Mechanism and control of V(D)J recombination versus class switch recombination: similarities and differences (Q36037736)

11 August 2017

1 reference

title

Mechanism and control of V(D)J recombination versus class switch recombination: similarities and differences (English)

1 reference

11 August 2017

Darryll D Dudley

1

1 reference

11 August 2017

Jayanta Chaudhuri

series ordinal

2

1 reference

11 August 2017

Craig H Bassing

series ordinal

3

1 reference

11 August 2017

Frederick W Alt

series ordinal

4

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11 August 2017

publication date

1 January 2005

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11 August 2017

published in

Advances in Immunology

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11 August 2017

volume

86

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11 August 2017

page(s)

43-112

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Histone acetylation determines the developmentally regulated accessibility for T cell receptor gamma gene recombination

11 August 2017

cites work

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7 January 2021

RAG1 and RAG2 form a stable postcleavage synaptic complex with DNA containing signal ends in V(D)J recombination

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7 January 2021

Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system

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7 January 2021

Definition of minimal domains of interaction within the recombination-activating genes 1 and 2 recombinase complex

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7 January 2021

Distinct roles of RAG1 and RAG2 in binding the V(D)J recombination signal sequences

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7 January 2021

Deletion of the RAG2 C terminus leads to impaired lymphoid development in mice

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7 January 2021

Coordination of immunoglobulin DJH transcription and D-to-JH rearrangement by promoter-enhancer approximation

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7 January 2021

CD40 Ligand Gene Defects Responsible for X-Linked Hyper-IgM Syndrome

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7 January 2021

Activity of multiple light chain genes in murine myeloma cells producing a single, functional light chain

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7 January 2021

Immunoglobulin heavy-chain expression and class switching in a murine leukaemia cell line

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7 January 2021

Joining of immunoglobulin heavy chain gene segments: implications from a chromosome with evidence of three D-JH fusions

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7 January 2021

Phosphorylation and rapid relocalization of 53BP1 to nuclear foci upon DNA damage

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7 January 2021

Requirement of the activation-induced deaminase (AID) gene for immunoglobulin gene conversion

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7 January 2021

Identification of two topologically independent domains in RAG1 and their role in macromolecular interactions relevant to V(D)J recombination

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7 January 2021

The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome

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7 January 2021

Increased transcription levels induce higher mutation rates in a hypermutating cell line

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https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

A RAG1 and RAG2 tetramer complex is active in cleavage in V(D)J recombination

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https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements

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7 January 2021

Atm-deficient mice: a paradigm of ataxia telangiectasia

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7 January 2021

Early death and severe lymphopenia caused by ubiquitous expression of the Rag1 and Rag2 genes in mice

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https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

C-terminal deletion of AID uncouples class switch recombination from somatic hypermutation and gene conversion.

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https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Recombination signal sequences restrict chromosomal V(D)J recombination beyond the 12/23 rule.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX

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https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The mechanism and regulation of chromosomal V(D)J recombination

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https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Histone H2AX: a dosage-dependent suppressor of oncogenic translocations and tumors

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

T cell receptor (TCR) alpha/delta locus enhancer identity and position are critical for the assembly of TCR delta and alpha variable region genes.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Uracil DNA glycosylase activity is dispensable for immunoglobulin class switch

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

De novo protein synthesis is required for activation-induced cytidine deaminase-dependent DNA cleavage in immunoglobulin class switch recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Large-scale chromatin structure and function.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The protein Id: a negative regulator of helix-loop-helix DNA binding proteins

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Id: a negative regulator of helix-loop-helix DNA binding proteins. Control of terminal myogenic differentiation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The human immunoglobulin pseudo-gamma IGHGP gene shows no major structural defect

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Histone modifications in transcriptional regulation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Immunoglobulin kappa light chain gene rearrangement is impaired in mice deficient for DNA polymerase mu

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Hairpin coding end opening is mediated by RAG1 and RAG2 proteins

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Cytidine deaminase. The 2.3 A crystal structure of an enzyme: transition-state analog complex

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Replication protein A phosphorylation and the cellular response to DNA damage

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Analysis of variable (diversity) joining recombination in DNAdependent protein kinase (DNA-PK)-deficient mice reveals DNA-PK-independent pathways for both signal and coding joint formation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Exclusion and inclusion of α and β T cell receptor alleles

