Development and characterization of a vaginal film containing dapivirine, a non-nucleoside reverse transcriptase inhibitor (NNRTI), for prevention of HIV-1 sexual transmission (Q36033871)

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scientific article published on June 1, 2011

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English	Development and characterization of a vaginal film containing dapivirine, a non-nucleoside reverse transcriptase inhibitor (NNRTI), for prevention of HIV-1 sexual transmission	scientific article published on June 1, 2011

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Development and Characterization of a Vaginal Film Containing Dapivirine, a Non- nucleoside Reverse Transcriptase Inhibitor (NNRTI), for prevention of HIV-1 sexual transmission (English)

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Development and characterization of a vaginal film containing dapivirine, a non-nucleoside reverse transcriptase inhibitor (NNRTI), for prevention of HIV-1 sexual transmission (English)

1 reference

10.1007/S13346-011-0022-6

https://api.crossref.org/works/10.1007/S13346-011-0022-6

4 January 2025

sexual transmission

0 references

HIV transmission

0 references

sexually transmitted infection

0 references

prevention of HIV/AIDS

0 references

author name string

Ayman Akil

1

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Mingguang Li

6

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Lisa Cencia Rohan

7

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Michael A. Parniak

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:22708075

4 January 2025

Charlene S. Dezzuitti

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:22708075

4 January 2025

Bernard J. Moncla

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:22708075

4 January 2025

Marilyn R. Cost

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:22708075

4 January 2025

language of work or name

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22708075

4 January 2025

publication date

1 June 2011

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

full work available at URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375737

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:22708075

4 January 2025

https://europepmc.org/articles/PMC3375737

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Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:22708075

4 January 2025

https://europepmc.org/articles/PMC3375737?pdf=render

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:22708075

4 January 2025

https://doi.org/10.1007/s13346-011-0022-6

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:22708075

4 January 2025

http://link.springer.com/content/pdf/10.1007/s13346-011-0022-6.pdf

1 reference

10.1007/S13346-011-0022-6

https://api.crossref.org/works/10.1007/S13346-011-0022-6

4 January 2025

http://link.springer.com/article/10.1007/s13346-011-0022-6/fulltext.html

HyperText Markup Language

1 reference

10.1007/S13346-011-0022-6

https://api.crossref.org/works/10.1007/S13346-011-0022-6

4 January 2025

http://link.springer.com/content/pdf/10.1007/s13346-011-0022-6

1 reference

10.1007/S13346-011-0022-6

https://api.crossref.org/works/10.1007/S13346-011-0022-6

4 January 2025

Drug delivery and translational research

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

1

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

3

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

209-222

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

In vitro and ex vivo testing of tenofovir shows it is effective as an HIV-1 microbicide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

The mutation T477A in HIV-1 reverse transcriptase (RT) restores normal proteolytic processing of RT in virus with Gag-Pol mutated in the p51-RNH cleavage site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

A novel itraconazole bioadhesive film for vaginal delivery: design, optimization, and physicodynamic characterization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

The future of HIV microbicides: challenges and opportunities.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Microbicide delivery: formulation technologies and strategies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Microbicides: chemistry, structure, and strategy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Vaginal drug delivery systems for HIV prevention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Characterization of cyclodextrin inclusion complexes of the anti-HIV non-nucleoside reverse transcriptase inhibitor UC781

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Inhibition of human immunodeficiency virus type 1 infection by the candidate microbicide dapivirine, a nonnucleoside reverse transcriptase inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Vaginal microbicides: where are we and where are we going?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Killing of Neisseria gonorrhoeae, Streptococcus agalactiae (group B streptococcus), Haemophilus ducreyi, and vaginal Lactobacillus by 3-O-octyl-sn-glycerol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Concentrations of dapivirine in the rhesus macaque and rabbit following once daily intravaginal administration of a gel formulation of [14C]dapivirine for 7 days.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Preclinical testing of candidate topical microbicides for anti-human immunodeficiency virus type 1 activity and tissue toxicity in a human cervical explant culture.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Microbicide drug candidates to prevent HIV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Dose-ranging phase 1 study of TMC120, a promising vaginal microbicide, in HIV-negative and HIV-positive female volunteers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

