Chemotaxis receptors and signaling (Q35925892)

11 August 2017

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title

Chemotaxis receptors and signaling (English)

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11 August 2017

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Aaron F Miller

1

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11 August 2017

Joseph J Falke

series ordinal

2

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11 August 2017

publication date

1 January 2004

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Advances in Protein Chemistry

11 August 2017

published in

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11 August 2017

volume

68

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11 August 2017

page(s)

393-444

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CXC Chemokines Bind to Unique Sets of Selectivity Determinants That Can Function Independently and Are Broadly Distributed on Multiple Domains of Human Interleukin-8 Receptor B

11 August 2017

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Characterization of the molecular interactions of interleukin-8 (CXCL8), growth related oncogen alpha (CXCL1) and a non-peptide antagonist (SB 225002) with the human CXCR2.

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Molecular cloning and functional expression of two monocyte chemoattractant protein 1 receptors reveals alternative splicing of the carboxyl-terminal tails

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Signaling pathways at the leading edge of chemotaxing cells

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Constitutive activation of opsin: influence of charge at position 134 and size at position 296.

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Arginine 206 of the C5a Receptor Is Critical for Ligand Recognition and Receptor Activation by C-terminal Hexapeptide Analogs

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Role of extracellular disulfide-bonded cysteines in the ligand binding function of the beta 2-adrenergic receptor

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A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5

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Odorant receptors: a plethora of G-protein-coupled receptors

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Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin

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7 January 2021

G protein-coupled receptor rhodopsin: a prospectus

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C5a receptor oligomerization. II. Fluorescence resonance energy transfer studies of a human G protein-coupled receptor expressed in yeast

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7 January 2021

Rhodopsin dimers in native disc membranes

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Formyl peptide chemoattractants: a model of the receptor on rabbit neutrophils

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Further studies on the structural requirements for synthetic peptide chemoattractants

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Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis

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The chemotactic receptor for human C5a anaphylatoxin

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Uncovering molecular mechanisms involved in activation of G protein-coupled receptors

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Agonist-induced conformational changes in the G-protein-coupling domain of the beta 2 adrenergic receptor

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7 January 2021

The TXP motif in the second transmembrane helix of CCR5. A structural determinant of chemokine-induced activation

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7 January 2021

Activation of CCR5 by chemokines involves an aromatic cluster between transmembrane helices 2 and 3.

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7 January 2021

Evolutionary relationships among G protein-coupled receptors using a clustered database approach

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7 January 2021

Mutational and computational analysis of the alpha(1b)-adrenergic receptor. Involvement of basic and hydrophobic residues in receptor activation and G protein coupling

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7 January 2021

A single amino acid substitution (N297A) in the conserved NPXXY sequence of the human N-formyl peptide receptor results in inhibition of desensitization and endocytosis, and a dose-dependent shift in p42/44 mitogen-activated protein kinase activatio

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7 January 2021

Experimental evidence for lack of homodimerization of the G protein-coupled human N-formyl peptide receptor

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7 January 2021

Role of the first extracellular loop in the functional activation of CCR2. The first extracellular loop contains distinct domains necessary for both agonist binding and transmembrane signaling

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7 January 2021

Differential roles of the NPXXY motif in formyl peptide receptor signaling

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A peptide derived from a beta2-adrenergic receptor transmembrane domain inhibits both receptor dimerization and activation.

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7 January 2021

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Annotating the human proteome: the Human Proteome Survey Database (HumanPSD) and an in-depth target database for G protein-coupled receptors (GPCR-PD) from Incyte Genomics

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7 January 2021

Activating and inactivating mutations in N- and C-terminal i3 loop junctions of muscarinic acetylcholine Hm1 receptors

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7 January 2021

Structure and Functional Expression of a Human Interleukin-8 Receptor

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The local environment at the cytoplasmic end of TM6 of the mu opioid receptor differs from those of rhodopsin and monoamine receptors: introduction of an ionic lock between the cytoplasmic ends of helices 3 and 6 by a L6.30(275)E mutation inactivate

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7 January 2021

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7 January 2021

Identifying conformational changes with site-directed spin labeling

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7 January 2021

Structure-function relationships of human C5a and C5aR.

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Crystallisation of membrane proteins mediated by antibody fragments

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Tumor suppressor PTEN mediates sensing of chemoattractant gradients.

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Constitutive Agonist-independent CCR5 Oligomerization and Antibody-mediated Clustering Occurring at Physiological Levels of Receptors

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7 January 2021

Mutations of F110 and C126 of the formyl peptide receptor interfere with G-protein coupling and chemotaxis

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7 January 2021

Interleukin 8, neutrophil-activating peptide-2 and GRO-alpha bind to and elicit cell activation via specific and different amino acid residues of CXCR2.

