

3

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Damasia Becu-Villalobos

4

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Graciela Díaz-Torga

5

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Europe PubMed Central

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12 August 2017

language of work or name

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publication date

14 June 2012

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Europe PubMed Central

PMC publication ID

12 August 2017

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Europe PubMed Central

PMC publication ID

12 August 2017

153

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Europe PubMed Central

PMC publication ID

12 August 2017

8

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

3861-3871

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Active and total transforming growth factor-β1 are differentially regulated by dopamine and estradiol in the pituitary

1 reference

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From antiangiogenesis to hypoxia: current research and future directions

1 reference

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2 October 2017

Resistant prolactinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404347

2 October 2017

Dopamine agonist–resistant prolactinomas

1 reference

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2 October 2017

The thrombospondin-1 mimetic ABT-510 increases the uptake and effectiveness of cisplatin and paclitaxel in a mouse model of epithelial ovarian cancer

1 reference

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CD36, a scavenger receptor involved in immunity, metabolism, angiogenesis, and behavior

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Perturbation of transforming growth factor (TGF)-beta1 association with latent TGF-beta binding protein yields inflammation and tumors

1 reference

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VEGF inhibition: insights from preclinical and clinical studies

1 reference

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2 October 2017

Tumor angiogenesis

1 reference

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New therapeutic directions for advanced pancreatic cancer: targeting the epidermal growth factor and vascular endothelial growth factor pathways

1 reference

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A phase II study of ABT-510 (thrombospondin-1 analog) for the treatment of metastatic melanoma

1 reference

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2 October 2017

Thrombospondin-1 peptide ABT-510 combined with valproic acid is an effective antiangiogenesis strategy in neuroblastoma

1 reference

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2 October 2017

Pathohistological classification of pituitary tumors: 10 years of experience with the German Pituitary Tumor Registry

1 reference

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2 October 2017

What are the markers of aggressiveness in prolactinomas? Changes in cell biology, extracellular matrix components, angiogenesis and genetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404347

2 October 2017

Changes in thrombospondin-1 levels in the endothelial cells of the anterior pituitary during estrogen-induced prolactin-secreting pituitary tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404347

2 October 2017

Genesis of prolactinomas: studies using estrogen-treated animals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404347

2 October 2017

Thrombospondin-1 mimetic peptide inhibitors of angiogenesis and tumor growth: design, synthesis, and optimization of pharmacokinetics and biological activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404347

2 October 2017

Increased pituitary vascular endothelial growth factor-a in dopaminergic D2 receptor knockout female mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404347

2 October 2017

Latent transforming growth factor-beta (TGF-beta) binding proteins: orchestrators of TGF-beta availability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404347

2 October 2017

The tryptophan-rich motifs of the thrombospondin type 1 repeats bind VLAL motifs in the latent transforming growth factor-beta complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404347

2 October 2017

Expression of latent TGF-beta binding protein LTBP-1 is hormonally regulated in normal and transformed human lung fibroblasts

1 reference

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2 October 2017

TGF-beta and the Smad signal transduction pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404347

2 October 2017

Vascular endothelial growth factor, its receptor KDR/Flk-1, and pituitary tumor transforming gene in pituitary tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404347

2 October 2017

Intra-tumoural microvessel density in human solid tumours.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404347

2 October 2017

Thrombospondin-1 as an endogenous inhibitor of angiogenesis and tumor growth.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404347

2 October 2017

Functional role of estrogen in pituitary tumor pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404347

2 October 2017

Pituitary tumors: pathophysiology, clinical manifestations and management

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404347

2 October 2017

CD36: a class B scavenger receptor involved in angiogenesis, atherosclerosis, inflammation, and lipid metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404347

2 October 2017

Early involvement of estrogen-induced pituitary tumor transforming gene and fibroblast growth factor expression in prolactinoma pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404347

2 October 2017

Pathogenesis of pituitary tumors

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404347

2 October 2017

Role of transforming growth factor (TGF)-beta Type I and TGF-beta type II receptors in the TGF-beta1-regulated gene expression in pituitary prolactin-secreting lactotropes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404347

