Misonidazole and CCNU: further evidence for a pharmacokinetic mechanism of chemosensitization and therapeutic gain (Q35991401)

11 August 2017

Misonidazole and CCNU: further evidence for a pharmacokinetic mechanism of chemosensitization and therapeutic gain (English)

1 reference

11 August 2017

1 reference

Lee FY

1

1 reference

11 August 2017

Workman P

series ordinal

2

1 reference

11 August 2017

language of work or name

English

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publication date

1 May 1984

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British Journal of Cancer

11 August 2017

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11 August 2017

49

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11 August 2017

5

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11 August 2017

579-585

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In vivo response of KHT sarcomas to combination chemotherapy with radiosensitizers and BCNU.

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976729

In vivo combination of misonidazole and the chemotherapeutic agent CCNU

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976729

Enhancement of CCNU cytotoxicity by misonidazole: possible therapeutic gain

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976729

Structure/activity relationships for the enhancement by electron-affinic drugs of the anti-tumour effect of CCNU

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976729

Potentiation of chemotherapy by hypoxic cell radiation sensitizers--a review.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976729

The mechanisms of cytotoxicity and chemosensitization by misonidazole and other nitroimidazoles.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976729

Chemosensitization by lipophilic nitroimidazoles

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976729

Modification of CCNU pharmacokinetics by misonidazole--a major mechanism of chemosensitization in mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976729

An investigation of the possibility of chemosensitization by clinically achievable concentrations of misonidazole

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976729

The effect of radiosensitizers on the pharmacokinetics of melphalan and cyclophosphamide in the mouse

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976729

Response of murine tumours to combinations of CCNU with misonidazole and other radiation sensitizers

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976729

Nitrosourea-misonidazole combination chemotherapy: Effect on KHT sarcomas, marrow stem cells and gut

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976729

Factors influencing the survival of rat brain tumor cells after in vitro treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976729

The effect of phenobarbital pretreatment on the antitumor activity of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU), 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) and 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidyl-1-nitrosourea (PCNU), and on the pl

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976729

The concept of drug dose for in vitro studies with chemotherapeutic agents

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976729

DNA cross-linking and monoadduct repair in nitrosourea-treated human tumour cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976729

Drug metabolism and chemosensitization. Nitroimidazoles as inhibitors of drug metabolism

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1976729

In vivo potentiation of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea by the radiation sensitizer benznidazole

23 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/6722006

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The effect of time between X-irradiation and chemotherapy on the growth of three solid mouse tumors—I. Adriamycin

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/6722006

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Effect of partition coefficient on the ability of nitroimidazoles to enhance the cytotoxicity of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/6722006

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/BJC.1984.92

1 reference

11 August 2017

1 reference

11 August 2017

PubMed publication ID

6722006

1 reference