Perforin and lymphohistiocytic proliferative disorders. (Q36065181)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15755277 AND SRC:MED&resulttype=core&format=json

9 January 2020

review article

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title

Perforin and lymphohistiocytic proliferative disorders (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15755277 AND SRC:MED&resulttype=core&format=json

9 January 2020

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15755277 AND SRC:MED&resulttype=core&format=json

9 January 2020

author name string

Jeffrey I Cohen

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15755277 AND SRC:MED&resulttype=core&format=json

9 January 2020

language of work or name

English

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publication date

1 March 2005

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15755277 AND SRC:MED&resulttype=core&format=json

British Journal of Haematology

9 January 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15755277 AND SRC:MED&resulttype=core&format=json

9 January 2020

volume

128

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15755277 AND SRC:MED&resulttype=core&format=json

9 January 2020

issue

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15755277 AND SRC:MED&resulttype=core&format=json

9 January 2020

page(s)

739-750

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15755277 AND SRC:MED&resulttype=core&format=json

HIV-specific CD8( ) T cells produce antiviral cytokines but are impaired in cytolytic function

9 January 2020

cites work

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Haemophagocytic lymphohistiocytosis: proposal of a diagnostic algorithm based on perforin expression

21 January 2018

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Regulation of antigen-specific CD8 T cell homeostasis by perforin and interferon-gamma.

21 January 2018

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Surface cathepsin B protects cytotoxic lymphocytes from self-destruction after degranulation

21 January 2018

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Identification of the homologous beige and Chediak-Higashi syndrome genes

21 January 2018

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Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid.

21 January 2018

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Aplastic anemia rescued by exhaustion of cytokine-secreting CD8 T cells in persistent infection with lymphocytic choriomeningitis virus

21 January 2018

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Cytosolic delivery of granzyme B by bacterial toxins: evidence that endosomal disruption, in addition to transmembrane pore formation, is an important function of perforin

21 January 2018

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Atypical features of familial hemophagocytic lymphohistiocytosis.

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Six novel mutations in the PRF1 gene in children with haemophagocytic lymphohistiocytosis

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Host response to EBV infection in X-linked lymphoproliferative disease results from mutations in an SH2-domain encoding gene

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SAP is required for generating long-term humoral immunity

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Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAP

21 January 2018

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Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B.

21 January 2018

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Induction of apoptosis and caspase activation in cells obtained from familial haemophagocytic lymphohistiocytosis patients

21 January 2018

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Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3).

21 January 2018

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Coxsackievirus B3-induced myocarditis: perforin exacerbates disease, but plays no detectable role in virus clearance

21 January 2018

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Spectrum of perforin gene mutations in familial hemophagocytic lymphohistiocytosis

21 January 2018

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Defective granule exocytosis in Rab27a-deficient lymphocytes from Ashen mice

21 January 2018

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Do CTL kill target cells by inducing apoptosis?

21 January 2018

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Polymerase chain reaction amplification of archival material for Epstein-Barr virus, cytomegalovirus, human herpesvirus 6, and parvovirus B19 in children with bone marrow hemophagocytosis

21 January 2018

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Clinical features and treatment strategies of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis

21 January 2018

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Modern management of children with haemophagocytic lymphohistiocytosis

21 January 2018

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An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8 T cells and interferon gamma are essential for the disorder

21 January 2018

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Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

21 January 2018

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Chronic active Epstein-Barr virus infection associated with mutations in perforin that impair its maturation

21 January 2018

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Preferential utilization of the perforin/granzyme pathway for lysis of Epstein-Barr virus-transformed lymphoblastoid cells by virus-specific CD4 T cells

21 January 2018

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Clinical and virologic characteristics of chronic active Epstein-Barr virus infection

21 January 2018

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Regulation of SLAM-mediated signal transduction by SAP, the X-linked lymphoproliferative gene product

21 January 2018

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Structure and function of human perforin

21 January 2018

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The ABCs of granule-mediated cytotoxicity: new weapons in the arsenal

