Anterior gradient 2 is a binding stabilizer of hypoxia inducible factor-1α that enhances CoCl2 -induced doxorubicin resistance in breast cancer cells (Q36016235)

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English	Anterior gradient 2 is a binding stabilizer of hypoxia inducible factor-1α that enhances CoCl2 -induced doxorubicin resistance in breast cancer cells	scientific article

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scholarly article

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Europe PubMed Central

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11 August 2017

Anterior gradient 2 is a binding stabilizer of hypoxia inducible factor-1α that enhances CoCl2 -induced doxorubicin resistance in breast cancer cells (English)

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Europe PubMed Central

PMC publication ID

11 August 2017

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based on heuristic

inferred from title

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26079208 AND SRC:MED&resulttype=core&format=json

13 June 2020

author name string

Zheqi Li

1

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13 June 2020

Qi Zhu

2

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13 June 2020

Lingyun Hu

3

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13 June 2020

Hao Chen

4

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13 June 2020

Dawei Li

6

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13 June 2020

publication date

16 June 2015

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11 August 2017

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Europe PubMed Central

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13 June 2020

106

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13 June 2020

8

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13 June 2020

1041-1049

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26079208 AND SRC:MED&resulttype=core&format=json

13 June 2020

Trastuzumab plus adjuvant chemotherapy for human epidermal growth factor receptor 2-positive breast cancer: planned joint analysis of overall survival from NSABP B-31 and NCCTG N9831.

1 reference

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2 October 2017

AGR2, an endoplasmic reticulum protein, is secreted into the gastrointestinal mucus

1 reference

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2 October 2017

Involvement of HIF-1α activation in the doxorubicin resistance of human osteosarcoma cells

1 reference

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2 October 2017

AGR2 predicts tamoxifen resistance in postmenopausal breast cancer patients

1 reference

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2 October 2017

Inhibition of nuclear factor-κB activity enhanced chemosensitivity to cisplatin in human lung adeno-carcinoma A549 cells under chemical hypoxia conditions

1 reference

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2 October 2017

AGR2 expression is regulated by HIF-1 and contributes to growth and angiogenesis of glioblastoma

1 reference

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2 October 2017

The estrogen-regulated anterior gradient 2 (AGR2) protein in breast cancer: a potential drug target and biomarker

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4556394

2 October 2017

Mad1 mediates hypoxia-induced doxorubicin resistance in colon cancer cells by inhibiting mitochondrial function

1 reference

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2 October 2017

Six cycles of doxorubicin and cyclophosphamide or Paclitaxel are not superior to four cycles as adjuvant chemotherapy for breast cancer in women with zero to three positive axillary nodes: Cancer and Leukemia Group B 40101.

1 reference

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2 October 2017

Carbonic anhydrase IX is a predictive marker of doxorubicin resistance in early-stage breast cancer independent of HER2 and TOP2A amplification.

1 reference

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2 October 2017

HIF-1 activation induces doxorubicin resistance in MCF7 3-D spheroids via P-glycoprotein expression: a potential model of the chemo-resistance of invasive micropapillary carcinoma of the breast.

1 reference

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2 October 2017

A novel approach to cancer therapy using PX-478 as a HIF-1α inhibitor

1 reference

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2 October 2017

An integrative genomic analysis revealed the relevance of microRNA and gene expression for drug-resistance in human breast cancer cells

1 reference

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2 October 2017

RETRACTED ARTICLE: HIF-1-dependent expression of angiopoietin-like 4 and L1CAM mediates vascular metastasis of hypoxic breast cancer cells to the lungs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4556394

2 October 2017

AGR2, a mucinous ovarian cancer marker, promotes cell proliferation and migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4556394

2 October 2017

The anterior gradient 2 (AGR2) gene is overexpressed in prostate cancer and may be useful as a urine sediment marker for prostate cancer detection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4556394

2 October 2017

Expression and significance of hypoxia-inducible factor-1 alpha and MDR1/P-glycoprotein in human colon carcinoma tissue and cells

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2 October 2017

The protein disulfide isomerase AGR2 is essential for production of intestinal mucus

1 reference

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2 October 2017

The adenocarcinoma-associated antigen, AGR2, promotes tumor growth, cell migration, and cellular transformation

1 reference

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2 October 2017

Targeting HIF-1 for cancer therapy

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4556394

2 October 2017

Tumour hypoxia, chemotherapeutic resistance and hypoxia-related therapies.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4556394

2 October 2017

The von Hippel-Lindau tumor suppressor, hypoxia-inducible factor-1 (HIF-1) degradation, and cancer pathogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4556394

2 October 2017

CoCl2, a chemical inducer of hypoxia-inducible factor-1, and hypoxia reduce apoptotic cell death in hepatoma cell line HepG2.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4556394

2 October 2017

Hypoxia-inducible factor-1-dependent regulation of the multidrug resistance (MDR1) gene.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4556394

2 October 2017

Mitochondrial DNA damage and a hypoxic response are induced by CoCl(2) in rat neuronal PC12 cells

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Amplification and deletion of topoisomerase IIalpha associate with ErbB-2 amplification and affect sensitivity to topoisomerase II inhibitor doxorubicin in breast cancer

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Expression of the mutated p53 tumor suppressor protein and its molecular and biochemical characterization in multidrug resistant MCF-7/Adr human breast cancer cells

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Hypoxia and drug resistance

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The thioredoxin redox inhibitors 1-methylpropyl 2-imidazolyl disulfide and pleurotin inhibit hypoxia-induced factor 1alpha and vascular endothelial growth factor formation.

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Prognostic and predictive value of tumor-infiltrating lymphocytes in a phase III randomized adjuvant breast cancer trial in node-positive breast cancer comparing the addition of docetaxel to doxorubicin with doxorubicin-based chemotherapy: BIG 02-98

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Physiological stress induces the metastasis marker AGR2 in breast cancer cells

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The redox protein thioredoxin-1 (Trx-1) increases hypoxia-inducible factor 1alpha protein expression: Trx-1 overexpression results in increased vascular endothelial growth factor production and enhanced tumor angiogenesis

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UK and USA breast cancer deaths down 25% in year 2000 at ages 20-69 years.

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[Preparation, characterization and potential application of monoclonal antibody 18A4 against AGR2]

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12 December 2020

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Interaction between ROS and p38MAPK contributes to chemical hypoxia-induced injuries in PC12 cells

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https://pubmed.ncbi.nlm.nih.gov/26079208

12 December 2020

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inferred from PubMed ID database lookup

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10.1111/CAS.12714

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26079208 AND SRC:MED&resulttype=core&format=json

13 June 2020

PMC publication ID

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Europe PubMed Central

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13 June 2020

PubMed publication ID

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Europe PubMed Central

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13 June 2020

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