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Gene-targeted deletion and replacement mutations of the T-cell receptor beta-chain enhancer: the role of enhancer elements in controlling V(D)J recombination accessibility.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Rearrangement of T-cell receptor beta-chain genes during T-cell development

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

DNA-dependent protein kinase activity is not required for immunoglobulin class switching

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Deletion of the IgH intronic enhancer and associated matrix-attachment regions decreases, but does not abolish, class switching at the mu locus

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Deletion of the mouse T-cell receptor beta gene enhancer blocks alphabeta T-cell development

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

DNA Double-Strand Breaks in Immunoglobulin Genes Undergoing Somatic Hypermutation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

DNA double-strand breaks: prior to but not sufficient in targeting hypermutation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Mammalian DNA mismatch repair

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

ATM phosphorylates histone H2AX in response to DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

DNA looping by Ku and the DNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

T cell receptor genes in a series of class I major histocompatibility complex-restricted cytotoxic T lymphocyte clones specific for a Plasmodium berghei nonapeptide: implications for T cell allelic exclusion and antigen-specific repertoire

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Ku80 is required for immunoglobulin isotype switching

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

OcaB is required for normal transcription and V(D)J recombination of a subset of immunoglobulin kappa genes

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The block in immunoglobulin class switch recombination caused by activation-induced cytidine deaminase deficiency occurs prior to the generation of DNA double strand breaks in switch mu region

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Genomic instability in mice lacking histone H2AX

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Apobec-1 and apolipoprotein B mRNA editing

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Class-switch recombination: interplay of transcription, DNA deamination and DNA repair

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Transcription-targeted DNA deamination by the AID antibody diversification enzyme

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Replication protein A interacts with AID to promote deamination of somatic hypermutation targets

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Response to RAG-mediated VDJ cleavage by NBS1 and gamma-H2AX

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Mutations of the intronic IgH enhancer and its flanking sequences differentially affect accessibility of the JH locus.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Variable deletion and duplication at recombination junction ends: implication for staggered double-strand cleavage in class-switch recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

V(D)J recombination is not activated by demethylation of the kappa locus

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The function of AID in somatic mutation and class switch recombination: upstream or downstream of DNA breaks

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The recombination activating gene-1 (RAG-1) transcript is present in the murine central nervous system

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

A class switch control region at the 3′ end of the immunoglobulin heavy chain locus

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Reduced switching in SCID B cells is associated with altered somatic mutation of recombined S regions

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Collaboration of homologous recombination and nonhomologous end-joining factors for the survival and integrity of mice and cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

DNA end-joining: from yeast to man

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Nonhomologous end joining and V(D)J recombination require an additional factor

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

T-cell antigen receptor genes and T-cell recognition

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

An immunoglobulin heavy-chain gene is formed by at least two recombinational events

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Surface expression of two distinct functional antigen receptors on human gamma delta T cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Synapsis of DNA ends by DNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

G4 DNA binding by LR1 and its subunits, nucleolin and hnRNP D, A role for G-G pairing in immunoglobulin switch recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

HeLa nuclear protein recognizing DNA termini and translocating on DNA forming a regular DNA-multimeric protein complex

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

AID mediates hypermutation by deaminating single stranded DNA.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

RAG1 mediates signal sequence recognition and recruitment of RAG2 in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

CD40 ligand mutations in X-linked immunodeficiency with hyper-IgM

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-kappaB signaling

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

De novo protein synthesis is required for the activation-induced cytidine deaminase function in class-switch recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

A role for Saccharomyces cerevisiae histone H2A in DNA repair.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Internal IgH class switch region deletions are position-independent and enhanced by AID expression

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Impaired V(D)J recombination and lymphocyte development in core RAG1-expressing mice.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

DNA sequences at immunoglobulin switch region recombination sites

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Terminal defects of B lymphocyte differentiation.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Human genetic defects in class-switch recombination (hyper-IgM syndromes).

