De novo DNA methylation is required to restrict T helper lineage plasticity (Q36080339)

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1 February 2020

title

De novo DNA methylation is required to restrict T helper lineage plasticity (English)

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1 February 2020

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2

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1 February 2020

author name string

Rajan M Thomas

1

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1 February 2020

Brian H Ladle

3

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1 February 2020

Jonathan D Powell

4

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1 February 2020

Andrew D Wells

5

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1 February 2020

language of work or name

English

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publication date

14 May 2012

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Journal of Biological Chemistry

1 February 2020

published in

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1 February 2020

volume

287

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1 February 2020

issue

27

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1 February 2020

page(s)

22900-22909

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Histone tails regulate DNA methylation by allosterically activating de novo methyltransferase.

1 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391093

Molecular coupling of DNA methylation and histone methylation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391093

Fate mapping of IL-17-producing T cells in inflammatory responses

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391093

Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX-DNMT3-DNMT3L domain

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391093

Identification of DNA methyltransferase 3a as a T cell receptor-induced regulator of Th1 and Th2 differentiation.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391093

Linking DNA methylation and histone modification: patterns and paradigms

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391093

Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391093

Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4 T cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391093

Late developmental plasticity in the T helper 17 lineage

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391093

T-bet dependent removal of Sin3A-histone deacetylase complexes at the Ifng locus drives Th1 differentiation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391093

Genome-scale DNA methylation maps of pluripotent and differentiated cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391093

Long-range regulation of cytokine gene expression.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391093

DNA methylation dictates histone H3K4 methylation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391093

Inhibition of IFN-gamma transcription by site-specific methylation during T helper cell development

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391093

A bivalent chromatin structure marks key developmental genes in embryonic stem cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391093

Polycomb complexes repress developmental regulators in murine embryonic stem cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391093

T-bet antagonizes mSin3a recruitment and transactivates a fully methylated IFN-gamma promoter via a conserved T-box half-site

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391093

An epigenetic view of helper T cell differentiation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391093

Hlx is induced by and genetically interacts with T-bet to promote heritable T(H)1 gene induction

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391093

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391093

Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391093

Reversibility of T helper 1 and 2 populations is lost after long-term stimulation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391093

Differentiation of the T helper phenotypes by analysis of the methylation state of the IFN-gamma gene

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391093

A distinct region of the murine IFN-gamma promoter is hypomethylated from early T cell development through mature naive and Th1 cell differentiation, but is hypermethylated in Th2 cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391093

Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets.

11 July 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111.312785

A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111.312785

Independent and epigenetic regulation of the interleukin-4 alleles in CD4 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111.312785

Interferons direct Th2 cell reprogramming to generate a stable GATA-3( )T-bet( ) cell subset with combined Th2 and Th1 cell functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111.312785

Human Th1 and Th17 cells exhibit epigenetic stability at signature cytokine and transcription factor loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111.312785

The Proximal Regulatory Element of the Interferon-γ Promoter Mediates Selective Expression in T Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M111.312785

DNA methylation is a nonredundant repressor of the Th2 effector program

21 January 2018

1 reference

12 December 2020

Signals from CD28 induce stable epigenetic modification of the IL-2 promoter

1 reference

12 December 2020

Role of DNA Methylation in Stable Gene Repression

1 reference

12 December 2020

Superantigen-induced CD4 T cell tolerance is associated with DNA methylation and histone hypo-acetylation at cytokine gene loci

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M111.312785

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22584578 AND SRC:MED&resulttype=core&format=json

1 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22584578 AND SRC:MED&resulttype=core&format=json

1 February 2020

PubMed publication ID

22584578

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22584578 AND SRC:MED&resulttype=core&format=json