A conserved structural mechanism of NMDA receptor inhibition: A comparison of ifenprodil and zinc. (Q35894314)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26170175 AND SRC:MED&resulttype=core&format=json

19 February 2020

title

A conserved structural mechanism of NMDA receptor inhibition: A comparison of ifenprodil and zinc (English)

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19 February 2020

2

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19 February 2020

author name string

Rita E Sirrieh

series ordinal

1

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19 February 2020

Vasanthi Jayaraman

series ordinal

3

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19 February 2020

language of work or name

1 reference

13 July 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26170175 AND SRC:MED&resulttype=core&format=json

The Journal of General Physiology

19 February 2020

published in

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19 February 2020

volume

146

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19 February 2020

issue

2

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19 February 2020

page(s)

173-181

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Subtype-dependent N-methyl-D-aspartate receptor amino-terminal domain conformations and modulation by spermine.

19 February 2020

cites work

1 reference

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Context-dependent GluN2B-selective inhibitors of NMDA receptor function are neuroprotective with minimal side effects

11 July 2018

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Stargazin promotes closure of the AMPA receptor ligand-binding domain

11 July 2018

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Luminescence resonance energy transfer to study conformational changes in membrane proteins expressed in mammalian cells

11 July 2018

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Amino-terminal domain tetramer organization and structural effects of zinc binding in the N-methyl-D-aspartate (NMDA) receptor.

11 July 2018

1 reference

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NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease

11 July 2018

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Ifenprodil effects on GluN2B-containing glutamate receptors.

11 July 2018

1 reference

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Structural changes of regulatory domain heterodimer of N-methyl-D-aspartate receptor subunits GluN1 and GluN2B through the binding of spermine and ifenprodil

11 July 2018

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Amino-terminal ligands prolong NMDA Receptor-mediated EPSCs

11 July 2018

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Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors

11 July 2018

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Zinc effects on NMDA receptor gating kinetics.

11 July 2018

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Glutamate receptor ion channels: structure, regulation, and function

11 July 2018

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Subunit arrangement in N-methyl-D-aspartate (NMDA) receptors

11 July 2018

1 reference

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Structure of the zinc-bound amino-terminal domain of the NMDA receptor NR2B subunit

11 July 2018

1 reference

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Control of NMDA receptor function by the NR2 subunit amino-terminal domain

11 July 2018

1 reference

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Mechanism of differential control of NMDA receptor activity by NR2 subunits

11 July 2018

1 reference

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LRET investigations of conformational changes in the ligand binding domain of a functional AMPA receptor

11 July 2018

1 reference

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Allosteric interaction between zinc and glutamate binding domains on NR2A causes desensitization of NMDA receptors

11 July 2018

1 reference

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Allosteric interaction between the amino terminal domain and the ligand binding domain of NR2A.

11 July 2018

1 reference

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Molecular determinants of coordinated proton and zinc inhibition of N-methyl-D-aspartate NR1/NR2A receptors

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516779

A critical role of the N-methyl-D-aspartate (NMDA) receptor subunit (NR) 2A in the expression of redox sensitivity of NR1/NR2A recombinant NMDA receptors.

11 July 2018

1 reference

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Transient expression of functional NMDA receptors in mammalian cells

11 July 2018

1 reference

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High-Affinity Zinc Inhibition of NMDA NR1–NR2A Receptors

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516779

Influence of extracellular pH on inhibition by ifenprodil at N-methyl-D-aspartate receptors in Xenopus oocytes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516779

Interactions between ifenprodil and the NR2B subunit of the N-methyl-D-aspartate receptor

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516779

Control of proton sensitivity of the NMDA receptor by RNA splicing and polyamines

11 July 2018

1 reference

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The N-terminal domains of both NR1 and NR2 subunits determine allosteric Zn2 inhibition and glycine affinity of N-methyl-D-aspartate receptors.

11 July 2018

1 reference

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The micromolar zinc-binding domain on the NMDA receptor subunit NR2B.

24 September 2018

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Mapping the binding site of the neuroprotectant ifenprodil on NMDA receptors.

24 September 2018

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Site-specific incorporation of fluorescent probes into protein: hexahistidine-tag-mediated fluorescent labeling with (Ni(2 ):nitrilotriacetic Acid (n)-fluorochrome conjugates

24 September 2018

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Molecular organization of a zinc binding n-terminal modulatory domain in a NMDA receptor subunit

24 September 2018

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Identification and mechanism of action of two histidine residues underlying high-affinity Zn2 inhibition of the NMDA receptor

24 September 2018

1 reference

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Phenylethanolamines inhibit NMDA receptors by enhancing proton inhibition

24 September 2018

1 reference

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A novel mechanism of activity-dependent NMDA receptor antagonism describes the effect of ifenprodil in rat cultured cortical neurones

24 September 2018

1 reference

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Rapid solution application methods

24 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26170175

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1085/JGP.201511422

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26170175 AND SRC:MED&resulttype=core&format=json

19 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26170175 AND SRC:MED&resulttype=core&format=json

19 February 2020

PubMed publication ID

26170175

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26170175 AND SRC:MED&resulttype=core&format=json