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Initiation of V(D)J recombination in vitro obeying the 12/23 rule

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Deficiency in Msh2 affects the efficiency and local sequence specificity of immunoglobulin class-switch recombination: parallels with somatic hypermutation.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Switch junction sequences in PMS2-deficient mice reveal a microhomology-mediated mechanism of Ig class switch recombination.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The C-terminal portion of RAG2 protects against transposition in vitro

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

XR-C1, a new CHO cell mutant which is defective in DNA-PKcs, is impaired in both V(D)J coding and signal joint formation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

RNA-editing cytidine deaminase Apobec-1 is unable to induce somatic hypermutation in mammalian cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Disruption of the lineage restriction of TCR beta gene rearrangements.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Early alpha beta T cell development in the thymus of normal and genetically altered mice

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Mutations of CD40 gene cause an autosomal recessive form of immunodeficiency with hyper IgM.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Transcription of germ line V alpha segments correlates with ongoing T-cell receptor alpha-chain rearrangement

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. II. Prolonged suppression of the humoral immune response by an antibody to the ligand for CD40, gp39

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

gp39-CD40 interactions are essential for germinal center formation and the development of B cell memory

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Induction of the transcription factors NF-kappa B, AP-1 and NF-AT during B cell stimulation through the CD40 receptor

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Identification of basic residues in RAG2 critical for DNA binding by the RAG1-RAG2 complex

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The RAG proteins and V(D)J recombination: complexes, ends, and transposition

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Identification of two catalytic residues in RAG1 that define a single active site within the RAG1/RAG2 protein complex.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Non-redundancy of cytidine deaminases in class switch recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Isolation of an excision product of T-cell receptor alpha-chain gene rearrangements

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Evidence for a CD40 response element, distinct from the IL-4 response element, in the germline epsilon promoter

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Somatic hypermutation in the heavy chain locus correlates with transcription

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Murine cell line SX9 bearing a mutation in the dna-pkcs gene exhibits aberrant V(D)J recombination not only in the coding joint but also in the signal joint

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Signal joint formation is also impaired in DNA-dependent protein kinase catalytic subunit knockout cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

ATM-dependent phosphorylation of nibrin in response to radiation exposure

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Receptor editing: an approach by autoreactive B cells to escape tolerance

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

DNA replication and chromatin.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Mice lacking TdT: mature animals with an immature lymphocyte repertoire

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Comparative genomics of the human and mouse T cell receptor loci

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Nucleosome structure completely inhibits in vitro cleavage by the V(D)J recombinase

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Ordered rearrangement of variable region genes of the T cell receptor gamma locus correlates with transcription of the unrearranged genes.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The balance between Pax5 and Id2 activities is the key to AID gene expression

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The Ig(kappa) enhancer influences the ratio of Ig(kappa) versus Ig(lambda) B lymphocytes

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

CD40-mediated regulation of immune responses by TRAF-dependent and TRAF-independent signaling mechanisms.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Down-regulation of RAG1 and RAG2 gene expression in PreB cells after functional immunoglobulin heavy chain rearrangement

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Expression of activation-induced cytidine deaminase in human B-cell non-Hodgkin lymphomas

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Somatic mutation and the maturation of immune response to 2-phenyl oxazolone

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

High affinity cooperative DNA binding by the yeast Mlh1-Pms1 heterodimer

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Neoteny in lymphocytes: Rag1 and Rag2 expression in germinal center B cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Expression of activation-induced cytidine deaminase (AID) in Burkitt lymphoma cells: rare AID-negative cell lines with the unmutated rearranged VH gene

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Activation-induced cytidine deaminase expression in follicular lymphoma: association between AID expression and ongoing mutation in FL.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Integrating DNA: transposases and retroviral integrases

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Somatic hypermutation and the three R's: repair, replication and recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

RNA editing enzyme APOBEC1 and some of its homologs can act as DNA mutators

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Processing of switch transcripts is required for targeting of antibody class switch recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Accessibility control of V(D)J recombination: lessons from gene targeting

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Extrachromosomal DNA substrates in pre-B cells undergo inversion or deletion at immunoglobulin V-(D)-J joining signals

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

V(D)J recombination: a functional definition of the joining signals

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Factors and forces controlling V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Reexpression of RAG-1 and RAG-2 genes in activated mature mouse B cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

A stable RAG1-RAG2-DNA complex that is active in V(D)J cleavage

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Assembly of a 12/23 paired signal complex: a critical control point in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

DNA transposition by the RAG1 and RAG2 proteins: a possible source of oncogenic translocations

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Genome maintenance mechanisms for preventing cancer

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Organization of immunoglobulin heavy chain genes and allelic deletion model

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Molecular mechanism of class switch recombination: linkage with somatic hypermutation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

A conserved transcriptional enhancer regulates RAG gene expression in developing B cells.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Transcription from the RAG1 locus marks the earliest lymphocyte progenitors in bone marrow

