Of mice and men: the benefits of caloric restriction, exercise, and mimetics. (Q35973671)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22210414 AND SRC:MED&resulttype=core&format=json

19 January 2020

title

Of mice and men: the benefits of caloric restriction, exercise, and mimetics (English)

1 reference

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19 January 2020

1 reference

4

1 reference

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19 January 2020

author name string

Evi M Mercken

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22210414 AND SRC:MED&resulttype=core&format=json

19 January 2020

Bethany A Carboneau

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22210414 AND SRC:MED&resulttype=core&format=json

19 January 2020

Susan M Krzysik-Walker

series ordinal

3

1 reference

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19 January 2020

publication date

20 December 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22210414 AND SRC:MED&resulttype=core&format=json

19 January 2020

published in

Ageing Research Reviews

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22210414 AND SRC:MED&resulttype=core&format=json

19 January 2020

volume

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22210414 AND SRC:MED&resulttype=core&format=json

19 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22210414 AND SRC:MED&resulttype=core&format=json

19 January 2020

page(s)

390-398

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22210414 AND SRC:MED&resulttype=core&format=json

Exercise and Diet, Independent of Weight Loss, Improve Cardiometabolic Risk Profile in Overweight and Obese Individuals

19 January 2020

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Exercise as a calorie restriction mimetic: implications for improving healthy aging and longevity

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Calorie restriction and endurance exercise share potent anti-inflammatory function in adipose tissues in ameliorating diet-induced obesity and insulin resistance in mice

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2 October 2017

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2 October 2017

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TOR signaling never gets old: aging, longevity and TORC1 activity.

2 October 2017

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2 October 2017

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2 October 2017

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SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Exercise: it's the real thing!

2 October 2017

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2 October 2017

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Effect of exercise intensity on abdominal fat loss during calorie restriction in overweight and obese postmenopausal women: a randomized, controlled trial.

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Caloric restriction alone and with exercise improves CVD risk in healthy non-obese individuals

2 October 2017

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Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span

2 October 2017

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Attenuation of sarcopenia by dietary restriction in rhesus monkeys

2 October 2017

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A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Lifelong exercise and mild (8%) caloric restriction attenuate age-induced alterations in plantaris muscle morphology, oxidative stress and IGF-1 in the Fischer-344 rat.

2 October 2017

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2 October 2017

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2 October 2017

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Exercise-induced alterations in muscle lipid metabolism improve insulin sensitivity

2 October 2017

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SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B

2 October 2017

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Effects of resveratrol on lifespan in Drosophila melanogaster and Caenorhabditis elegans

2 October 2017

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Effects of life-long caloric restriction and voluntary exercise on age-related changes in levels of catecholamine biosynthetic enzymes and angiotensin II receptors in the rat adrenal medulla and hypothalamus

2 October 2017

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Resveratrol stimulates glucose transport in C2C12 myotubes by activating AMP-activated protein kinase

2 October 2017

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Metformin and exercise reduce muscle FAT/CD36 and lipid accumulation and blunt the progression of high-fat diet-induced hyperglycemia

2 October 2017

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Exercise for prevention and treatment of cardiovascular disease, type 2 diabetes, and metabolic syndrome

2 October 2017

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Long-term low-protein, low-calorie diet and endurance exercise modulate metabolic factors associated with cancer risk

2 October 2017

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Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

2 October 2017

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Resveratrol improves health and survival of mice on a high-calorie diet

2 October 2017

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Effect of calorie restriction with or without exercise on insulin sensitivity, beta-cell function, fat cell size, and ectopic lipid in overweight subjects

2 October 2017

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Effect of long-term calorie restriction with adequate protein and micronutrients on thyroid hormones.

2 October 2017

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Calorie restriction mimetics: an emerging research field

2 October 2017

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Health benefits of physical activity: the evidence

2 October 2017

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Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate.

2 October 2017

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mTOR pathway inhibition attenuates skeletal muscle growth induced by stretching

2 October 2017

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Mechanism of induction of muscle protein degradation by angiotensin II.

2 October 2017

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Caloric restriction in humans: potential pitfalls and health concerns

2 October 2017

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Identification of potential caloric restriction mimetics by microarray profiling

2 October 2017

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Effect of metformin on life span and on the development of spontaneous mammary tumors in HER-2/neu transgenic mice

2 October 2017

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Mechanism of human SIRT1 activation by resveratrol

2 October 2017

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Substrate-specific activation of sirtuins by resveratrol

2 October 2017

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Induction of proteasome expression in skeletal muscle is attenuated by inhibitors of NF-kappaB activation

2 October 2017

1 reference

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An accelerated assay for the identification of lifespan-extending interventions in Drosophila melanogaster

2 October 2017

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Sirtuin activators mimic caloric restriction and delay ageing in metazoans

2 October 2017

1 reference

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Development of calorie restriction mimetics as a prolongevity strategy.

2 October 2017

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Improving survival with metformin: the evidence base today.

2 October 2017

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Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

2 October 2017

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Calorie restriction in rhesus monkeys

2 October 2017

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Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes

2 October 2017

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Metformin Increases AMP-Activated Protein Kinase Activity in Skeletal Muscle of Subjects With Type 2 Diabetes

2 October 2017

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Role of AMP-activated protein kinase in mechanism of metformin action

2 October 2017

1 reference

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Physical activity and all-cause mortality: what is the dose-response relation?

