Modulation of the pancreatic islet beta-cell-delayed rectifier potassium channel Kv2.1 by the polyunsaturated fatty acid arachidonate. (Q36097172)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17197450 AND SRC:MED&resulttype=core&format=json

23 December 2019

title

Modulation of the pancreatic islet beta-cell-delayed rectifier potassium channel Kv2.1 by the polyunsaturated fatty acid arachidonate (English)

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23 December 2019

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2

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23 December 2019

Shunzhong S Bao

3

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23 December 2019

author name string

David A Jacobson

1

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23 December 2019

John Turk

4

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23 December 2019

Louis H Philipson

5

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23 December 2019

language of work or name

English

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publication date

29 December 2006

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23 December 2019

number of pages

8

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Journal of Biological Chemistry

inferred from page(s)

published in

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23 December 2019

volume

282

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23 December 2019

issue

10

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23 December 2019

page(s)

7442-7449

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AKAP signaling complexes: getting to the heart of the matter

23 December 2019

cites work

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The human Kv1.1 channel is palmitoylated, modulating voltage sensing: Identification of a palmitoylation consensus sequence

2 October 2017

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Pancreatic islets and insulinoma cells express a novel isoform of group VIA phospholipase A2 (iPLA2 beta) that participates in glucose-stimulated insulin secretion and is not produced by alternate splicing of the iPLA2 beta transcript

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Arachidonic acid, palmitic acid and glucose are important for the modulation of clonal pancreatic beta-cell insulin secretion, growth and functional integrity

2 October 2017

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The phosphatidylinositol 3-kinase inhibitor LY294002 potently blocks K(V) currents via a direct mechanism

2 October 2017

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Identification of calcium-independent phospholipase A2 (iPLA2) beta, and not iPLA2gamma, as the mediator of arginine vasopressin-induced arachidonic acid release in A-10 smooth muscle cells. Enantioselective mechanism-based discrimination of mammali

2 October 2017

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Members of the Kv1 and Kv2 voltage-dependent K( ) channel families regulate insulin secretion

2 October 2017

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Human Pancreatic Islets Express mRNA Species Encoding Two Distinct Catalytically Active Isoforms of Group VI Phospholipase A2 (iPLA2) [etc.]

2 October 2017

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Pancreatic islets express a Ca2 -independent phospholipase A2 enzyme that contains a repeated structural motif homologous to the integral membrane protein binding domain of ankyrin

2 October 2017

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Expression and function of pancreatic beta-cell delayed rectifier K channels. Role in stimulus-secretion coupling

2 October 2017

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K channels: generating excitement in pancreatic beta-cells

2 October 2017

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Mass spectrometric identification and quantitation of arachidonate-containing phospholipids in pancreatic islets: prominence of plasmenylethanolamine molecular species

2 October 2017

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2 October 2017

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2 October 2017

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Concomitant acceleration of the activation and inactivation kinetics of the human delayed rectifier K channel (Kv1.1) by Ca(2 )-independent phospholipase A2.

2 October 2017

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ATP-sensitive K channel modulation by products of PLA2 action in the insulin-secreting HIT cell line

2 October 2017

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2 October 2017

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The role of phospholipid-derived mediators including arachidonic acid, its metabolites, and inositoltrisphosphate and of intracellular Ca2 in glucose-induced insulin secretion by pancreatic islets

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2 October 2017

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Secretory phospholipase A2 is released from pancreatic β-cells and stimulates insulin secretion via inhibition of ATP-dependent K channels

2 July 2018

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Electrospray Ionization Mass Spectrometric Analyses of Phospholipids from Rat and Human Pancreatic Islets and Subcellular Membranes: Comparison to Other Tissues and Implications for Membrane Fusion in Insulin Exocytosis

2 July 2018

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Fatty acid ethyl esters, nonoxidative metabolites of ethanol, accelerate the kinetics of activation of the human brain delayed rectifier K channel, Kv1.1.

2 July 2018

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Arachidonic acid metabolism in isolated pancreatic islets. IV. Negative ion-mass spectrometric quantitation of monooxygenase product synthesis by liver and islets

2 July 2018

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Glucose-induced accumulation of inositol trisphosphates in isolated pancreatic islets. Predominance of the 1,3,4-isomer

2 July 2018

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Unmasking of arachidonate-induced insulin release by removal of extracellular calcium. Arachidonic acid mobilizes cellular calcium in rat islets of Langerhans

2 July 2018

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Studies on the mechanism of inhibition of glucose-stimulated insulin secretion by noradrenaline in rat islets of Langerhans

2 July 2018

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The effects of fatty acids on phosphoinositide synthesis and myo-inositol accumulation in exocrine pancreas.

2 July 2018

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Arachidonic acid affects membrane ionic conductances of GH3 pituitary cells

2 July 2018

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Characterization of a delayed rectifier K channel in NG108-15 neuroblastoma X glioma cells: gating kinetics and the effects of enrichment of membrane phospholipids with arachidonic acid

2 July 2018

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Fatty acid composition of serum cholesterol esters in different degrees of glucose intolerance: a population-based study.

