Genome-wide Profiling Reveals Remarkable Parallels Between Insertion Site Selection Properties of the MLV Retrovirus and the piggyBac Transposon in Primary Human CD4( ) T Cells. (Q35891332)

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scientific article published on 12 January 2016

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English	Genome-wide Profiling Reveals Remarkable Parallels Between Insertion Site Selection Properties of the MLV Retrovirus and the piggyBac Transposon in Primary Human CD4( ) T Cells.	scientific article published on 12 January 2016

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4 March 2020

Genome-wide Profiling Reveals Remarkable Parallels Between Insertion Site Selection Properties of the MLV Retrovirus and the piggyBac Transposon in Primary Human CD4( ) T Cells (English)

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Zsuzsanna Izsvák

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Zoltán Ivics

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Ismahen Ammar

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Saumyashree Gupta

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Csaba Miskey

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Wei Chen

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Wolfgang Uckert

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Thomas F Schulz

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Andreas Gogol-Döring

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12 January 2016

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Molecular Therapy

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592-606

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Structural basis for retroviral integration into nucleosomes.

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Chromatin landscapes of retroviral and transposon integration profiles

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MLV integration site selection is driven by strong enhancers and active promoters

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Integration profiling of gene function with dense maps of transposon integration

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Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome.

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BET proteins promote efficient murine leukemia virus integration at transcription start sites

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Determinants of nucleosome positioning

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The piggyBac transposon displays local and distant reintegration preferences and can cause mutations at noncanonical integration sites

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The Mu transpososome structure sheds light on DDE recombinase evolution

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A resurrected mammalian hAT transposable element and a closely related insect element are highly active in human cell culture

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Bromodomain-containing protein 4 (BRD4) regulates RNA polymerase II serine 2 phosphorylation in human CD4 T cells

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Nonviral gene delivery with the sleeping beauty transposon system.

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Manipulating piggyBac Transposon Chromosomal Integration Site Selection in Human Cells

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CpG islands and the regulation of transcription

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Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages

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The Drosophila Gene Disruption Project: Progress Using Transposons With Distinctive Site Specificities

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Comparative genomic integration profiling of Sleeping Beauty transposons mobilized with high efficacy from integrase-defective lentiviral vectors in primary human cells

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Retroviral vector integration deregulates gene expression but has no consequence on the biology and function of transplanted T cells.

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Brd2/RING3 interacts with a chromatin-binding domain in the Kaposi's Sarcoma-associated herpesvirus latency-associated nuclear antigen 1 (LANA-1) that is required for multiple functions of LANA-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786924

11 July 2018

Interaction of bovine papillomavirus E2 protein with Brd4 stabilizes its association with chromatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786924

11 July 2018

The mitotic chromosome binding activity of the papillomavirus E2 protein correlates with interaction with the cellular chromosomal protein, Brd4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786924

11 July 2018

High-resolution genome-wide mapping of transposon integration in mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786924

11 July 2018

Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786924

11 July 2018

Chance or necessity? Insertional mutagenesis in gene therapy and its consequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786924

11 July 2018

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786924

11 July 2018

Transcription start regions in the human genome are favored targets for MLV integration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786924

11 July 2018

HIV-1 integration in the human genome favors active genes and local hotspots

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786924

11 July 2018

Involvement of a bifunctional, paired-like DNA-binding domain and a transpositional enhancer in Sleeping Beauty transposition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786924

11 July 2018

Organization and dynamics of the Mu transpososome: recombination by communication between two active sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786924

11 July 2018

The same two monomers within a MuA tetramer provide the DDE domains for the strand cleavage and strand transfer steps of transposition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786924

11 July 2018

Structural aspects of a higher order nucleoprotein complex: induction of an altered DNA structure at the Mu-host junction of the Mu type 1 transpososome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786924

11 July 2018

Chromosomal mobilization and reintegration of Sleeping Beauty and PiggyBac transposons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786924

24 September 2018

Resistance of mature T cells to oncogene transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786924

24 September 2018

High-resolution insertion-site analysis by linear amplification-mediated PCR (LAM-PCR).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786924

24 September 2018

Target-site preferences of Sleeping Beauty transposons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786924

24 September 2018

Common physical properties of DNA affecting target site selection of sleeping beauty and other Tc1/mariner transposable elements.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786924

24 September 2018

Safe harbours for the integration of new DNA in the human genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786924

6 December 2018

Identifiers

10.1038/MT.2016.11

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26755332 AND SRC:MED&resulttype=core&format=json

4 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26755332 AND SRC:MED&resulttype=core&format=json

4 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26755332 AND SRC:MED&resulttype=core&format=json

4 March 2020

ResearchGate publication ID

0 references

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