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Hyper-IgM syndrome type 4 with a B lymphocyte-intrinsic selective deficiency in Ig class-switch recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Essential roles of the kappa light chain intronic enhancer and 3' enhancer in kappa rearrangement and demethylation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Circular DNA is excised by immunoglobulin class switch recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Sensing and repairing DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Towards an understanding of somatic hypermutation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Specific missense mutations in NEMO result in hyper-IgM syndrome with hypohydrotic ectodermal dysplasia

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Translating the Histone Code

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Intermediates in V(D)J recombination: a stable RAG1/2 complex sequesters cleaved RSS ends.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Ordered assembly of the V(D)J synaptic complex ensures accurate recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Unraveling V(D)J recombination; insights into gene regulation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Extrachromosomal recombination substrates recapitulate beyond 12/23 restricted VDJ recombination in nonlymphoid cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Shutdown of class switch recombination by deletion of a switch region control element.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Gene Selection in Hemoglobin and in Antibody-Synthesizing Cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Rearrangement of immunoglobulin gamma 1-chain gene and mechanism for heavy-chain class switch

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Repetitive sequences in class-switch recombination regions of immunoglobulin heavy chain genes

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The coupling between enhancer activity and hypomethylation of kappa immunoglobulin genes is developmentally regulated

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Class-switch recombination: after the dawn of AID.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Immunoglobulin class-switch recombination in mice devoid of any S mu tandem repeat.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

DNA double-strand breaks: signaling, repair and the cancer connection

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

T cell receptor gamma and delta gene junctional sequences in SCID mice: excessive P nucleotide insertion

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Mutations of acidic residues in RAG1 define the active site of the V(D)J recombinase

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Regions of RAG1 protein critical for V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Dual role of RAG2 in V(D)J recombination: catalysis and regulation of ordered Ig gene assembly

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Lack of N regions in antigen receptor variable region genes of TdT-deficient lymphocytes

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Gene segment selection in V(D)J recombination: accessibility and beyond

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

DNA glycosylases in the base excision repair of DNA

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Normal isotype switching in B cells lacking the I mu exon splice donor site: evidence for multiple I mu-like germline transcripts.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Accessibility of nucleosomal DNA to V(D)J cleavage is modulated by RSS positioning and HMG1.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Junctional sequences of T cell receptor gamma delta genes: implications for gamma delta T cell lineages and for a novel intermediate of V-(D)-J joining.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

T cell-dependent induction of NF-kappa B in B cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Mutational analysis of RAG1 and RAG2 identifies three catalytic amino acids in RAG1 critical for both cleavage steps of V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Ig heavy chain class switching in Rag-deficient mice

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Distinct factors regulate the murine RAG-2 promoter in B- and T-cell lines

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Frequent but biased class switch recombination in the S mu flanking regions.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

RAG proteins shepherd double-strand breaks to a specific pathway, suppressing error-prone repair, but RAG nicking initiates homologous recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

rag-1 and rag-2 are components of a high-molecular-weight complex, and association of rag-2 with this complex is rag-1 dependent

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Coding Joint Formation in a Cell-Free V(D)J Recombination System

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

DNA elements are asymmetrically joined during the site-specific recombination of kappa immunoglobulin genes

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Continuing kappa-gene rearrangement in a cell line transformed by Abelson murine leukemia virus

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The mechanism of V(D)J joining: lessons from molecular, immunological, and comparative analyses

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

P nucleotide insertions and the resolution of hairpin DNA structures in mammalian cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The origins of V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Novel strand exchanges in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The "dispensable" portion of RAG2 is necessary for efficient V-to-DJ rearrangement during B and T cell development

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Variegated transcriptional activation of the immunoglobulin kappa locus in pre-b cells contributes to the allelic exclusion of light-chain expression

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Site‐specific recombination in the immune system 1

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The defect in murine severe combined immune deficiency: joining of signal sequences but not coding segments in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Tying loose ends: roles of Ku and DNA-dependent protein kinase in the repair of double-strand breaks

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Activation of NF-kappaB/Rel by CD40 engagement induces the mouse germ line immunoglobulin Cgamma1 promoter

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The ability of CD40L, but not lipopolysaccharide, to initiate immunoglobulin switching to immunoglobulin G1 is explained by differential induction of NF-kappaB/Rel proteins

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Regulation of V(D)J recombination activator protein RAG-2 by phosphorylation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

