Dendritic cell functional improvement in a preclinical model of lentiviral-mediated gene therapy for Wiskott-Aldrich syndrome (Q36043410)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22189416 AND SRC:MED&resulttype=core&format=json

19 January 2020

title

Dendritic cell functional improvement in a preclinical model of lentiviral-mediated gene therapy for Wiskott-Aldrich syndrome (English)

1 reference

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19 January 2020

main subject

gene therapy

0 references

Wiskott-Aldrich syndrome

1 reference

1 reference

1

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19 January 2020

Maria Carmina Castiello

4

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19 January 2020

Maria Grazia Roncarolo

7

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19 January 2020

Alessandro Aiuti

8

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19 January 2020

Federica Benvenuti

9

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19 January 2020

Anna Villa

10

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19 January 2020

author name string

F Prete

2

1 reference

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19 January 2020

M Bosticardo

3

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19 January 2020

E Draghici

5

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19 January 2020

M Locci

6

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19 January 2020

publication date

22 December 2011

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19 January 2020

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19 January 2020

volume

19

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19 January 2020

issue

12

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19 January 2020

page(s)

1150-1158

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Stem-cell gene therapy for the Wiskott-Aldrich syndrome

19 January 2020

cites work

1 reference

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2 October 2017

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Wiskott-Aldrich syndrome protein is required for homeostasis and function of invariant NKT cells

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2 October 2017

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Wiskott-Aldrich syndrome protein deficiency in B cells results in impaired peripheral homeostasis

2 October 2017

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Improvement of migratory defects in a murine model of Wiskott-Aldrich syndrome gene therapy

2 October 2017

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The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells

2 October 2017

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Wiskott-Aldrich syndrome protein is a key regulator of the phagocytic cup formation in macrophages

2 October 2017

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Impaired in vitro regulatory T cell function associated with Wiskott-Aldrich syndrome

2 October 2017

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The Wiskott-Aldrich syndrome protein is required for the function of CD4( )CD25( )Foxp3( ) regulatory T cells

2 October 2017

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Wiskott-Aldrich syndrome protein is required for regulatory T cell homeostasis

2 October 2017

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Defective Th1 cytokine gene transcription in CD4 and CD8 T cells from Wiskott-Aldrich syndrome patients.

2 October 2017

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Lentiviral vectors targeting WASp expression to hematopoietic cells, efficiently transduce and correct cells from WAS patients.

2 October 2017

1 reference

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Impaired integrin-dependent function in Wiskott-Aldrich syndrome protein-deficient murine and human neutrophils

2 October 2017

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2 October 2017

The leukocyte podosome

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2 October 2017

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Close encounters of different kinds: dendritic cells and NK cells take centre stage

2 October 2017

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Lentiviral vector-mediated gene transfer in T cells from Wiskott-Aldrich syndrome patients leads to functional correction.

2 October 2017

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Wiskott-Aldrich syndrome protein and the cytoskeletal dynamics of dendritic cells

2 October 2017

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In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccination

2 October 2017

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2 October 2017

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Wiskott-Aldrich syndrome protein is required for NK cell cytotoxicity and colocalizes with actin to NK cell-activating immunologic synapses

2 October 2017

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Configuration of human dendritic cell cytoskeleton by Rho GTPases, the WAS protein, and differentiation

2 October 2017

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Cutting edge: the Wiskott-Aldrich syndrome protein is required for efficient phagocytosis of apoptotic cells

2 October 2017

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Antigen receptor-induced activation and cytoskeletal rearrangement are impaired in Wiskott-Aldrich syndrome protein-deficient lymphocytes

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Impaired dendritic-cell homing in vivo in the absence of Wiskott-Aldrich syndrome protein

11 July 2018

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Mammalian cell expression of dimeric small immune proteins (SIP)

11 July 2018

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Results and long-term outcome in 39 patients with Wiskott-Aldrich syndrome transplanted from HLA-matched and -mismatched donors

11 July 2018

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Expression of Wiskott-Aldrich syndrome protein in dendritic cells regulates synapse formation and activation of naive CD8 T cells

23 September 2018

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Selection of an antibody library identifies a pathway to induce immunity by targeting CD36 on steady-state CD8 alpha dendritic cells.

23 September 2018

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WASP regulates suppressor activity of human and murine CD4( )CD25( )FOXP3( ) natural regulatory T cells

23 September 2018

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Efficacy of gene therapy for Wiskott-Aldrich syndrome using a WAS promoter/cDNA-containing lentiviral vector and nonlethal irradiation.

23 September 2018

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A lentiviral vector encoding the human Wiskott-Aldrich syndrome protein corrects immune and cytoskeletal defects in WASP knockout mice.

23 September 2018

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Efficient antigen presentation of soluble, but not particulate, antigen in the absence of Wiskott-Aldrich syndrome protein.

23 September 2018

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Gene therapy for Wiskott-Aldrich syndrome: rescue of T-cell signaling and amelioration of colitis upon transplantation of retrovirally transduced hematopoietic stem cells in mice

23 September 2018

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Wiskott-Aldrich syndrome protein regulates lipid raft dynamics during immunological synapse formation.

23 September 2018

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Wiskott-Aldrich syndrome protein deficiency leads to reduced B-cell adhesion, migration, and homing, and a delayed humoral immune response

23 September 2018

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Long-term survival and transplantation of haemopoietic stem cells for immunodeficiencies: report of the European experience 1968–99

21 January 2018

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Long-term outcome following hematopoietic stem-cell transplantation in Wiskott-Aldrich syndrome: collaborative study of the European Society for Immunodeficiencies and European Group for Blood and Marrow Transplantation

21 January 2018

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Intrinsic dendritic cell abnormalities in Wiskott-Aldrich syndrome

21 January 2018

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12 December 2020

Defective nuclear translocation of nuclear factor of activated T cells and extracellular signal-regulated kinase underlies deficient IL-2 gene expression in Wiskott-Aldrich syndrome

1 reference

12 December 2020

Outcome in patients with Wiskott-Aldrich syndrome following stem cell transplantation: an analysis of 57 patients in Japan

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12 December 2020

Stem cell transplantation for the Wiskott-Aldrich syndrome: a single-center experience confirms efficacy of matched unrelated donor transplantation

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12 December 2020

Impaired T-cell priming in vivo resulting from dysfunction of WASp-deficient dendritic cells

1 reference

12 December 2020

Cytoskeletal remodeling mediated by WASp in dendritic cells is necessary for normal immune synapse formation and T-cell priming

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12 December 2020

Wiskott-Aldrich syndrome protein is necessary for efficient IgG-mediated phagocytosis

1 reference

12 December 2020

Impact of donor type on outcome of bone marrow transplantation for Wiskott-Aldrich syndrome: collaborative study of the International Bone Marrow Transplant Registry and the National Marrow Donor Program

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12 December 2020

Identifiers

DOI

10.1038/GT.2011.202

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22189416 AND SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22189416 AND SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

22189416

1 reference