Protein tyrosine phosphatase receptor delta acts as a neuroblastoma tumor suppressor by destabilizing the aurora kinase A oncogene. (Q36092374)

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22 January 2020

title

Protein tyrosine phosphatase receptor delta acts as a neuroblastoma tumor suppressor by destabilizing the aurora kinase A oncogene (English)

1 reference

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22 January 2020

1 reference

6

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22 January 2020

Derek Murphy

7

1 reference

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22 January 2020

author name string

Maria Meehan

1

1 reference

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22 January 2020

Laavanya Parthasarathi

2

1 reference

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22 January 2020

Niamh Moran

3

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22 January 2020

Caroline A Jefferies

4

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22 January 2020

Niamh Foley

5

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22 January 2020

Jacqueline Ryan

8

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22 January 2020

Berenice Ortiz

9

1 reference

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22 January 2020

Armida W M Fabius

10

1 reference

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22 January 2020

Timothy A Chan

11

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22 January 2020

Raymond L Stallings

12

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22 January 2020

publication date

5 February 2012

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22 January 2020

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22 January 2020

volume

11

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22 January 2020

page(s)

6

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SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphase

22 January 2020

cites work

1 reference

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Dissection of the oncogenic MYCN transcriptional network reveals a large set of clinically relevant cell cycle genes as drivers of neuroblastoma tumorigenesis

2 October 2017

1 reference

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Efficacy and pharmacokinetic/pharmacodynamic evaluation of the Aurora kinase A inhibitor MLN8237 against preclinical models of pediatric cancer.

2 October 2017

1 reference

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High resolution ArrayCGH and expression profiling identifies PTPRD and PCDH17/PCH68 as tumor suppressor gene candidates in laryngeal squamous cell carcinoma.

2 October 2017

1 reference

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Polo-like kinase 1 is a therapeutic target in high-risk neuroblastoma

2 October 2017

1 reference

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Shared and separate functions of polo-like kinases and aurora kinases in cancer

2 October 2017

1 reference

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Initial testing of the aurora kinase A inhibitor MLN8237 by the Pediatric Preclinical Testing Program (PPTP).

2 October 2017

1 reference

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A catalog of genes homozygously deleted in human lung cancer and the candidacy of PTPRD as a tumor suppressor gene.

2 October 2017

1 reference

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Global MYCN transcription factor binding analysis in neuroblastoma reveals association with distinct E-box motifs and regions of DNA hypermethylation

2 October 2017

1 reference

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Distinct high-profile methylated genes in colorectal cancer

2 October 2017

1 reference

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Aurora A is a negative prognostic factor and a new therapeutic target in human neuroblastoma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395855

The tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancers

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395855

Stabilization of N-Myc is a critical function of Aurora A in human neuroblastoma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395855

Mutational inactivation of PTPRD in glioblastoma multiforme and malignant melanoma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395855

Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395855

Aberrant splicing of the PTPRD gene mimics microdeletions identified at this locus in neuroblastomas

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395855

Constitutive phosphorylation of aurora-a on ser51 induces its stabilization and consequent overexpression in cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395855

Allelic imbalances and microdeletions affecting the PTPRD gene in cutaneous squamous cell carcinomas detected using single nucleotide polymorphism microarray analysis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395855

High-resolution analysis of chromosomal breakpoints and genomic instability identifies PTPRD as a candidate tumor suppressor gene in neuroblastoma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395855

Protein kinases controlling the onset of mitosis.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395855

Identification of chromosome arm 9p as the most frequent target of homozygous deletions in lung cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395855

Aurora-A site specificity: a study with synthetic peptide substrates

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395855

Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395855

Aurora A, meiosis and mitosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395855

Neuroblastoma: biological insights into a clinical enigma

2 October 2017

1 reference

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MIM-B, a putative metastasis suppressor protein, binds to actin and to protein tyrosine phosphatase delta

2 October 2017

1 reference

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The LAR/PTP delta/PTP sigma subfamily of transmembrane protein-tyrosine-phosphatases: multiple human LAR, PTP delta, and PTP sigma isoforms are expressed in a tissue-specific manner and associate with the LAR-interacting protein LIP.1

2 October 2017

1 reference

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Molecular characterization of the human transmembrane protein-tyrosine phosphatase delta. Evidence for tissue-specific expression of alternative human transmembrane protein-tyrosine phosphatase delta isoforms

2 October 2017

1 reference

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Receptor tyrosine phosphatase-delta is a homophilic, neurite-promoting cell adhesion molecular for CNS neurons.

2 October 2017

1 reference

Crossref

https://api.crossref.org/works/10.1186/1476-4598-11-6

Genome-wide loss of heterozygosity and copy number analysis in melanoma using high-density single-nucleotide polymorphism arrays.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186/1476-4598-11-6

Phospho-regulation of human protein kinase Aurora-A: analysis using anti-phospho-Thr288 monoclonal antibodies

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22305495

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22305495

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1476-4598-11-6

1 reference

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Dimensions Publication ID

22 January 2020

1022655269

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Fatcat ID

release_m4j6xv7kwzcybpmvapxoipivni

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Fatcat

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mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

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22 January 2020

PubMed publication ID

22305495

1 reference

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