DNA damage induces Chk1-dependent centrosome amplification. (Q36029906)

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30 December 2019

title

DNA damage induces Chk1-dependent centrosome amplification (English)

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30 December 2019

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1

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30 December 2019

Ciaran G Morrison

8

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30 December 2019

author name string

Helen Dodson

2

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30 December 2019

Andreas Merdes

3

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30 December 2019

Lorraine Cuffe

4

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30 December 2019

George Zachos

5

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30 December 2019

Mark Walker

6

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30 December 2019

David Gillespie

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30 December 2019

publication date

27 April 2007

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30 December 2019

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30 December 2019

volume

8

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30 December 2019

issue

6

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30 December 2019

page(s)

603-609

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NEDD1-dependent recruitment of the gamma-tubulin ring complex to the centrosome is necessary for centriole duplication and spindle assembly

30 December 2019

cites work

1 reference

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ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

2 October 2017

1 reference

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Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2002539

Chk1-dependent S-M checkpoint delay in vertebrate cells is linked to maintenance of viable replication structures.

2 October 2017

1 reference

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The forkhead-associated domain protein Cep170 interacts with Polo-like kinase 1 and serves as a marker for mature centrioles

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2002539

Centrosome amplification induced by DNA damage occurs during a prolonged G2 phase and involves ATM.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2002539

Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2002539

Centrosomes split in the presence of impaired DNA integrity during mitosis

2 October 2017

1 reference

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Chk1 and Chk2 kinases in checkpoint control and cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2002539

Centrosome number is controlled by a centrosome-intrinsic block to reduplication

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2002539

A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome

2 October 2017

1 reference

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2 October 2017

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Chk1-deficient tumour cells are viable but exhibit multiple checkpoint and survival defects

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2002539

Centrosome aberrations: cause or consequence of cancer progression?

2 October 2017

1 reference

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Assembly of centrosomal proteins and microtubule organization depends on PCM-1

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2002539

Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2002539

Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2002539

Centrosome amplification drives chromosomal instability in breast tumor development

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2002539

Expression of mutant telomerase in immortal telomerase-negative human cells results in cell cycle deregulation, nuclear and chromosomal abnormalities and rapid loss of viability

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2002539

Managing the centrosome numbers game: from chaos to stability in cancer cell division

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2002539

Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2002539

Aberrant cell cycle checkpoint function and early embryonic death in Chk1(-/-) mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2002539

The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2002539

Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2002539

Abnormal centrosome amplification in the absence of p53.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2002539

Dissociation of centrosome replication events from cycles of DNA synthesis and mitotic division in hydroxyurea-arrested Chinese hamster ovary cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2002539

Microtubule-organizing centers abnormal in number, structure, and nucleating activity in x-irradiated mammalian cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2002539

Centriole distribution during tripolar mitosis in Chinese hamster ovary cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2002539

Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2002539

Radiation-induced centrosome overduplication and multiple mitotic spindles in human tumor cells

23 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17468739

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mammalian recombination-repair genes XRCC2 and XRCC3 promote correct chromosome segregation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17468739

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Essential role of BETA2/NeuroD1 in development of the vestibular and auditory systems

1 reference

Crossref

https://api.crossref.org/works/10.1038/SJ.EMBOR.7400962

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.EMBOR.7400962

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30 December 2019

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30 December 2019

PubMed publication ID

17468739

1 reference