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Calorie restriction lowers body temperature in rhesus monkeys, consistent with a postulated anti-aging mechanism in rodents

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Metabolic effects of metformin in non-insulin-dependent diabetes mellitus

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

The retardation of aging in mice by dietary restriction: longevity, cancer, immunity and lifetime energy intake

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Exercise and longevity: studies on rats

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

The effect of retarded growth upon the length of life span and upon the ultimate body size. 1935

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Rapamycin (AY-22,989), a new antifungal antibiotic. I. Taxonomy of the producing streptomycete and isolation of the active principle

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Impact of Westernization on the nutrition of Japanese: changes in physique, cancer, longevity and centenarians

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Resveratrol prevents the wasting disorders of mechanical unloading by acting as a physical exercise mimetic in the rat.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Combined effects of short-term calorie restriction and exercise on insulin action in normal rats

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Metformin, but not exercise training, increases insulin responsiveness in skeletal muscle of Sprague-Dawley rats

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Dietary restriction increases insulin sensitivity and lowers blood glucose in rhesus monkeys

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Effect of exercise on longevity, body weight, locomotor performance, and passive-avoidance memory of C57BL/6J mice

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Interaction between exercise and food restriction: effects on longevity of male rats

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Modulatory effect of resveratrol on SIRT1, SIRT3, SIRT4, PGC1α and NAMPT gene expression profiles in wild-type adult zebrafish liver.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Effects of aging and gender on muscle mass and regulation of Akt-mTOR-p70s6k related signaling in the F344BN rat model

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Metformin extends life span of HER-2/neu transgenic mice and in combination with melatonin inhibits growth of transplantable tumors in vivo.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Biochemical and molecular mechanisms of aging: from model systems to human longevity. Preface.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Rapamycin administration in humans blocks the contraction-induced increase in skeletal muscle protein synthesis

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

The exercise pill--too good to be true?

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Suppression of the aging-associated decline in physical performance by a combination of resveratrol intake and habitual exercise in senescence-accelerated mice

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Metformin slows down aging and extends life span of female SHR mice.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Phosphatidylinositol-3-kinase is involved in the antihyperglycemic effect induced by resveratrol in streptozotocin-induced diabetic rats

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Impact of weight reduction on production of platelet-derived microparticles and fibrinolytic parameters in obesity.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Resveratrol, a red wine antioxidant, possesses an insulin-like effect in streptozotocin-induced diabetic rats

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Induction of protein degradation in skeletal muscle by a phorbol ester involves upregulation of the ubiquitin-proteasome proteolytic pathway

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Improved clinical outcomes associated with metformin in patients with diabetes and heart failure

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Skeletal myocyte hypertrophy requires mTOR kinase activity and S6K1.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Effects of metformin and rosiglitazone treatment on insulin signaling and glucose uptake in patients with newly diagnosed type 2 diabetes: a randomized controlled study

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Physical activity in the prevention of type 2 diabetes: the Finnish diabetes prevention study

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Resistance exercise increases muscle protein synthesis and translation of eukaryotic initiation factor 2Bepsilon mRNA in a mammalian target of rapamycin-dependent manner

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Strength training increases insulin-mediated glucose uptake, GLUT4 content, and insulin signaling in skeletal muscle in patients with type 2 diabetes.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Age-associated changes in skeletal muscles and their effect on mobility: an operational diagnosis of sarcopenia

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Hunger diet on alternate days in the nutrition of the aged

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Rosiglitazone but not metformin enhances insulin- and exercise-stimulated skeletal muscle glucose uptake in patients with newly diagnosed type 2 diabetes

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Effects of dietary caloric restriction and aging on thyroid hormones of rhesus monkeys

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Exercise adds to metformin and acarbose efficacy in db/db mice

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Calorie restriction in nonhuman primates: effects on diabetes and cardiovascular disease risk

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Body fat distribution with long-term dietary restriction in adult male rhesus macaques.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Aggressive weight reduction treatment in the management of type 2 diabetes.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356510

Hepatic oxidative stress during aging: effects of 8% long-term calorie restriction and lifelong exercise

24 September 2018

1 reference

12 December 2020

Short-term effects of metformin in type 2 diabetes

1 reference

12 December 2020

Early-onset calorie restriction conserves fiber number in aging rat skeletal muscle

1 reference

12 December 2020

Dietary restriction in mice beginning at 1 year of age: effect on life-span and spontaneous cancer incidence

1 reference

12 December 2020

Resveratrol does not ameliorate muscle wasting in different types of cancer cachexia models

1 reference

12 December 2020

Effect of voluntary exercise on longevity of rats

1 reference

12 December 2020

Calorie restriction or exercise: effects on coronary heart disease risk factors. A randomized, controlled trial

1 reference

12 December 2020

Reduction of premature mortality by high physical activity: a 20-year follow-up of middle-aged Finnish men

1 reference

12 December 2020

Long-term low-calorie low-protein vegan diet and endurance exercise are associated with low cardiometabolic risk

1 reference

12 December 2020

10.1016/J.ARR.2011.11.005

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22210414 AND SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22210414 AND SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

22210414

1 reference