V(D)J recombination and the cell cycle.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Suppression of spontaneous mutagenesis in human cells by DNA base excision-repair

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Switch transcripts in immunoglobulin class switching

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The mu switch region tandem repeats are important, but not required, for antibody class switch recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Structure and expression of germ line immunoglobulin gamma 2b transcripts

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

IgA production without mu or delta chain expression in developing B cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Identification of a locus control region in the immunoglobulin heavy-chain locus that deregulates c-myc expression in plasmacytoma and Burkitt's lymphoma cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Direct evidence for chromosomal inversion during T-cell receptor beta-gene rearrangements

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

A T cell clone expresses two T cell receptor alpha genes but uses one alpha beta heterodimer for allorecognition and self MHC-restricted antigen recognition

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Regulation of TCR alpha and beta gene allelic exclusion during T-cell development

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The scid defect affects the final step of the immunoglobulin VDJ recombinase mechanism

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Novel antibody switching defects in human patients

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Ku70 is required for late B cell development and immunoglobulin heavy chain class switching

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Class switching in B cells lacking 3' immunoglobulin heavy chain enhancers.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

IgH class switch recombination to IgG1 in DNA-PKcs-deficient B cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Mechanism and control of class-switch recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Elucidation of a downstream boundary of the 3' IgH regulatory region

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

H2A.X. a histone isoprotein with a conserved C-terminal sequence, is encoded by a novel mRNA with both DNA replication type and polyA 3' processing signals

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Marginal-zone B cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Somatic hypermutation of the AID transgene in B and non-B cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

hMre11 and hRad50 Nuclear Foci Are Induced During the Normal Cellular Response to DNA Double-Strand Breaks †

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Transcriptional regulation of immunoglobulin V genes

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Methylation status and DNase I sensitivity of immunoglobulin genes: changes associated with rearrangement

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Chromatin remodeling by the T cell receptor (TCR)-beta gene enhancer during early T cell development: Implications for the control of TCR-beta locus recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Replication protein A confers structure-specific endonuclease activities to the XPF-ERCC1 and XPG subunits of human DNA repair excision nuclease

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Sequences of five potential recombination sites encoded close to an immunoglobulin kappa constant region gene

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Stimulation of V(D)J recombination by histone acetylation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Somatic hypermutation is limited by CRM1-dependent nuclear export of activation-induced deaminase

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The surrogate light chain in B-cell development.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The roles of preB and B cell receptors in the stepwise allelic exclusion of mouse IgH and L chain gene loci

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

In vivo transposition mediated by V(D)J recombinase in human T lymphocytes

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The role of DNA breaks in genomic instability and tumorigenesis

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Rad54 and DNA Ligase IV cooperate to maintain mammalian chromatid stability

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

RAG2 is down-regulated by cytoplasmic sequestration and ubiquitin-dependent degradation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Molecular visualization of immunoglobulin switch region RNA/DNA complex by atomic force microscope

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

RAG-1-deficient mice have no mature B and T lymphocytes

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

RAG2 is regulated differentially in B and T cells by elements 5' of the promoter

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

RAG2:GFP Knockin Mice Reveal Novel Aspects of RAG2 Expression in Primary and Peripheral Lymphoid Tissues

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Developmental regulation of TCR delta locus accessibility and expression by the TCR delta enhancer.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Antigen receptor loci poised for V(D)J rearrangement are broadly associated with BRG1 and flanked by peaks of histone H3 dimethylated at lysine 4

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Unusual immunoglobulin gene rearrangement leads to replacement of recombinational signal sequences

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Receptor revision in T cells: an open question?

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Kappa chain monoallelic demethylation and the establishment of allelic exclusion

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Chromatin dynamics and locus accessibility in the immune system

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The lingering enigma of the allelic exclusion mechanism

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Assembly of the RAG1/RAG2 synaptic complex

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Microsites for immunoglobulin switch recombination breakpoints from Xenopus to mammals

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Sequence of the spacer in the recombination signal sequence affects V(D)J rearrangement frequency and correlates with nonrandom Vkappa usage in vivo

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Regulation of RAG expression in developing lymphocytes

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Activation-induced deaminase (AID)-directed hypermutation in the immunoglobulin Smu region: implication of AID involvement in a common step of class switch recombination and somatic hypermutation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Transcription-coupled events associating with immunoglobulin switch region chromatin