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7 January 2021

Structure and function in rhodopsin: Rhodopsin mutants with a neutral amino acid at E134 have a partially activated conformation in the dark state

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7 January 2021

C5a receptor oligomerization. I. Disulfide trapping reveals oligomers and potential contact surfaces in a G protein-coupled receptor

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Interleukin 8-stimulated phosphatidylinositol-3-kinase activity regulates the migration of human neutrophils independent of extracellular signal-regulated kinase and p38 mitogen-activated protein kinases

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7 January 2021

Probing the "message:address" sites for chemoattractant binding to the C5a receptor. Mutagenesis of hydrophilic and proline residues within the transmembrane segments

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7 January 2021

A proposed structure for transmembrane segment 7 of G protein-coupled receptors incorporating an asn-Pro/Asp-Pro motif

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7 January 2021

Guanine nucleotides modulate the binding affinity of the oligopeptide chemoattractant receptor on human polymorphonuclear leukocytes

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7 January 2021

Functional characterization of a human receptor for neuropeptide FF and related peptides

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Characterization of sequence determinants within the carboxyl-terminal domain of chemokine receptor CCR5 that regulate signaling and receptor internalization

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7 January 2021

The Three-dimensional Structure of Bovine Rhodopsin Determined by Electron Cryomicroscopy

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Characterisation of an improved two-dimensional p22121 crystal from bovine rhodopsin.

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The role of receptor kinases and arrestins in G protein-coupled receptor regulation

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CC chemokine MIP-1 beta can function as a monomer and depends on Phe13 for receptor binding

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7 January 2021

Formyl-peptide receptors revisited

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7 January 2021

Inhibition of cell surface expression by mutant receptors demonstrates that D2 dopamine receptors exist as oligomers in the cell

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7 January 2021

D2 dopamine receptor homodimerization is mediated by multiple sites of interaction, including an intermolecular interaction involving transmembrane domain 4.

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7 January 2021

Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction

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7 January 2021

Organization of the G protein-coupled receptors rhodopsin and opsin in native membranes

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7 January 2021

RasC is required for optimal activation of adenylyl cyclase and Akt/PKB during aggregation

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7 January 2021

Chemokine receptors: keys to AIDS pathogenesis?

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Chemokines and chemokine receptors: biology and clinical relevance in inflammation and AIDS.

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Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase gamma

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7 January 2021

Monomeric variants of IL-8: effects of side chain substitutions and solution conditions upon dimer formation

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Activation and targeting of mitogen-activated protein kinases by G-protein-coupled receptors.

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7 January 2021

Src tyrosine kinase is a novel direct effector of G proteins.

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7 January 2021

Chemokines: immunology's high impact factors

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7 January 2021

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7 January 2021

Intracellular signalling pathways induced by chemokines in natural killer cells

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7 January 2021

Chemokine receptor homo- or heterodimerization activates distinct signaling pathways

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7 January 2021

Receptor activation: what does the rhodopsin structure tell us?

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7 January 2021

Leading the way: Directional sensing through phosphatidylinositol 3-kinase and other signaling pathways.

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7 January 2021

Identification of Putative Sites of Interaction between the Human Formyl Peptide Receptor and G Protein

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7 January 2021

Identification of a ligand binding site in the human neutrophil formyl peptide receptor using a site-specific fluorescent photoaffinity label and mass spectrometry.

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7 January 2021

Characterization of the Binding Site on the Formyl Peptide Receptor Using Three Receptor Mutants and Analogs of Met-Leu-Phe and Met-Met-Trp-Leu-Leu

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7 January 2021

The amino-terminal domain of CCR2 is both necessary and sufficient for high affinity binding of monocyte chemoattractant protein 1. Receptor activation by a pseudo-tethered ligand

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7 January 2021

The molecular biology of leukocyte chemoattractant receptors

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7 January 2021

International Union of Pharmacology. XXX. Update on chemokine receptor nomenclature

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7 January 2021

Cloning of complementary DNA encoding a functional human interleukin-8 receptor

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7 January 2021

Sequence and organization of the human N-formyl peptide receptor-encoding gene

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7 January 2021

Molecular anatomy of CCR5 engagement by physiologic and viral chemokines and HIV-1 envelope glycoproteins: differences in primary structural requirements for RANTES, MIP-1 alpha, and vMIP-II Binding

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7 January 2021

Receptors induce chemotaxis by releasing the βγ subunit of G i , not by activating G q or G s

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7 January 2021

Common and distinct intracellular signaling pathways in human neutrophils utilized by platelet activating factor and FMLP.

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7 January 2021

Eotaxin is a natural antagonist for CCR2 and an agonist for CCR5

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7 January 2021

Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase gamma

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7 January 2021

Crystal structure of rhodopsin: A G protein-coupled receptor

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7 January 2021

A cell's sense of direction

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7 January 2021

Cyclic ADP-ribose production by CD38 regulates intracellular calcium release, extracellular calcium influx and chemotaxis in neutrophils and is required for bacterial clearance in vivo

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7 January 2021

Conserved helix 7 tyrosine acts as a multistate conformational switch in the 5HT2C receptor. Identification of a novel "locked-on" phenotype and double revertant mutations.

