FTY720 suppresses interleukin-1beta-induced secretory phospholipase A2 expression in renal mesangial cells by a transcriptional mechanism (Q36052555)

11 August 2017

FTY720 suppresses interleukin-1beta-induced secretory phospholipase A2 expression in renal mesangial cells by a transcriptional mechanism (English)

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11 August 2017

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C Xin

1

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11 August 2017

S Ren

2

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11 August 2017

W Eberhardt

3

1 reference

11 August 2017

J Pfeilschifter

4

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11 August 2017

A Huwiler

5

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11 August 2017

language of work or name

English

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publication date

26 February 2007

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British Journal of Pharmacology

11 August 2017

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11 August 2017

150

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11 August 2017

7

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11 August 2017

943-950

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The immunosuppressant drug FTY720 inhibits cytosolic phospholipase A2 independently of sphingosine-1-phosphate receptors

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2013874

Post-transcriptional nucleotide modification and alternative folding of RNA

2 October 2017

1 reference

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The immunomodulator FTY720 and its phosphorylated derivative activate the Smad signalling cascade and upregulate connective tissue growth factor and collagen type IV expression in renal mesangial cells

2 October 2017

1 reference

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Role of histone acetylation in the control of gene expression

2 October 2017

1 reference

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Immunomodulator FTY720 Induces eNOS-dependent arterial vasodilatation via the lysophospholipid receptor S1P3.

2 October 2017

1 reference

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Overlapping signaling pathways of sphingosine 1-phosphate and TGF-beta in the murine Langerhans cell line XS52.

2 October 2017

1 reference

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Transforming growth factor-beta and Smad signalling in kidney diseases.

2 October 2017

1 reference

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2 October 2017

1 reference

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New immunosuppressants with potential implication in multiple sclerosis

2 October 2017

1 reference

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Involvement of Smad signaling in sphingosine 1-phosphate-mediated biological responses of keratinocytes

2 October 2017

1 reference

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New insights into TGF-beta-Smad signalling

2 October 2017

1 reference

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2 October 2017

1 reference

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Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

2 October 2017

1 reference

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Sphingosine-1-phosphate: an enigmatic signalling lipid

2 October 2017

1 reference

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SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7

2 October 2017

1 reference

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International Union of Pharmacology. XXXIV. Lysophospholipid receptor nomenclature

2 October 2017

1 reference

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The immune modulator FTY720 targets sphingosine 1-phosphate receptors

2 October 2017

1 reference

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Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists

2 October 2017

1 reference

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Physiology and pathophysiology of sphingolipid metabolism and signaling

2 October 2017

1 reference

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Extracellular nucleotides activate the p38-stress-activated protein kinase cascade in glomerular mesangial cells

2 October 2017

1 reference

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Sphingosine 1-phosphate: a prototype of a new class of second messengers.

2 October 2017

1 reference

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TGF-beta signal transduction

2 October 2017

1 reference

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FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats. I. FTY720 selectively decreases the number of circulating mature lymphocytes by acceleration of lymphocyte homing

2 October 2017

1 reference

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Sphingosine-1-Phosphate as a Ligand for the G Protein-Coupled Receptor EDG-1

2 October 2017

1 reference

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Cytokine-stimulated secretion of group II phospholipase A2 by rat mesangial cells. Its contribution to arachidonic acid release and prostaglandin synthesis by cultured rat glomerular cells

2 October 2017

1 reference

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The MAPK signaling cascade

2 October 2017

1 reference

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Cross-talk between transmembrane signalling systems: a prerequisite for the delicate regulation of glomerular haemodynamics by mesangial cells

2 October 2017

1 reference

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Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A

2 October 2017

1 reference

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Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation

2 October 2017

1 reference

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The pathobiology of the mesangium

2 October 2017

1 reference

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Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

2 October 2017

1 reference

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Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens

