Potential Effects of Phytoestrogen Genistein in Modulating Acute Methotrexate Chemotherapy-Induced Osteoclastogenesis and Bone Damage in Rats. (Q36088558)

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English	Potential Effects of Phytoestrogen Genistein in Modulating Acute Methotrexate Chemotherapy-Induced Osteoclastogenesis and Bone Damage in Rats.	scientific article

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22 February 2020

Potential Effects of Phytoestrogen Genistein in Modulating Acute Methotrexate Chemotherapy-Induced Osteoclastogenesis and Bone Damage in Rats (English)

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22 February 2020

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Tristan J. King

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22 February 2020

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22 February 2020

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22 February 2020

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Tetyana Shandala

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22 February 2020

Alice M Lee

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22 February 2020

Bruce K Foster

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22 February 2020

Ke-Ming Chen

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22 February 2020

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6 August 2015

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22 February 2020

International Journal of Molecular Sciences

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22 February 2020

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22 February 2020

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22 February 2020

18293-18311

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22 February 2020

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6 August 2015

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Supplementation with fish oil and genistein, individually or in combination, protects bone against the adverse effects of methotrexate chemotherapy in rats

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Phytoestrogens directly inhibit TNF-α-induced bone resorption in RAW264.7 cells by suppressing c-fos-induced NFATc1 expression

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Protective effect of genistein aglycone on the development of osteonecrosis of the femoral head and secondary osteoporosis induced by methylprednisolone in rats

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Genistein aglycone reverses glucocorticoid-induced osteoporosis and increases bone breaking strength in rats: a comparative study with alendronate

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Effects of genistein aglycone in osteoporotic, ovariectomized rats: a comparison with alendronate, raloxifene and oestradiol

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Soy isoflavones avert chronic inflammation-induced bone loss and vascular disease

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The effects of methotrexate (MTX) on bone. A densitometric study conducted on 59 patients with MTX administered at different doses

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11 July 2018

Attenuated Wnt/β-catenin signalling mediates methotrexate chemotherapy-induced bone loss and marrow adiposity in rats

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23 September 2018

Effects of isoflavones equol and genistein on bone quality in a rat osteopenia model

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23 September 2018

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23 September 2018

Comparison of the bone protective effects of an isoflavone-rich diet with dietary and subcutaneous administrations of genistein in ovariectomized rats

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23 September 2018

Damaging effects of chronic low-dose methotrexate usage on primary bone formation in young rats and potential protective effects of folinic acid supplementary treatment.

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Breast safety and efficacy of genistein aglycone for postmenopausal bone loss: a follow-up study.

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23 September 2018

Effects of genistein on vertebral trabecular bone microstructure, bone mineral density, microcracks, osteocyte density, and bone strength in ovariectomized rats

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23 September 2018

OPG and sRANKL serum concentrations in osteopenic, postmenopausal women after 2-year genistein administration

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23 September 2018

Genistein stimulates osteoblastic differentiation via p38 MAPK-Cbfa1 pathway in bone marrow culture

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23 September 2018

Effects of the phytoestrogen genistein on bone metabolism in osteopenic postmenopausal women: a randomized trial

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23 September 2018

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23 September 2018

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23 September 2018

The soy isoflavone genistein decreases adipose deposition in mice

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Genistein prevents bone resorption diseases by inhibiting bone resorption and stimulating bone formation

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23 September 2018

Effects of genistein and hormone-replacement therapy on bone loss in early postmenopausal women: a randomized double-blind placebo-controlled study

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23 September 2018

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23 September 2018

Cytokine production by macrophages in association with phagocytosis of etoposide-treated P388 cells in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581246

23 September 2018

Bone mineral decrements in survivors of childhood acute lymphoblastic leukemia: frequency of occurrence and risk factors for their development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4581246

23 September 2018

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1 reference

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23 September 2018

Effects of Intensive Chemotherapy on Bone and Collagen Turnover and the Growth Hormone Axis in Children with Acute Lymphoblastic Leukemia

1 reference

https://api.crossref.org/works/10.3390/IJMS160818293

21 January 2018

Bone Turnover and Growth During and After Continuing Chemotherapy in Children with Acute Lymphoblastic Leukemia

1 reference

https://api.crossref.org/works/10.3390/IJMS160818293

21 January 2018

Methotrexate chemotherapy reduces osteogenesis but increases adipogenic potential in the bone marrow

1 reference

https://api.crossref.org/works/10.3390/IJMS160818293

21 January 2018

Methotrexate Chemotherapy Promotes Osteoclast Formation in the Long Bone of Rats via Increased Pro-Inflammatory Cytokines and Enhanced NF-κB Activation

1 reference

https://api.crossref.org/works/10.3390/IJMS160818293

21 January 2018

Effects of intensive chemotherapy on bone and collagen turnover and the growth hormone axis in children with acute lymphoblastic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/26258775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bone mineral assessment with tibial ultrasonometry and dual-energy X-ray absorptiometry in long-term survivors of acute lymphoblastic leukemia in childhood

1 reference

https://pubmed.ncbi.nlm.nih.gov/26258775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The phytoestrogen genistein reduces bone loss in short-term ovariectomized rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/26258775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The short- and long-term effects of methotrexate on the rat skeleton

1 reference

https://pubmed.ncbi.nlm.nih.gov/26258775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory effect of genistein on bone resorption in tissue culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/26258775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular mechanisms for methotrexate chemotherapy-induced bone growth defects

1 reference

https://pubmed.ncbi.nlm.nih.gov/26258775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bone mineral density in survivors of childhood acute lymphoblastic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/26258775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bone mineral density in long-term survivors of highly malignant osteosarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/26258775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Skeletal morbidity in childhood acute lymphoblastic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/26258775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anabolic effect of genistein in osteoblastic MC3T3-E1 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/26258775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Folinic acid attenuates methotrexate chemotherapy-induced damages on bone growth mechanisms and pools of bone marrow stromal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/26258775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of chemotherapeutic agents on bone. I. Short-term methotrexate and doxorubicin (adriamycin) treatment in a rat model

1 reference

https://pubmed.ncbi.nlm.nih.gov/26258775

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.3390/IJMS160818293

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22 February 2020

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22 February 2020

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22 February 2020

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