RAC-LATS1/2 signaling regulates YAP activity by switching between the YAP-binding partners TEAD4 and RUNX3. (Q36079567)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27425596 AND SRC:MED&resulttype=core&format=json

18 March 2020

title

RAC-LATS1/2 signaling regulates YAP activity by switching between the YAP-binding partners TEAD4 and RUNX3 (English)

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18 March 2020

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GOA release 2020-03-11

author

Sang-Cheol Bae

11

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18 March 2020

author name string

J-W Jang

1

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18 March 2020

M-K Kim

2

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18 March 2020

Y-S Lee

3

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18 March 2020

J-W Lee

4

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18 March 2020

D-M Kim

5

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18 March 2020

S-H Song

6

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18 March 2020

J-Y Lee

7

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18 March 2020

B-Y Choi

8

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18 March 2020

B Min

9

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18 March 2020

X-Z Chi

10

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18 March 2020

language of work or name

English

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publication date

18 July 2016

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18 March 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27425596 AND SRC:MED&resulttype=core&format=json

18 March 2020

volume

36

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18 March 2020

issue

7

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18 March 2020

page(s)

999-1011

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The RUNX family: developmental regulators in cancer

18 March 2020

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Causal relationship between the loss of RUNX3 expression and gastric cancer

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RUNX3 is a novel negative regulator of oncogenic TEAD-YAP complex in gastric cancer

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Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma

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Runt and Lozenge function in Drosophila development

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Tao-1 Phosphorylates Hippo/MST Kinases to Regulate the Hippo-Salvador-Warts Tumor Suppressor Pathway

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The sterile 20-like kinase Tao-1 controls tissue growth by regulating the Salvador-Warts-Hippo pathway

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Elucidation of a universal size-control mechanism in Drosophila and mammals

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Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

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In vivo regulation of Yorkie phosphorylation and localization.

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Hippo signaling regulates Yorkie nuclear localization and activity through 14-3-3 dependent and independent mechanisms

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SCALLOPED interacts with YORKIE, the nuclear effector of the hippo tumor-suppressor pathway in Drosophila

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The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway

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The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control

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TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm

21 January 2018

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Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription

21 January 2018

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TEAD mediates YAP-dependent gene induction and growth control

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A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator

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Energy-dependent regulation of cell structure by AMP-activated protein kinase

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A modular misexpression screen in Drosophila detecting tissue-specific phenotypes

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Identification of Serum-Derived Sphingosine-1-Phosphate as a Small Molecule Regulator of YAP

21 January 2018

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Serum deprivation inhibits the transcriptional co-activator YAP and cell growth via phosphorylation of the 130-kDa isoform of Angiomotin by the LATS1/2 protein kinases

21 January 2018

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Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway

21 January 2018

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Hippo-independent activation of YAP by the GNAQ uveal melanoma oncogene through a trio-regulated rho GTPase signaling circuitry.

21 January 2018

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Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility

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Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase

31 March 2020

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PubMed

https://pubmed.ncbi.nlm.nih.gov/27425596

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Lozenge is expressed in pluripotent precursor cells and patterns multiple cell types in the Drosophila eye through the control of cell-specific transcription factors.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27425596

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2016.266

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27425596 AND SRC:MED&resulttype=core&format=json

18 March 2020

1 reference