Glycomics: a pathway to a class of new and improved therapeutics (Q35906116)

11 August 2017

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title

Glycomics: a pathway to a class of new and improved therapeutics (English)

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11 August 2017

Zachary Shriver

1

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11 August 2017

S Raguram

series ordinal

2

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11 August 2017

Ram Sasisekharan

series ordinal

3

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11 August 2017

publication date

1 October 2004

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Nature Reviews Drug Discovery

11 August 2017

published in

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11 August 2017

volume

3

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11 August 2017

issue

10

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11 August 2017

page(s)

863-873

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Transfection of a human gene that corrects the Lec1 glycosylation defect: evidence for transfer of the structural gene for N-acetylglucosaminyltransferase I.

11 August 2017

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Exploring the glycan repertoire of genetically modified mice by isolation and profiling of the major glycan classes and nano-NMR analysis of glycan mixtures

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Sequencing complex polysaccharides

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A novel computational approach to integrate NMR spectroscopy and capillary electrophoresis for structure assignment of heparin and heparan sulfate oligosaccharides

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Carbohydrate microarrays for the recognition of cross-reactive molecular markers of microbes and host cells

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Direct isolation and sequencing of specific protein-binding glycosaminoglycans

31 March 2020

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Intact cell adhesion to glycan microarrays

31 March 2020

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Synthesis of sugar arrays in microtiter plate

31 March 2020

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Automated solid-phase synthesis of oligosaccharides

31 March 2020

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A Programmable One‐Pot Oligosaccharide Synthesis for Diversifying the Sugar Domains of Natural Products: A Case Study of Vancomycin

31 March 2020

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A new strategy for the synthesis of glycoproteins.

31 March 2020

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Production of complex human glycoproteins in yeast

31 March 2020

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In vivo modulated N-acyl side chain of N-acetylneuraminic acid modulates the cell contact-dependent inhibition of growth

31 March 2020

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Incorporation of azides into recombinant proteins for chemoselective modification by the Staudinger ligation

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Expanding the diversity of unnatural cell-surface sialic acids

31 March 2020

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A chemical approach for identifying O-GlcNAc-modified proteins in cells

31 March 2020

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A metabolic labeling approach toward proteomic analysis of mucin-type O-linked glycosylation

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31 March 2020

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Synthesis of thrombin-inhibiting heparin mimetics without side effects

31 March 2020

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A role for 3-O-sulfated heparan sulfate in cell fusion induced by herpes simplex virus type 1.

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The heparins and cancer

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Heparan sulfate regulates amyloid precursor protein processing by BACE1, the Alzheimer's beta-secretase

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31 March 2020

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31 March 2020

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Dynamic regulation of tumor growth and metastasis by heparan sulfate glycosaminoglycans

31 March 2020

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Selectin-mucin interactions as a probable molecular explanation for the association of Trousseau syndrome with mucinous adenocarcinomas

31 March 2020

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Emerging views of heparan sulfate glycosaminoglycan structure/activity relationships modulating dynamic biological functions

31 March 2020

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Developing a taste for sweets

31 March 2020

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Siglecs: sialic-acid-binding immunoglobulin-like lectins in cell-cell interactions and signalling.

31 March 2020

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Chemical synthesis of normal and transformed PSA glycopeptides

31 March 2020

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Sequencing of 3-O sulfate containing heparin decasaccharides with a partial antithrombin III binding site

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRD1521

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11 August 2017

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