2 October 2017

Antiproliferative and antitumor activities of D‐reverse peptides derived from the second type‐1 repeat of thrombospondin‐1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404347

2 October 2017

Latent transforming growth factor-beta 1 and its binding protein are components of extracellular matrix microfibrils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404347

2 October 2017

Latent transforming growth factor-beta 1 associates to fibroblast extracellular matrix via latent TGF-beta binding protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404347

2 October 2017

Reduction in the expression and action of transforming growth factor beta 1 on lactotropes during estrogen-induced tumorigenesis in the anterior pituitary

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404347

2 October 2017

Direct arterial vascularization of estrogen-induced prolactin-secreting anterior pituitary tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404347

2 October 2017

Ultrastructural changes in the capillary bed of human pituitary tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404347

2 October 2017

Latent forms of TGF-beta: molecular structure and mechanisms of activation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404347

2 October 2017

Independent promoters regulate the expression of two amino terminally distinct forms of latent transforming growth factor-beta binding protein-1 (LTBP-1) in a cell type-specific manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404347

2 July 2018

Transforming growth factor-beta 1 messenger RNA and protein expression in the pituitary gland: its action on prolactin secretion and lactotropic growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404347

2 July 2018

Inhibitory effects of antivascular endothelial growth factor strategies in experimental dopamine-resistant prolactinomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404347

23 September 2018

A Thrombospondin-Mimetic Peptide, ABT-898, Suppresses Angiogenesis and Promotes Follicular Atresia in Pre- and Early-Antral Follicles in Vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404347

23 September 2018

A phase 1 trial of ABT-510 concurrent with standard chemoradiation for patients with newly diagnosed glioblastoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404347

23 September 2018

Invasive giant prolactinoma with loss of therapeutic response to cabergoline: expression of angiogenic markers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404347

23 September 2018

ABT-510, a modified type 1 repeat peptide of thrombospondin, inhibits malignant glioma growth in vivo by inhibiting angiogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404347

23 September 2018

The epidemiology of prolactinomas.

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23 September 2018

Angiogenesis research: guidelines for translation to clinical application.

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23 September 2018

Pituitary lactotrope expresses transforming growth factor beta (TGF beta) type II receptor mRNA and protein and contains 125I-TGF beta 1 binding sites

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404347

23 September 2018

VEGF and CD31 association in pituitary adenomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/22700773

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factor beta 1-like immunoreactivity in the pituitary gland of the rat: effect of estrogen

1 reference

https://pubmed.ncbi.nlm.nih.gov/22700773

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiogenesis in Pituitary Adenomas and the Normal Pituitary Gland

1 reference

https://pubmed.ncbi.nlm.nih.gov/22700773

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based on heuristic

inferred from PubMed ID database lookup

Phase 2 study of ABT-510 in patients with previously untreated advanced renal cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22700773

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based on heuristic

inferred from PubMed ID database lookup

Effect of angiogenesis inhibitor TNP-470 on vascular formation in pituitary tumors induced by estrogen in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/22700773

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular Endothelial Growth Factor (VEGF) Expression in Human Pituitary Adenomas and Carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/22700773

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phase 1 trial of 2 dose schedules of ABT-510, an antiangiogenic, thrombospondin-1-mimetic peptide, in patients with advanced cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22700773

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of estrogen-induced anterior pituitary enlargement and arteriogenesis by bromocriptine in Fischer 344 rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/22700773

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/22700773

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombospondin binds and activates the small and large forms of latent transforming growth factor-beta in a chemically defined system

1 reference

https://pubmed.ncbi.nlm.nih.gov/22700773

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiogenesis in pituitary adenomas - relationship to endocrine function, treatment and outcome

1 reference

https://pubmed.ncbi.nlm.nih.gov/22700773

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based on heuristic

inferred from PubMed ID database lookup

ABT-898 induces tumor regression and prolongs survival in a mouse model of epithelial ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22700773

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of angiogenesis in 77 pituitary adenomas using endoglin as a marker

1 reference

https://pubmed.ncbi.nlm.nih.gov/22700773

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1210/EN.2012-1007

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

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