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

In situ visualization of DNA double-strand break repair in human fibroblasts

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Revising B cell receptors

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Immunity through DNA deamination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Lysine-79 of histone H3 is hypomethylated at silenced loci in yeast and mammalian cells: a potential mechanism for position-effect variegation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

A human severe combined immunodeficiency (SCID) condition with increased sensitivity to ionizing radiations and impaired V(D)J rearrangements defines a new DNA recombination/repair deficiency

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Radiosensitive SCID patients with Artemis gene mutations show a complete B-cell differentiation arrest at the pre-B-cell receptor checkpoint in bone marrow.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

1 reference

7 January 2021

Requirement for Ku80 in growth and immunoglobulin V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Immune receptor editing: revise and select

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

How to keep V(D)J recombination under control

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Constitutive expression of AID leads to tumorigenesis

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The AID enzyme induces class switch recombination in fibroblasts

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

T cell receptor beta gene sequences in the circular DNA of thymocyte nuclei: direct evidence for intramolecular DNA deletion in V-D-J joining

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Targeted inhibition of V(D)J recombination by a histone methyltransferase

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Expression of two T cell receptor alpha chains: dual receptor T cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Alternative end joining during switch recombination in patients with ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

ATM is not required in somatic hypermutation of VH, but is involved in the introduction of mutations in the switch mu region

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

V(D)J Recombination in Mature B Cells: A Mechanism for Altering Antibody Responses

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Cell-cycle-regulated DNA double-stranded breaks in somatic hypermutation of immunoglobulin genes

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The activation-induced deaminase functions in a postcleavage step of the somatic hypermutation process

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

A mechanistic basis for Mre11-directed DNA joining at microhomologies

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The central domain of core RAG1 preferentially recognizes single-stranded recombination signal sequence heptamer

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Sensing of intermediates in V(D)J recombination by ATM.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Somatic hypermutation of immunoglobulin genes is linked to transcription initiation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

In Vitro Deamination of Cytosine to Uracil in Single-stranded DNA by Apolipoprotein B Editing Complex Catalytic Subunit 1 (APOBEC1)

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

T cell receptor gene recombination patterns and mechanisms: cell death, rescue, and T cell production

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Localization of the 3' IgH locus elements that effect long-distance regulation of class switch recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Molecular and biochemical characterisation of DNA-dependent protein kinase-defective rodent mutant irs-20

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Separation-of-function mutants reveal critical roles for RAG2 in both the cleavage and joining steps of V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

E2A activity is induced during B-cell activation to promote immunoglobulin class switch recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

E protein function in lymphocyte development

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

AID-GFP chimeric protein increases hypermutation of Ig genes with no evidence of nuclear localization

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

B lymphocytes may escape tolerance by revising their antigen receptors

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

A non-B-DNA structure at the Bcl-2 major breakpoint region is cleaved by the RAG complex

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

AID is required for c-myc/IgH chromosome translocations in vivo

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Ku protein stimulates DNA end joining by mammalian DNA ligases: a direct role for Ku in repair of DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Cell-free V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Developmental regulation of T-cell receptor gene expression

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

DNA Methylation and Gene Function

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Induction of RNA-stabilized DMA conformers by transcription of an immunoglobulin switch region

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

ATM is required for efficient recombination between immunoglobulin switch regions

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

What role for AID: mutator, or assembler of the immunoglobulin mutasome?

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Epigenetic codes for heterochromatin formation and silencing: rounding up the usual suspects

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The expression pattern of Id4, a novel dominant negative helix-loop-helix protein, is distinct from Id1, Id2 and Id3

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Id helix-loop-helix proteins antagonize pax transcription factor activity by inhibiting DNA binding

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

A dimer of the lymphoid protein RAG1 recognizes the recombination signal sequence and the complex stably incorporates the high mobility group protein HMG2.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

DNA Double-stranded Breaks Induce Histone H2AX Phosphorylation on Serine 139

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Megabase chromatin domains involved in DNA double-strand breaks in vivo

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Selection events operating at various stages in B cell development

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Genetic evidence that the RAG1 protein directly participates in V(D)J recombination through substrate recognition

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Complementation of V(D)J Recombination Deficiency in RAG-1−/− B Cells Reveals a Requirement for Novel Elements in the N-Terminus of RAG-1

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Leaky Scid phenotype associated with defective V(D)J coding end processing in Artemis-deficient mice

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Defective DNA repair and increased genomic instability in Artemis-deficient murine cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The role of the non-homologous end-joining pathway in lymphocyte development

