Wiskott Aldrich syndrome protein (WASP) and N-WASP are critical for T cell development. (Q36024288)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17878299 AND SRC:MED&resulttype=core&format=json

7 January 2020

title

Wiskott Aldrich syndrome protein (WASP) and N-WASP are critical for T cell development (English)

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7 January 2020

2

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7 January 2020

8

Ramnik Xavier

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7 January 2020

author name string

Vinicius Cotta-de-Almeida

1

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7 January 2020

Michel H Maillard

3

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7 January 2020

Dilek Onaldi

4

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7 January 2020

Heather Wachtel

5

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7 January 2020

Parool Meelu

6

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7 January 2020

Ung-il Chung

7

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7 January 2020

Frederick W Alt

9

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7 January 2020

Scott B Snapper

10

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7 January 2020

language of work or name

English

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publication date

18 September 2007

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Proceedings of the National Academy of Sciences of the United States of America

7 January 2020

published in

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7 January 2020

volume

104

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7 January 2020

issue

39

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7 January 2020

page(s)

15424-15429

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The Wiskott-Aldrich syndrome protein is required for the function of CD4( )CD25( )Foxp3( ) regulatory T cells

7 January 2020

cites work

1 reference

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Kruppel-like factor 2 regulates thymocyte and T-cell migration

2 October 2017

1 reference

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Thymic microenvironments for T cell differentiation and selection.

2 October 2017

1 reference

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Directed migration of positively selected thymocytes visualized in real time

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000553

WASP deficiency leads to global defects of directed leukocyte migration in vitro and in vivo

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000553

Cell migration and the control of post-natal T-cell lymphopoiesis in the thymus

2 October 2017

1 reference

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Vav1/2/3-null Mice Define an Essential Role for Vav Family Proteins in Lymphocyte Development and Activation but a Differential Requirement in MAPK Signaling in T and B Cells

2 October 2017

1 reference

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GTPases and T cell activation

2 October 2017

1 reference

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The Wiskott-Aldrich syndrome protein: forging the link between actin and cell activation

2 October 2017

1 reference

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Thymic selection revisited: how essential is it?

2 October 2017

1 reference

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The Wiskott-Aldrich syndrome protein acts downstream of CD2 and the CD2AP and PSTPIP1 adaptors to promote formation of the immunological synapse

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000553

Actin cytoskeletal dynamics in T lymphocyte activation and migration

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000553

Mechanism of recruitment of WASP to the immunological synapse and of its activation following TCR ligation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000553

Intrathymic T-cell migration: a combinatorial interplay of extracellular matrix and chemokines?

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000553

T-cell development and the CD4-CD8 lineage decision

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000553

WASp verprolin homology, cofilin homology, and acidic region domain-mediated actin polymerization is required for T cell development

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000553

N-WASP deficiency reveals distinct pathways for cell surface projections and microbial actin-based motility

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000553

WASP and WAVE family proteins: key molecules for rapid rearrangement of cortical actin filaments and cell movement

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000553

Role of chemokines in thymocyte development

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000553

The vav exchange factor is an essential regulator in actin-dependent receptor translocation to the lymphocyte-antigen-presenting cell interface

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000553

The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000553

T cell activation and the cytoskeleton

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000553

Antigen receptor-induced activation and cytoskeletal rearrangement are impaired in Wiskott-Aldrich syndrome protein-deficient lymphocytes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000553

Small GTPases in lymphocyte biology: Rho proteins take center stage

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000553

WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000553

RAG-2-deficient blastocyst complementation: an assay of gene function in lymphocyte development

2 October 2017

1 reference

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Inducible gene targeting in mice

2 October 2017

1 reference

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Differential roles for Wiskott-Aldrich syndrome protein in immune synapse formation and IL-2 production

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000553

CCR7-dependent cortex-to-medulla migration of positively selected thymocytes is essential for establishing central tolerance

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000553

WIP and WASP play complementary roles in T cell homing and chemotaxis to SDF-1alpha.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000553

Dynamic molecular interactions linking the T cell antigen receptor to the actin cytoskeleton.

23 September 2018

1 reference

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CCR7 signals are essential for cortex-medulla migration of developing thymocytes.

23 September 2018

1 reference

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CCR7 directs the migration of thymocytes into the thymic medulla

23 September 2018

1 reference

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Early deficit of lymphocytes in Wiskott-Aldrich syndrome: possible role of WASP in human lymphocyte maturation

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000553

A defect in hematopoietic stem cell migration explains the nonrandom X-chromosome inactivation in carriers of Wiskott-Aldrich syndrome

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000553

Gene therapy for Wiskott-Aldrich syndrome: rescue of T-cell signaling and amelioration of colitis upon transplantation of retrovirally transduced hematopoietic stem cells in mice

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000553

Wiskott-Aldrich syndrome protein regulates lipid raft dynamics during immunological synapse formation.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000553

Immature CD4( )CD8( ) thymocytes form a multifocal immunological synapse with sustained tyrosine phosphorylation

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000553

A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000553

Wiskott-Aldrich syndrome protein-deficient mice reveal a role for WASP in T but not B cell activation

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000553

Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000553

Wiskott-Aldrich syndrome protein deficiency leads to reduced B-cell adhesion, migration, and homing, and a delayed humoral immune response

23 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073/PNAS.0706881104

Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073/PNAS.0706881104

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073/PNAS.0706881104

A Requirement for the Rho-Family GTP Exchange Factor Vav in Positive and Negative Selection of Thymocytes

21 January 2018

1 reference

12 December 2020

Degree of TCR internalization and Ca2 flux correlates with thymocyte selection

1 reference

12 December 2020

Inefficient cell spreading and cytoskeletal polarization by CD4 CD8 thymocytes: regulation by the thymic environment

1 reference

12 December 2020

Control of pre-T cell proliferation and differentiation by the GTPase Rac-1

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0706881104

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17878299 AND SRC:MED&resulttype=core&format=json

7 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17878299 AND SRC:MED&resulttype=core&format=json

7 January 2020

PubMed publication ID

17878299

1 reference