Human immunodeficiency virus type 1 reverse transcriptase: role of Tyr115 in deoxynucleotide binding and misinsertion fidelity of DNA synthesis (Q35907177)

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scientific article published in August 1996

Language	Label	Description	Also known as
English	Human immunodeficiency virus type 1 reverse transcriptase: role of Tyr115 in deoxynucleotide binding and misinsertion fidelity of DNA synthesis	scientific article published in August 1996

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Human immunodeficiency virus type 1 reverse transcriptase: role of Tyr115 in deoxynucleotide binding and misinsertion fidelity of DNA synthesis (English)

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

author name string

Martín-Hernández AM

1

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Domingo E

2

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Menéndez-Arias L

3

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

language of work or name

0 references

publication date

1 August 1996

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

The EMBO Journal

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

15

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

16

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

4434-4442

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

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Resistance of clinical isolates of human immunodeficiency virus to antiretroviral agents

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Mutational studies of human DNA polymerase alpha. Identification of residues critical for deoxynucleotide binding and misinsertion fidelity of DNA synthesis.

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Identification of the nucleotide binding site of HIV-1 reverse transcriptase using dTTP as a photoaffinity label

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E. coli DNA polymerase I as a reverse transcriptase

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Human immunodeficiency virus type 1 reverse transcriptase tG:T mispair formation on RNA and DNA templates with mismatched primers: a kinetic and thermodynamic study.

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Structure of HIV-1 reverse transcriptase in a complex with the non-nucleoside inhibitor alpha-APA R 95845 at 2.8 A resolution

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Mechanism of inhibition of HIV-1 reverse transcriptase by non-nucleoside inhibitors

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Human immunodeficiency virus-1 reverse transcriptase heterodimer stability

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Misincorporation and mispaired primer extension by human immunodeficiency virus reverse transcriptase

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Sensitivity of wild-type human immunodeficiency virus type 1 reverse transcriptase to dideoxynucleotides depends on template length; the sensitivity of drug-resistant mutants does not.

1 reference

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Interactions between drug resistance mutations in human immunodeficiency virus type 1 reverse transcriptase

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Elementary steps in the DNA polymerase I reaction pathway

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DNA polymerase insertion fidelity. Gel assay for site-specific kinetics

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Complete nucleotide sequence of the AIDS virus, HTLV-III

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Identification of four conserved motifs among the RNA-dependent polymerase encoding elements

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Extension of mismatched 3' termini of DNA is a major determinant of the infidelity of human immunodeficiency virus type 1 reverse transcriptase.

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Co-expression of the subunits of the heterodimer of HIV-1 reverse transcriptase in Escherichia coli.

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Substrate binding in human immunodeficiency virus reverse transcriptase. An analysis of pyridoxal 5'-phosphate sensitivity and identification of lysine 263 in the substrate-binding domain

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Human immunodeficiency virus 1 reverse transcriptase. Template binding, processivity, strand displacement synthesis, and template switching

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Fidelity of human immunodeficiency virus type I reverse transcriptase in copying natural DNA.

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The accuracy of reverse transcriptase from HIV-1.

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Characterization of highly immunogenic p66/p51 as the reverse transcriptase of HTLV-III/LAV.

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A general structure for DNA-dependent DNA polymerases.

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Human immunodeficiency virus reverse transcriptase. Effect of primer length on template-primer binding

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A possible role for cysteine residues in the fidelity of DNA synthesis exhibited by the reverse transcriptases of human immunodeficiency viruses type 1 and type 2

1 reference

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Phi 29 DNA polymerase active site. Mutants in conserved residues Tyr254 and Tyr390 are affected in dNTP binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/8861970

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based on heuristic

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based on heuristic

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Identifiers

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

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