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Restraining the V(D)J recombinase

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

V(D)J recombination: broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Expression and V(D)J recombination activity of mutated RAG-1 proteins

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Definition of a core region of RAG-2 that is functional in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Analysis and expression of a cloned pre-T cell receptor gene

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The Ig heavy chain intronic enhancer core region is necessary and sufficient to promote efficient class switch recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Sequences at the somatic recombination sites of immunoglobulin light-chain genes

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Identification and nucleotide sequence of a diversity DNA segment (D) of immunoglobulin heavy-chain genes

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

V(D)J recombination: modulation of RAG1 and RAG2 cleavage activity on 12/23 substrates by whole cell extract and DNA-bending proteins

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

E-proteins directly regulate expression of activation-induced deaminase in mature B cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Characteristics of the immunoglobulin Vkappa genes, pseudogenes, relics and orphons in the mouse genome

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Stable expression of immunoglobulin gene V(D)J recombinase activity by gene transfer into 3T3 fibroblasts

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The V(D)J recombination activating gene, RAG-1.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Activation of immunoglobulin kappa gene rearrangement correlates with induction of germline kappa gene transcription

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Mlh1 Can Function in Antibody Class Switch Recombination Independently of Msh2

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Coding joint formation of endogenous T cell receptor genes in lymphoid cells from scid mice: unusual P-nucleotide additions in VJ-coding joints

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

RAG mutations in human B cell-negative SCID.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

An expressed neo(r) cassette provides required functions of the 1gamma2b exon for class switching.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Position-dependent inhibition of class-switch recombination by PGK-neor cassettes inserted into the immunoglobulin heavy chain constant region locus

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Increased accumulation of hybrid V(D)J joins in cells expressing truncated versus full-length RAGs.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Ataxia-telangiectasia and the Nijmegen breakage syndrome: related disorders but genes apart

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

ATM and ATR: networking cellular responses to DNA damage

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The influence of transcriptional orientation on endogenous switch region function

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Separate domains of AID are required for somatic hypermutation and class-switch recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

DNA hairpin opening mediated by the RAG1 and RAG2 proteins

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Accessibility control of antigen-receptor variable-region gene assembly: role of cis-acting elements

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Function of the TCR alpha enhancer in alphabeta and gammadelta T cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Assembly of productive T cell receptor delta variable region genes exhibits allelic inclusion

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Mechanisms that direct ordered assembly of T cell receptor beta locus V, D, and J gene segments

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The DNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Human activation-induced cytidine deaminase causes transcription-dependent, strand-biased C to U deaminations

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The homeodomain region of Rag-1 reveals the parallel mechanisms of bacterial and V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Promoter activation by enhancer-dependent and -independent loading of activator and coactivator complexes

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Cell type-specific chromatin structure determines the targeting of V(D)J recombinase activity in vitro

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Roles of the "dispensable" portions of RAG-1 and RAG-2 in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The language of covalent histone modifications

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The immunoglobulin heavy-chain enhancer functions as the promoter for I mu sterile transcription

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Multitasking of helix-loop-helix proteins in lymphopoiesis

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Id proteins Id1 and Id2 selectively inhibit DNA binding by one class of helix-loop-helix proteins

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Fine structure and activity of discrete RAG-HMG complexes on V(D)J recombination signals

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

A RAG-1/RAG-2 tetramer supports 12/23-regulated synapsis, cleavage, and transposition of V(D)J recombination signals

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

RAG-2 promotes heptamer occupancy by RAG-1 in the assembly of a V(D)J initiation complex

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

AID mutant analyses indicate requirement for class-switch-specific cofactors

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Impairment of V(D)J recombination in double-strand break repair mutants

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Palindromic but not G-rich sequences are targets of class switch recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Distinct and opposite diversifying activities of terminal transferase splice variants

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

New insights into V(D)J recombination and its role in the evolution of the immune system

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Transcription-induced cleavage of immunoglobulin switch regions by nucleotide excision repair nucleases in vitro

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Receptor editing in self-reactive bone marrow B cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Cutting edge: targeting of V beta to D beta rearrangement by RSSs can be mediated by the V(D)J recombinase in the absence of additional lymphoid-specific factors

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Somatic generation of antibody diversity

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Somatic Changes in the Content and Context of Immunoglobulin Genes

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Regulation of RAG1/RAG2-mediated transposition by GTP and the C-terminal region of RAG2

