Berardinelli-Seip congenital lipodystrophy 2 regulates adipocyte lipolysis, browning, and energy balance in adult animals. (Q36093189)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26269358 AND SRC:MED&resulttype=core&format=json

22 February 2020

title

Berardinelli-Seip congenital lipodystrophy 2 regulates adipocyte lipolysis, browning, and energy balance in adult animals (English)

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22 February 2020

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9

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22 February 2020

author name string

Hongyi Zhou

1

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22 February 2020

Xinnuo Lei

2

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22 February 2020

Tyler Benson

3

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22 February 2020

James Mintz

4

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22 February 2020

Xiaojing Xu

5

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22 February 2020

Ruth B Harris

6

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22 February 2020

Neal L Weintraub

7

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22 February 2020

Xiaoling Wang

8

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22 February 2020

language of work or name

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12 August 2015

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Journal of Lipid Research

22 February 2020

published in

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22 February 2020

volume

56

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22 February 2020

issue

10

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22 February 2020

page(s)

1912-1925

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Seipin is necessary for normal brain development and spermatogenesis in addition to adipogenesis

22 February 2020

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Seipin oligomers can interact directly with AGPAT2 and lipin 1, physically scaffolding critical regulators of adipogenesis

2 October 2017

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Altered miRNA processing disrupts brown/white adipocyte determination and associates with lipodystrophy

2 October 2017

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2 October 2017

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2 October 2017

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Lipolytic products activate peroxisome proliferator-activated receptor (PPAR) α and δ in brown adipocytes to match fatty acid oxidation with supply

2 October 2017

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Berardinelli-seip congenital lipodystrophy 2/seipin is a cell-autonomous regulator of lipolysis essential for adipocyte differentiation

2 October 2017

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Molecular characterization of seipin and its mutants: implications for seipin in triacylglycerol synthesis

2 October 2017

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A role for phosphatidic acid in the formation of "supersized" lipid droplets

2 October 2017

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beta3-adrenergic receptor induction of adipocyte inflammation requires lipolytic activation of stress kinases p38 and JNK

2 October 2017

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SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

2 October 2017

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Recruitment of brown fat and conversion of white into brown adipocytes: strategies to fight the metabolic complications of obesity?

2 October 2017

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Human PTRF mutations cause secondary deficiency of caveolins resulting in muscular dystrophy with generalized lipodystrophy

2 October 2017

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The human lipodystrophy gene product Berardinelli-Seip congenital lipodystrophy 2/seipin plays a key role in adipocyte differentiation

2 October 2017

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Minireview: Pref-1: role in adipogenesis and mesenchymal cell fate

2 October 2017

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Molecular mechanisms of hepatic steatosis and insulin resistance in the AGPAT2-deficient mouse model of congenital generalized lipodystrophy

2 October 2017

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AdPLA ablation increases lipolysis and prevents obesity induced by high-fat feeding or leptin deficiency

2 October 2017

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FSP27 contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular lipid droplets

2 October 2017

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Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast

2 October 2017

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The lipodystrophy protein seipin is found at endoplasmic reticulum lipid droplet junctions and is important for droplet morphology

2 October 2017

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PPARalpha activators and fasting induce the expression of adipose differentiation-related protein in liver

2 October 2017

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2 October 2017

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2 October 2017

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A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

2 October 2017

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2 October 2017

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Congenital generalized lipodystrophy: significance of triglyceride biosynthetic pathways

2 October 2017

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2 October 2017

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betaAR signaling required for diet-induced thermogenesis and obesity resistance

2 October 2017

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AGPAT2 is mutated in congenital generalized lipodystrophy linked to chromosome 9q34.

2 October 2017

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Identification of the gene altered in Berardinelli-Seip congenital lipodystrophy on chromosome 11q13.

2 October 2017

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Phospholipid biosynthesis in the yeast Saccharomyces cerevisiae and interrelationship with other metabolic processes

2 October 2017

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A gene for congenital generalized lipodystrophy maps to human chromosome 9q34.

2 October 2017

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Adipose differentiation-related protein is an ubiquitously expressed lipid storage droplet-associated protein

2 October 2017

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Generalized lipodystrophy, congenital and acquired (lipoatrophy).

2 October 2017

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The beta 3-adrenergic receptor inhibits insulin-stimulated leptin secretion from isolated rat adipocytes

2 October 2017

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2 October 2017

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Acute cold-induced suppression of ob (obese) gene expression in white adipose tissue of mice: mediation by the sympathetic system

2 October 2017

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Thiazolidinediones partially reverse the metabolic disturbances observed in Bscl2/seipin-deficient mice

2 October 2017

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2 July 2018

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2 July 2018

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2 July 2018

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2 July 2018

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2 July 2018

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Molecular mechanisms underlying fasting modulated liver insulin sensitivity and metabolism in male lipodystrophic Bscl2/Seipin-deficient mice.

2 July 2018

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Adipose-specific knockout of SEIPIN/BSCL2 results in progressive lipodystrophy.

23 September 2018

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A role for seipin in lipid droplet dynamics and inheritance in yeast

23 September 2018

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Seipin ablation in mice results in severe generalized lipodystrophy

23 September 2018

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23 September 2018

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Association of a homozygous nonsense caveolin-1 mutation with Berardinelli-Seip congenital lipodystrophy.

23 September 2018

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Norepinephrine increases glucose transport in brown adipocytes via beta3-adrenoceptors through a cAMP, PKA, and PI3-kinase-dependent pathway stimulating conventional and novel PKCs.

23 September 2018

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23 September 2018

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A Gene for Congenital Generalized Lipodystrophy Maps to Human Chromosome 9q34

23 September 2018

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Activation of beta(3) adrenergic receptors suppresses leptin expression and mediates a leptin-independent inhibition of food intake in mice

23 September 2018

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The effect of intermittent cold treatment on the adipose tissue of the cat. Apparent transformation from white to brown adipose tissue.

23 September 2018

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12 December 2020

Control of beta 3-adrenergic receptor gene expression in brown adipocytes in culture.

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Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine

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Genetic basis of congenital generalized lipodystrophy

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Identifiers

DOI

10.1194/JLR.M060244

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26269358 AND SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26269358 AND SRC:MED&resulttype=core&format=json

22 February 2020

PubMed publication ID

26269358

1 reference