The enigma of CD4‐lineage specification (Q36073462)

12 August 2017

1 reference

title

The enigma of CD4-lineage specification (English)

1 reference

12 August 2017

The enigma of CD4‐lineage specification (English)

1 reference

https://api.crossref.org/works/10.1002/EJI.201041098

25 November 2024

author name string

Yumei Xiong

series ordinal

1

1 reference

12 August 2017

Rémy Bosselut

series ordinal

2

1 reference

12 August 2017

language of work or name

English

0 references

publication date

10 February 2011

1 reference

full work available at URL

12 August 2017

https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/eji.201041098

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21341258

https://europepmc.org/articles/PMC3388806

25 November 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21341258

https://europepmc.org/articles/PMC3388806?pdf=render

25 November 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21341258

https://doi.org/10.1002/eji.201041098

25 November 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21341258

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002/eji.201041098

25 November 2024

1 reference

https://api.crossref.org/works/10.1002/EJI.201041098

https://onlinelibrary.wiley.com/doi/pdf/10.1002/eji.201041098

25 November 2024

1 reference

https://api.crossref.org/works/10.1002/EJI.201041098

European Journal of Immunology

25 November 2024

published in

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12 August 2017

41

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12 August 2017

3

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12 August 2017

568-574

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Shared dependence on the DNA-binding factor TOX for the development of lymphoid tissue–inducer cell and NK cell lineages

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

The sequential activity of Gata3 and Thpok is required for the differentiation of CD1d-restricted CD4 NKT cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

Decision checkpoints in the thymus

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

TCR-mediated ThPOK induction promotes development of mature (CD24-) gammadelta thymocytes.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

Tenuous paths in unexplored territory: From T cell receptor signaling to effector gene expression during thymocyte selection

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

Co-receptor choice by V alpha14i NKT cells is driven by Th-POK expression rather than avoidance of CD8-mediated negative selection

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

The zinc-finger protein MAZR is part of the transcription factor network that controls the CD4 versus CD8 lineage fate of double-positive thymocytes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

The transcription factor c-Myb primes CD4 CD8 immature thymocytes for selection into the iNKT lineage

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

Epigenetic propagation of CD4 expression is established by the Cd4 proximal enhancer in helper T cells.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

The role of ThPOK in control of CD4/CD8 lineage commitment

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

c-Myb promotes the survival of CD4 CD8 double-positive thymocytes through upregulation of Bcl-xL

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

Development of promyelocytic zinc finger and ThPOK-expressing innate gamma delta T cells is controlled by strength of TCR signaling and Id3.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

Foxp1 is an essential transcriptional regulator for the generation of quiescent naive T cells during thymocyte development.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

Gasp, a Grb2-associating protein, is critical for positive selection of thymocytes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

The cunning little vixen: Foxo and the cycle of life and death

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

CD4-CD8 lineage differentiation: Thpok-ing into the nucleus

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

A novel gene essential for the development of single positive thymocytes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

Themis controls thymocyte selection through regulation of T cell antigen receptor-mediated signaling

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

Themis, a T cell-specific protein important for late thymocyte development

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

E and ID proteins branch out.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

RUNX proteins in transcription factor networks that regulate T-cell lineage choice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

Thymic microenvironments for T-cell repertoire formation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

The zinc finger transcription factor Zbtb7b represses CD8-lineage gene expression in peripheral CD4 T cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

Lineage fate and intense debate: myths, models and mechanisms of CD4- versus CD8-lineage choice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4( ) T cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

The transcription factor PLZF directs the effector program of the NKT cell lineage

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

The BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

Notch signaling in CD4 and CD8 T cell development

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

Development of all CD4 T lineages requires nuclear factor TOX

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

Acquisition of a functional T cell receptor during T lymphocyte development is enforced by HEB and E2A transcription factors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

The transcription factor Zbtb7b promotes CD4 expression by antagonizing Runx-mediated activation of the CD4 silencer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

GATA3 controls the expression of CD5 and the T cell receptor during CD4 T cell lineage development

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

Expression of the transcription factor cKrox in peripheral CD8 T cells reveals substantial postthymic plasticity in CD4-CD8 lineage differentiation.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

GATA-3 regulates the development and function of invariant NKT cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

Kruppel-like factor 2 regulates thymocyte and T-cell migration

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

Critical functions for c-Myb at three checkpoints during thymocyte development

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

The chromatin remodeler Mi-2beta is required for CD4 expression and T cell development

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

TOX provides a link between calcineurin activation and CD8 lineage commitment

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

Critical roles for transcription factor GATA-3 in thymocyte development

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

Unraveling a revealing paradox: Why major histocompatibility complex I-signaled thymocytes "paradoxically" appear as CD4 8lo transitional cells during positive selection of CD8 T cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

Restricting Zap70 expression to CD4 CD8 thymocytes reveals a T cell receptor-dependent proofreading mechanism controlling the completion of positive selection

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

Positive and negative selection of T cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

TOX: an HMG box protein implicated in the regulation of thymocyte selection

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

Stepwise specification of lymphocyte developmental lineages.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

A heterodimer of HEB and an E12-related protein interacts with the CD4 enhancer and regulates its activity in T-cell lines

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

c-Krox, a transcriptional regulator of type I collagen gene expression, is preferentially expressed in skin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

CD8 is needed for development of cytotoxic T cells but not helper T cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

c-Myb regulates lineage choice in developing thymocytes via its target gene Gata3.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

Thymocyte selection is regulated by the helix-loop-helix inhibitor protein, Id3.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

Regulation of lineage commitment distinct from positive selection

27 July 2018

1 reference

https://api.crossref.org/works/10.1002/EJI.201041098

Cascading suppression of transcriptional silencers by ThPOK seals helper T cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/EJI.201041098

Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/EJI.201041098

GATA-3 expression is controlled by TCR signals and regulates CD4/CD8 differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/EJI.201041098

Gene expression profiling in mice with enforced Gata3 expression reveals putative targets of Gata3 in double positive thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/EJI.201041098

Sequential roles of Brg, the ATPase subunit of BAF chromatin remodeling complexes, in thymocyte development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/EJI.201041098

The regulation of the expression of gp39, the CD40 ligand, on normal and cloned CD4 T cells.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388806

Coreceptor reversal in the thymus: signaled CD4 8 thymocytes initially terminate CD8 transcription even when differentiating into CD8 T cells

23 September 2018

1 reference

12 December 2020

Epigenetic silencing of CD4 in T cells committed to the cytotoxic lineage

1 reference

12 December 2020

Expression of the transcription factor GATA-3 is required for the development of the earliest T cell progenitors and correlates with stages of cellular proliferation in the thymus

1 reference

12 December 2020

The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection

1 reference

12 December 2020

Identifiers

1 reference

12 August 2017

1 reference

12 August 2017

1 reference