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Evidence of a critical architectural function for the RAG proteins in end processing, protection, and joining in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Dividing the empire: boundary chromatin elements delimit the territory of enhancers

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Stimulation of V(D)J cleavage by high mobility group proteins

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Partial V(D)J recombination activity leads to Omenn syndrome

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Omenn syndrome: a disorder of Rag1 and Rag2 genes.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

V(D)J recombination defects in lymphocytes due to RAG mutations: severe immunodeficiency with a spectrum of clinical presentations

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Defect in rearrangement of the most 5' TCR-J alpha following targeted deletion of T early alpha (TEA): implications for TCR alpha locus accessibility.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Germ-line transcription and methylation status of the TCR-J alpha locus in its accessible configuration.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Pleiotropic changes controlled by the pre-T-cell receptor

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Characterization of immune function and analysis of RAG gene mutations in Omenn syndrome and related disorders

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Disorders of B cells and helper T cells in the pathogenesis of the immunoglobulin deficiency of patients with ataxia telangiectasia

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

53BP1 is required for class switch recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

A regulatory role for recombinase activating genes, RAG-1 and RAG-2, in T cell development

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Megabase inversions in the human genome as physiological events

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The RAG-HMG1 complex enforces the 12/23 rule of V(D)J recombination specifically at the double-hairpin formation step

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Productive and nonproductive complexes of Ku and DNA-dependent protein kinase at DNA termini

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Control of V(D)J recombinational accessibility of the D beta 1 gene segment at the TCR beta locus by a germline promoter

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Deletion of germline promoter PD beta 1 from the TCR beta locus causes hypermethylation that impairs D beta 1 recombination by multiple mechanisms.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Developmental regulation of V(D)J recombination and lymphocyte differentiation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Evolution of autoantibody responses via somatic hypermutation outside of germinal centers

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

LR1, a lipopolysaccharide-responsive factor with binding sites in the immunoglobulin switch regions and heavy-chain enhancer

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Directed Ig class switch recombination in activated murine B cells.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

REPLICATION PROTEIN A: A Heterotrimeric, Single-Stranded DNA-Binding Protein Required for Eukaryotic DNA Metabolism

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Induction of somatic hypermutation is associated with modifications in immunoglobulin variable region chromatin

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Dramatically increased rearrangement and peripheral representation of Vbeta14 driven by the 3'Dbeta1 recombination signal sequence.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Negative cell cycle regulation and DNA damage-inducible phosphorylation of the BRCT protein 53BP1.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Deletion of the Ig kappa light chain intronic enhancer/matrix attachment region impairs but does not abolish V kappa J kappa rearrangement

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Developmentally controlled and tissue-specific expression of unrearranged VH gene segments

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Regulation of the assembly and expression of variable-region genes

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

A cis element in the recombination activating gene locus regulates gene expression by counteracting a distant silencer

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Joining-deficient RAG1 mutants block V(D)J recombination in vivo and hairpin opening in vitro

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Id helix-loop-helix proteins inhibit nucleoprotein complex formation by the TCF ETS-domain transcription factors

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Influence of immunoglobulin heavy- and light-chain expression on B-cell differentiation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The nicking step in V(D)J recombination is independent of synapsis: implications for the immune repertoire

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

DNA substrate length and surrounding sequence affect the activation-induced deaminase activity at cytidine

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Coordinate regulation of RAG1 and RAG2 by cell type-specific DNA elements 5' of RAG2

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Continued RAG expression in late stages of B cell development and no apparent re-induction after immunizion

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The RAG1 N-terminal domain is an E3 ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The immunoglobulin kappa locus-or-what has been learned from looking closely at one-tenth of a percent of the human genome

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

An evolutionarily conserved target motif for immunoglobulin class-switch recombination

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Immunoglobulin gene hypermutation in germinal centers is independent of the RAG-1 V(D)J recombinase

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations.

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

The helix-loop-helix gene E2A is required for B cell formation

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Recombination and transcription of the endogenous Ig heavy chain locus is effected by the Ig heavy chain intronic enhancer core region in the absence of the matrix attachment regions

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

Regulation of immunoglobulin light chain isotype expression

1 reference

https://api.crossref.org/works/10.1016/S0065-2776(04)86002-4

7 January 2021

10.1016/S0065-2776(04)86002-4

Identifiers

DOI

1 reference

11 August 2017

1 reference