21 January 2018

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No mutations of SAP/SH2D1A/DSHP and perforin genes in patients with Epstein-Barr virus-associated hemophagocytic syndrome in Japan

21 January 2018

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Mutations in RAB27A cause Griscelli syndrome associated with haemophagocytic syndrome

21 January 2018

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Cytotoxic cell granule-mediated apoptosis: perforin delivers granzyme B-serglycin complexes into target cells without plasma membrane pore formation

21 January 2018

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Characterisation of diverse PRF1 mutations leading to decreased natural killer cell activity in North American families with haemophagocytic lymphohistiocytosis

21 January 2018

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Identification and mutation analysis of the complete gene for Chediak-Higashi syndrome

21 January 2018

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Synergistic roles of granzymes A and B in mediating target cell death by rat basophilic leukemia mast cell tumors also expressing cytolysin/perforin

21 January 2018

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Patients with X-linked lymphoproliferative disease have a defect in 2B4 receptor-mediated NK cell cytotoxicity

21 January 2018

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Inactivating mutations in an SH2 domain-encoding gene in X-linked lymphoproliferative syndrome

21 January 2018

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Localization of a gene for familial hemophagocytic lymphohistiocytosis at chromosome 9q21.3-22 by homozygosity mapping

21 January 2018

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Overview and problematic standpoints of severe chronic active Epstein-Barr virus infection syndrome

21 January 2018

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Lymphocyte-mediated cytotoxicity.

21 January 2018

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The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM

21 January 2018

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Chronic Epstein-Barr virus infection associated with fever and interstitial pneumonitis. Clinical and serologic features and response to antiviral chemotherapy

21 January 2018

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A natural killer cell granule protein that induces DNA fragmentation and apoptosis

21 January 2018

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Perforin-mediated cytotoxicity is critical for surveillance of spontaneous lymphoma

21 January 2018

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Perforin gene defects in familial hemophagocytic lymphohistiocytosis.

21 January 2018

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The chronic mononucleosis syndrome

21 January 2018

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Perforin and interferon-gamma activities independently control tumor initiation, growth, and metastasis.

21 January 2018

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CD4( ) Epstein-Barr virus-specific cytotoxic T-lymphocytes from human umbilical cord blood

21 January 2018

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Oversecretion of IL-18 in haemophagocytic lymphohistiocytosis: a novel marker of disease activity

21 January 2018

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Increased serum levels of interferon-gamma-inducible protein 10 and monokine induced by gamma interferon in patients with haemophagocytic lymphohistiocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2141.2004.05305.X

Characteristic perforin gene mutations of haemophagocytic lymphohistiocytosis patients in Japan

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2141.2004.05305.X

Perforin is activated by a proteolytic cleavage during biosynthesis which reveals a phospholipid-binding C2 domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2141.2004.05305.X

Immunological control of murine gammaherpesvirus infection is independent of perforin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2141.2004.05305.X

The functional basis for hemophagocytic lymphohistiocytosis in a patient with co-inherited missense mutations in the perforin (PFN1) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2141.2004.05305.X

A mutation in Rab27a causes the vesicle transport defects observed in ashen mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2141.2004.05305.X

Epstein-Barr virus-specific T-cell cytotoxicity is mediated through the perforin pathway in patients with lymphoproliferative disorders after allogeneic bone marrow transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2141.2004.05305.X

Perforin is required for primary immunity to Histoplasma capsulatum

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2141.2004.05305.X

Functional consequences of perforin gene mutations in 22 patients with familial haemophagocytic lymphohistiocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2141.2004.05305.X

Most antiviral CD8 T cells during chronic viral infection do not express high levels of perforin and are not directly cytotoxic

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2141.2004.05305.X

Two distinct pathways of specific killing revealed by perforin mutant cytotoxic T lymphocytes

21 January 2018

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https://api.crossref.org/works/10.1111/J.1365-2141.2004.05305.X

New Paradigm for Lymphocyte Granule-mediated Cytotoxicity

21 January 2018

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https://api.crossref.org/works/10.1111/J.1365-2141.2004.05305.X