Glucose-dependent acetylation of Rictor promotes targeted cancer therapy resistance (Q35910243)

11 August 2017

Glucose-dependent acetylation of Rictor promotes targeted cancer therapy resistance (English)

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11 August 2017

7

Timothy F Cloughesy

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11 August 2017

Kenta Masui

1

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11 August 2017

Kazuhiro Tanaka

2

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11 August 2017

Shiro Ikegami

3

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11 August 2017

Genaro R Villa

4

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11 August 2017

Huijun Yang

5

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11 August 2017

William H Yong

6

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11 August 2017

Kanato Yamagata

8

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11 August 2017

Nobutaka Arai

9

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11 August 2017

Webster K Cavenee

10

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11 August 2017

Paul S Mischel

11

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11 August 2017

language of work or name

English

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publication date

13 July 2015

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Proceedings of the National Academy of Sciences of the United States of America

11 August 2017

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11 August 2017

112

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11 August 2017

30

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11 August 2017

9406-9411

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describes a project that uses

11 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4522814/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Acetate dependence of tumors

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Acetate fuels the cancer engine.

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Histone deacetylase inhibitors promote glioma cell death by G2 checkpoint abrogation leading to mitotic catastrophe.

11 July 2018

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Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation

11 July 2018

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mTORC2 in the center of cancer metabolic reprogramming

11 July 2018

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Protein kinase D1 mediates class IIa histone deacetylase phosphorylation and nuclear extrusion in intestinal epithelial cells: role in mitogenic signaling

11 July 2018

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mTOR target NDRG1 confers MGMT-dependent resistance to alkylating chemotherapy

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11 July 2018

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mTOR complex 2 controls glycolytic metabolism in glioblastoma through FoxO acetylation and upregulation of c-Myc

11 July 2018

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mTORC1 status dictates tumor response to targeted therapeutics.

11 July 2018

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Acetylation control of cancer cell metabolism.

11 July 2018

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Metabolic complications with the use of mTOR inhibitors for cancer therapy

11 July 2018

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Influence of metabolism on epigenetics and disease

11 July 2018

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Cancer cell metabolism: one hallmark, many faces.

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Mechanistic insights into the regulation of metabolic enzymes by acetylation

11 July 2018

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Metabolic regulation of epigenetics

11 July 2018

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ASEB: a web server for KAT-specific acetylation site prediction.

11 July 2018

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Links between metabolism and cancer

11 July 2018

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Metabolic reprogramming: a cancer hallmark even warburg did not anticipate

11 July 2018

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Cellular Metabolism and Disease: What Do Metabolic Outliers Teach Us?

11 July 2018

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Oncogenic EGFR signaling activates an mTORC2-NF-κB pathway that promotes chemotherapy resistance

11 July 2018

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Molecular pathology in adult high‐grade gliomas: from molecular diagnostics to target therapies

11 July 2018

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Multiple site acetylation of Rictor stimulates mammalian target of rapamycin complex 2 (mTORC2)-dependent phosphorylation of Akt protein

11 July 2018

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Characterization and prediction of lysine (K)-acetyl-transferase specific acetylation sites

11 July 2018

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On Acetyl-CoA as a Gauge of Cellular Metabolic State

11 July 2018

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Acetyl-CoA induces cell growth and proliferation by promoting the acetylation of histones at growth genes.

11 July 2018

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Hallmarks of Cancer: The Next Generation

11 July 2018

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Regulation of cellular metabolism by protein lysine acetylation

11 July 2018

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Mutant EGFR is required for maintenance of glioma growth in vivo, and its ablation leads to escape from receptor dependence

11 July 2018

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Lysine acetylation targets protein complexes and co-regulates major cellular functions

11 July 2018

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ATP-citrate lyase links cellular metabolism to histone acetylation

11 July 2018

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Understanding the Warburg effect: the metabolic requirements of cell proliferation

11 July 2018

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The molecular determinants of de novo nucleotide biosynthesis in cancer cells

11 July 2018

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mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice

11 July 2018

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Association between hyperglycemia and survival in patients with newly diagnosed glioblastoma

11 July 2018

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ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer.

11 July 2018

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Oncogene addiction: setting the stage for molecularly targeted cancer therapy

11 July 2018

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Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522814

Determination of the specific substrate sequence motifs of protein kinase C isozymes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522814

Epigenetic regulation of EMT: the Snail story

11 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073/PNAS.1511759112

21 January 2018

Identifiers

DOI

10.1073/PNAS.1511759112

1 reference

11 August 2017

0 references

1 reference

11 August 2017

PubMed publication ID

26170313

1 reference