Calcific nodule morphogenesis by heart valve interstitial cells is strain dependent (Q36032728)

11 August 2017

Calcific nodule morphogenesis by heart valve interstitial cells is strain dependent (English)

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11 August 2017

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Charles I Fisher

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11 August 2017

Joseph Chen

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2

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11 August 2017

W David Merryman

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3

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11 August 2017

4 February 2012

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Biomechanics and Modeling in Mechanobiology

11 August 2017

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11 August 2017

12

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11 August 2017

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11 August 2017

5-17

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describes a project that uses

11 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3375394/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Calcific aortic valve disease: not simply a degenerative process: A review and agenda for research from the National Heart and Lung and Blood Institute Aortic Stenosis Working Group. Executive summary: Calcific aortic valve disease-2011 update.

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Cell-matrix interactions in the pathobiology of calcific aortic valve disease: critical roles for matricellular, matricrine, and matrix mechanics cues

2 October 2017

1 reference

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The aortic valve microenvironment and its role in calcific aortic valve disease

2 October 2017

1 reference

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Heart disease and stroke statistics--2011 update: a report from the American Heart Association

2 October 2017

1 reference

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Role of the Rho pathway in regulating valvular interstitial cell phenotype and nodule formation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375394

Elevated cyclic stretch induces aortic valve calcification in a bone morphogenic protein-dependent manner

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375394

Hemodynamic environments from opposing sides of human aortic valve leaflets evoke distinct endothelial phenotypes in vitro

2 October 2017

1 reference

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Regulation of valvular interstitial cell calcification by adhesive peptide sequences

2 October 2017

1 reference

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Mechanisms of aortic valve calcification: the LDL-density-radius theory: a translation from cell signaling to physiology

2 October 2017

1 reference

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Mechano-potential etiologies of aortic valve disease

2 October 2017

1 reference

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What modulates the aortic valve interstitial cell phenotype?

2 October 2017

1 reference

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Statins block calcific nodule formation of valvular interstitial cells by inhibiting alpha-smooth muscle actin expression

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375394

A computational model of aging and calcification in the aortic heart valve

2 October 2017

1 reference

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Role of the MAPK/ERK pathway in valvular interstitial cell calcification

2 October 2017

1 reference

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Identification and characterization of aortic valve mesenchymal progenitor cells with robust osteogenic calcification potential

2 October 2017

1 reference

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Fibrogenic fibroblasts increase intercellular adhesion strength by reinforcing individual OB-cadherin bonds

2 October 2017

1 reference

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Myofibroblast contraction activates latent TGF-beta1 from the extracellular matrix

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375394

Insights into degenerative aortic valve disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375394

Aortic valve stenosis: an active atheroinflammatory process

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375394

Synergistic effects of cyclic tension and transforming growth factor-beta1 on the aortic valve myofibroblast

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375394

An ex vivo study of the biological properties of porcine aortic valves in response to circumferential cyclic stretch

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375394

Focal adhesion size controls tension-dependent recruitment of alpha-smooth muscle actin to stress fibers

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375394

Mechanical stimulation and mitogen-activated protein kinase signaling independently regulate osteogenic differentiation and mineralization by calcifying vascular cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375394

Myofibroblast development is characterized by specific cell-cell adherens junctions.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375394

Myofibroblasts and mechano-regulation of connective tissue remodelling

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375394

Mechanical tension controls granulation tissue contractile activity and myofibroblast differentiation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375394

Intracellular Ca(2 ) accumulation is strain-dependent and correlates with apoptosis in aortic valve fibroblasts

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375394

Substrate properties influence calcification in valvular interstitial cell culture

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375394

Inhibition of calcifying nodule formation in cultured porcine aortic valve cells by nitric oxide donors.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375394

The effects of cellular contraction on aortic valve leaflet flexural stiffness.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375394

Calcification by valve interstitial cells is regulated by the stiffness of the extracellular matrix

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375394

Regulation of valvular interstitial cell calcification by components of the extracellular matrix

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375394

Transient, three-dimensional, multiscale simulations of the human aortic valve

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375394

Differences in tissue-remodeling potential of aortic and pulmonary heart valve interstitial cells

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375394

Stress distribution in a circular membrane with a central fixation.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375394

Activation of valvular interstitial cells is mediated by transforming growth factor-beta1 interactions with matrix molecules

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375394

Valvular myofibroblast activation by transforming growth factor-beta: implications for pathological extracellular matrix remodeling in heart valve disease.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375394

Redistribution of stress due to a circular hole in a nonlinear anisotropic membrane

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375394

Can progression of valvar aortic stenosis be predicted accurately?

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375394

Progression of aortic valve stenosis: TGF-beta1 is present in calcified aortic valve cusps and promotes aortic valve interstitial cell calcification via apoptosis

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375394

Mechanical stress as cause of aortic valve disease. Presentation of a new aortic root prosthesis

23 September 2018

1 reference

12 December 2020

Identification and characterization of calcifying valve cells from human and canine aortic valves

1 reference

12 December 2020

Applying controlled non-uniform deformation for in vitro studies of cell mechanobiology

1 reference

12 December 2020

Bone formation and inflammation in cardiac valves

1 reference

12 December 2020

Microstructural and biomechanical alterations of the human aorta as a function of age and location

1 reference

12 December 2020

Myofibroblast communication is controlled by intercellular mechanical coupling

1 reference

12 December 2020

Correlation between heart valve interstitial cell stiffness and transvalvular pressure: implications for collagen biosynthesis

1 reference

12 December 2020

β-catenin mediates mechanically regulated, transforming growth factor-β1-induced myofibroblast differentiation of aortic valve interstitial cells

1 reference

12 December 2020

Elevated cyclic stretch alters matrix remodeling in aortic valve cusps: implications for degenerative aortic valve disease

1 reference

12 December 2020

10.1007/S10237-012-0377-8

Identifiers

DOI

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11 August 2017

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11 August 2017

PubMed publication ID

22307683

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