A dual chamber model of female cervical mucosa for the study of HIV transmission and for the evaluation of candidate HIV microbicides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

In vitro microbicidal activity of the nonnucleoside reverse transcriptase inhibitor (NNRTI) UC781 against NNRTI-resistant human immunodeficiency virus type 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Acceptability of five nonoxynol-9 spermicides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

In vitro and in vivo: the story of nonoxynol 9.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Development and characterization of bioadhesive vaginal films of sodium polystyrene sulfonate (PSS), a novel contraceptive antimicrobial agent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Water dispersible microbicidal cellulose acetate phthalate film

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Blocking of cell-free and cell-associated HIV-1 transmission through human cervix organ culture with UC781.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Attenuated infectivity of HIV type 1 from epithelial cells pretreated with a tight-binding nonnucleoside reverse transcriptase inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

A tight-binding mode of inhibition is essential for anti-human immunodeficiency virus type 1 virucidal activity of nonnucleoside reverse transcriptase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Acceptability research on female-controlled barrier methods to prevent heterosexual transmission of HIV: Where have we been? Where are we going?

1 reference

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2 October 2017

Acceptability of two spermicides in five countries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

A controlled trial of nonoxynol 9 film to reduce male-to-female transmission of sexually transmitted diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375737

2 October 2017

Vaginal microbicides: moving ahead after an unexpected setback

1 reference

https://api.crossref.org/works/10.1007/S13346-011-0022-6

21 January 2018

Sustained release of microbicides by newly engineered vaginal rings

1 reference

https://api.crossref.org/works/10.1007/S13346-011-0022-6

21 January 2018

Polyurethane intravaginal ring for controlled delivery of dapivirine, a nonnucleoside reverse transcriptase inhibitor of HIV-1.

1 reference

https://api.crossref.org/works/10.1007/S13346-011-0022-6

21 January 2018

Intravaginal ring delivery of the reverse transcriptase inhibitor TMC 120 as an HIV microbicide

1 reference

https://api.crossref.org/works/10.1007/S13346-011-0022-6

21 January 2018

Long-term, controlled release of the HIV microbicide TMC120 from silicone elastomer vaginal rings.

1 reference

https://api.crossref.org/works/10.1007/S13346-011-0022-6

21 January 2018

Safety, tolerability, and systemic absorption of dapivirine vaginal microbicide gel in healthy, HIV-negative women

1 reference

https://api.crossref.org/works/10.1007/S13346-011-0022-6

21 January 2018

Pharmacokinetics of 2 dapivirine vaginal microbicide gels and their safety vs. Hydroxyethyl cellulose-based universal placebo gel.

1 reference

https://api.crossref.org/works/10.1007/S13346-011-0022-6

21 January 2018

Design and in vitro evaluation of a novel bioadhesive vaginal drug delivery system for clindamycin phosphate

1 reference

https://api.crossref.org/works/10.1007/S13346-011-0022-6

21 January 2018

Why nonoxynol-9 may have failed to prevent acquisition of Neisseria gonorrhoeae in clinical trials

1 reference

https://api.crossref.org/works/10.1007/S13346-011-0022-6

21 January 2018

Pharmacokinetic Assessment of Dapivirine Vaginal Microbicide Gel in Healthy, HIV-Negative Women

1 reference

https://api.crossref.org/works/10.1007/S13346-011-0022-6

21 January 2018

Safety and Availability of Dapivirine (TMC120) Delivered from an Intravaginal Ring

1 reference

https://api.crossref.org/works/10.1007/S13346-011-0022-6

21 January 2018

Safety and pharmacokinetics of dapivirine delivery from matrix and reservoir intravaginal rings to HIV-negative women

1 reference

https://pubmed.ncbi.nlm.nih.gov/22708075

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of vaginal transmission of HIV-1 in hu-SCID mice by the non-nucleoside reverse transcriptase inhibitor TMC120 in a gel formulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22708075

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug Delivery Technology

44

9

24

author name string

M Hariharan

publication date

2009

1 reference

10.1007/S13346-011-0022-6

https://api.crossref.org/works/10.1007/S13346-011-0022-6

4 January 2025

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10.1007/S13346-011-0022-6

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

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