2 October 2017

1 reference

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Platelet-derived growth factor and angiotensin II stimulate the mitogen-activated protein kinase cascade in renal mesangial cells: comparison of hypertrophic and hyperplastic agonists

11 July 2018

1 reference

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Role of phospholipase C and protein kinase C in vasoconstrictor-induced prostaglandin synthesis in cultured rat renal mesangial cells

11 July 2018

1 reference

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Interleukin 1 and tumor necrosis factor synergistically stimulate prostaglandin synthesis and phospholipase A2 release from rat renal mesangial cells

11 July 2018

1 reference

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Transforming growth factor beta 2 differentially modulates interleukin-1 beta- and tumour-necrosis-factor-alpha-stimulated phospholipase A2 and prostaglandin E2 synthesis in rat renal mesangial cells

11 July 2018

1 reference

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Interleukin-1 beta, tumor necrosis factor and forskolin stimulate the synthesis and secretion of group II phospholipase A2 in rat mesangial cells

11 July 2018

1 reference

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Hypoxia increases group IIA phospholipase A(2) expression under inflammatory conditions in rat renal mesangial cells

11 July 2018

1 reference

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Selective lymphocyte inhibition by FTY720 slows the progressive course of chronic anti-thy 1 glomerulosclerosis

23 September 2018

1 reference

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Sphingosine 1-phosphate cross-activates the Smad signaling cascade and mimics transforming growth factor-beta-induced cell responses

23 September 2018

1 reference

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Sphingosine 1-phosphate (S1P) receptor subtypes S1P1 and S1P3, respectively, regulate lymphocyte recirculation and heart rate

23 September 2018

1 reference

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Amelioration of experimental autoimmune encephalomyelitis in Lewis rats by FTY720 treatment

23 September 2018

1 reference

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Signalling mechanisms in sphingosine 1-phosphate-promoted mesangial cell proliferation

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2013874

Activation-regulated expression and chemotactic function of sphingosine 1-phosphate receptors in mouse splenic T cells

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2013874

Effects of immunosuppressant FTY720 on renal and hepatic hemodynamics in the rat.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2013874

First human trial of FTY720, a novel immunomodulator, in stable renal transplant patients

23 September 2018

1 reference

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Potentiation of TNF-alpha-stimulated group IIA phospholipase A(2) expression by peroxisome proliferator-activated receptor alpha activators in rat mesangial cells.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2013874

Transforming growth factors type-beta and dexamethasone attenuate group II phospholipase A2 gene expression by interleukin-1 and forskolin in rat mesangial cells

23 September 2018

1 reference

12 December 2020

Interleukin-1 beta- and forskolin-induced synthesis and secretion of group II phospholipase A2 and prostaglandin E2 in rat mesangial cells is prevented by transforming growth factor-beta 2

1 reference

12 December 2020

Interleukin-1 beta-induced cytosolic phospholipase A2 activity and protein synthesis is blocked by dexamethasone in rat mesangial cells

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12 December 2020

Transforming growth factor-β2 inhibits interleukin 1β-induced expression of inducible nitric oxide synthase in rat renal mesangial cells

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12 December 2020

FTY720: a novel transplantation drug that modulates lymphocyte traffic rather than activation

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12 December 2020

Regulation of the expression of group IIA and group V secretory phospholipases A(2) in rat mesangial cells

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12 December 2020

Transforming growth factor-beta1: its anti-inflammatory and pro-fibrotic effects

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12 December 2020

Endogenous suppression of neutral-active and calcium-dependent phospholipase A2 in human polymorphonuclear leukocytes

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12 December 2020

Transforming growth factor β2 inhibits interleukin 1β- and tumour necrosis factor α-induction of nitric oxide synthase in rat renal mesangial cells

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12 December 2020

Identifiers

DOI

10.1038/SJ.BJP.0707171

1 reference

11 August 2017

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11 August 2017

PubMed publication ID

17325654

1 reference