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7 January 2021

Desensitization of N-formylpeptide receptor-mediated activation is dependent upon receptor phosphorylation

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7 January 2021

Multiple activation steps of the N-formyl peptide receptor

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7 January 2021

Binding of low affinity N-formyl peptide receptors to G protein. Characterization of a novel inactive receptor intermediate

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7 January 2021

The N-formyl peptide receptor: a model for the study of chemoattractant receptor structure and function

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7 January 2021

Role of palmitoylation/depalmitoylation reactions in G-protein-coupled receptor function

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7 January 2021

Rhodopsin mutation G90D and a molecular mechanism for congenital night blindness

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7 January 2021

Platelet activating factor stimulates intracellular calcium transients in human neutrophils: involvement of endogenous 5-lipoxygenase products

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7 January 2021

The chemokine monocyte chemoattractant protein-1 induces functional responses through dimerization of its receptor CCR2

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7 January 2021

Structure of rhodopsin and the superfamily of seven-helical receptors: the same and not the same

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https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Functional differences between monocyte chemotactic protein-1 receptor A and monocyte chemotactic protein-1 receptor B expressed in a Jurkat T cell

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Identification of a Structural Element in Phospholipase C β2 That Interacts with G Protein βγ Subunits

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Hinges, swivels and switches: the role of prolines in signalling via transmembrane alpha-helices

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

The activation process of the alpha1B-adrenergic receptor: potential role of protonation and hydrophobicity of a highly conserved aspartate

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Defective Gi protein coupling in two formyl peptide receptor mutants associated with localized juvenile periodontitis

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

The human formyl peptide receptor as model system for constitutively active G-protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Evidence for a model of agonist-induced activation of 5-hydroxytryptamine 2A serotonin receptors that involves the disruption of a strong ionic interaction between helices 3 and 6.

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Beta2 adrenergic receptor activation. Modulation of the proline kink in transmembrane 6 by a rotamer toggle switch

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Two-site binding of C5a by its receptor: an alternative binding paradigm for G protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Constitutive "light" adaptation in rods from G90D rhodopsin: a mechanism for human congenital nightblindness without rod cell loss.

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Structure of a CXC chemokine-receptor fragment in complex with interleukin-8

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Receptor-coupled activation of phosphoinositide-specific phospholipase C by an N protein

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Hydrophilic residues at position 3 highlight unforeseen features of the fMLP receptor pocket

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

G protein mechanisms: insights from structural analysis

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Identification of a signal transduction switch in the chemokine receptor CXCR1.

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Identification of G protein-coupled receptor genes from the human genome sequence

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Dancing to the tune of chemokines

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Infection of cells expressing CXCR4 mutants lacking N-glycosylation at the N-terminal extracellular domain is enhanced for R5X4-dualtropic human immunodeficiency virus type-1.

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Ligand-independent CXCR2 dimerization

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5.

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Arrangement of rhodopsin transmembrane α-helices

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Prediction of structure and function of G protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Role of guanine nucleotide regulatory protein in polyphosphoinositide degradation and activation of phagocytic leukocytes by chemoattractants

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

HIV-1 infection through the CCR5 receptor is blocked by receptor dimerization.

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Three-dimensional representations of G protein-coupled receptor structures and mechanisms

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Lipid products of PI(3)Ks maintain persistent cell polarity and directed motility in neutrophils

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

A PtdInsP(3)- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Macrophage-tropic HIV and SIV envelope proteins induce a signal through the CCR5 chemokine receptor

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Critical role of N-terminal N-glycosylation for proper folding of the human formyl peptide receptor

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Functional differences between human formyl peptide receptor isoforms 26, 98, and G6.

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Structure, function and cellular expression of complement anaphylatoxin receptors

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Constitutive activation and endocytosis of the complement factor 5a receptor: evidence for multiple activated conformations of a G protein-coupled receptor

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Locomotion and chemotaxis of lymphocytes

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

G protein-coupled signal transduction pathways for interleukin-8

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5.

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Discrete steps in binding and signaling of interleukin-8 with its receptor

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Two Basic Amino Acids in the Second Inner Loop of the Interleukin-8 Receptor Are Essential for Gα16 Coupling

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Purification of a human monocyte-derived neutrophil chemotactic factor that has peptide sequence similarity to other host defense cytokines

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Structural definition of the C5a C terminus by two-dimensional nuclear magnetic resonance spectroscopy

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Chemokines: a new classification system and their role in immunity

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

Tertiary structure of human complement component C5a in solution from nuclear magnetic resonance data

1 reference

https://api.crossref.org/works/10.1016/S0065-3233(04)68011-9

7 January 2021

10.1016/S0065-3233(04)68011-9

Identifiers

DOI

1 reference

release_fmli2sl6xre35behovbnkd7rcm

11 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/fmli2sl6xre35behovbnkd7rcm

24 November 2022

mapped directly with Wikidata item

1 reference