2 July 2018

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Inhibition of phospholipase A2 and insulin secretion in pancreatic islets

2 July 2018

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Arachidonic acid metabolism in isolated pancreatic islets. VI. Carbohydrate insulin secretagogues must be metabolized to induce eicosanoid release

2 July 2018

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Carbachol stimulation of phospholipase A2 and insulin secretion in pancreatic islets

2 July 2018

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Reduction in voltage-gated K currents in primary cultured rat pancreatic beta-cells by linoleic acids

2 July 2018

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Functional conversion between A-type and delayed rectifier K channels by membrane lipids

23 September 2018

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A novel mechanism for the store-operated calcium influx pathway

23 September 2018

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Inhibition of Kv2.1 voltage-dependent K channels in pancreatic beta-cells enhances glucose-dependent insulin secretion.

23 September 2018

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23 September 2018

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Linoleic acid both enhances activation and blocks Kv1.5 and Kv2.1 channels by two separate mechanisms

23 September 2018

1 reference

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Studies of phospholipid metabolism, proliferation, and secretion of stably transfected insulinoma cells that overexpress group VIA phospholipase A2.

23 September 2018

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Delayed rectifier K channel overexpression in transgenic islets and beta-cells associated with impaired glucose responsiveness.

23 September 2018

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Arachidonic acid metabolism in isolated pancreatic islets. I. Identification and quantitation of lipoxygenase and cyclooxygenase products.

23 September 2018

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Evidence for association of an ATP-stimulatable Ca(2 )-independent phospholipase A2 from pancreatic islets and HIT insulinoma cells with a phosphofructokinase-like protein

23 September 2018

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12 December 2020

Glucose-responsitivity and expression of an ATP-stimulatable, Ca(2 )-independent phospholipase A2 enzyme in clonal insulinoma cell lines

1 reference

12 December 2020

Characterization of a Ca2 release-activated nonselective cation current regulating membrane potential and [Ca2 ]i oscillations in transgenically derived beta-cells

1 reference

12 December 2020

Glucose decreases Na ,K -ATPase activity in pancreatic beta-cells. An effect mediated via Ca2 -independent phospholipase A2 and protein kinase C-dependent phosphorylation of the alpha-subunit

1 reference

12 December 2020

Studies of the role of group VI phospholipase A2 in fatty acid incorporation, phospholipid remodeling, lysophosphatidylcholine generation, and secretagogue-induced arachidonic acid release in pancreatic islets and insulinoma cells

1 reference

12 December 2020

Electrospray ionization/mass spectrometric analyses of human promonocytic U937 cell glycerolipids and evidence that differentiation is associated with membrane lipid composition changes that facilitate phospholipase A2 activation

1 reference

12 December 2020

Studies of insulin secretory responses and of arachidonic acid incorporation into phospholipids of stably transfected insulinoma cells that overexpress group VIA phospholipase A2 (iPLA2beta ) indicate a signaling rather than a housekeeping role for

1 reference

12 December 2020

Fatty acid incorporation into phospholipids of isolated pancreatic islets of the rat. Relationship to insulin release

1 reference

12 December 2020

Secretogogue-stimulated phosphatidylinositol breakdown in the exocrine pancreas liberates arachidonic acid, stearic acid, and glycerol by sequential actions of phospholipase C and diglyceride lipase

1 reference

12 December 2020

Intracellular Ca2 mobilization by arachidonic acid. Comparison with myo-inositol 1,4,5-trisphosphate in isolated pancreatic islets

1 reference

12 December 2020

Arachidonic acid metabolism and insulin secretion by isolated human pancreatic islets

1 reference

12 December 2020

Tedisamil blocks the transient and delayed rectifier K currents in mammalian cardiac and glial cells

1 reference

12 December 2020

Fatty acid composition of serum lipids and erythrocyte membranes in type 2 (non-insulin-dependent) diabetic men

1 reference

12 December 2020

Free fatty acid accumulation in secretagogue-stimulated pancreatic islets and effects of arachidonate on depolarization-induced insulin secretion

1 reference

12 December 2020

Arachidonic acid induces an increase in the cytosolic calcium concentration in single pancreatic islet beta cells

1 reference

12 December 2020

Inhibition of arachidonate release by secretagogue-stimulated pancreatic islets suppresses both insulin secretion and the rise in beta-cell cytosolic calcium ion concentration

1 reference

12 December 2020

Mass spectrometric characterization of arachidonate-containing plasmalogens in human pancreatic islets and in rat islet beta-cells and subcellular membranes

1 reference

12 December 2020

Characterization of an ATP-stimulatable Ca(2 )-independent phospholipase A2 from clonal insulin-secreting HIT cells and rat pancreatic islets: a possible molecular component of the beta-cell fuel sensor

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M607858200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17197450 AND SRC:MED&resulttype=core&format=json

23 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17197450 AND SRC:MED&resulttype=core&format=json

23 December 2019

PubMed publication ID

17197450

1 reference