PTENless means more. (Q35870626)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15328005 AND SRC:MED&resulttype=core&format=json

1 January 2020

review article

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title

PTENless means more (English)

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1 January 2020

2

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1 January 2020

author name string

Bangyan Stiles

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15328005 AND SRC:MED&resulttype=core&format=json

1 January 2020

Shunyou Wang

3

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1 January 2020

Jing Jiao

4

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1 January 2020

Hong Wu

5

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1 January 2020

language of work or name

English

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publication date

1 September 2004

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15328005 AND SRC:MED&resulttype=core&format=json

1 January 2020

number of pages

10

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based on heuristic

inferred from page(s)

published in

Developmental Biology

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1 January 2020

volume

273

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1 January 2020

issue

2

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1 January 2020

page(s)

175-184

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Mutational spectra of PTEN/MMAC1 gene: a tumor suppressor with lipid phosphatase activity

1 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Deletion ofPTEN in a patient with Bannayan-Riley-Ruvalcaba syndrome suggests allelism with Cowden disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Phosphorylation of HDM2 by Akt.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Somatic mutation of PTEN in bladder carcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Igf1 gene disruption results in reduced brain size, CNS hypomyelination, and loss of hippocampal granule and striatal parvalbumin-containing neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

The Ptentative nature of mouse knockouts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Regulation of cell death protease caspase-9 by phosphorylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Inhibition of the Phosphoinositide 3-Kinase Pathway Induces a Senescence-like Arrest Mediated by p27Kip1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

PTEN, a unique tumor suppressor gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Interleukin-3-Induced Phosphorylation of BAD Through the Protein Kinase Akt

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Pten is essential for embryonic development and tumour suppression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

PTEN overexpression suppresses proliferation and differentiation and enhances apoptosis of the mouse mammary epithelium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Reduced PTEN expression in the pancreas overexpressing transforming growth factor-beta 1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Drosophila PTEN regulates cell growth and proliferation through PI3K-dependent and -independent pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Regulation of the insulin-like developmental pathway of Caenorhabditis elegans by a homolog of the PTEN tumor suppressor gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Expression of the PTEN tumour suppressor protein during human development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Insulin receptor-mediated organ overgrowth in Drosophila is not restricted by body size

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Shc and FAK differentially regulate cell motility and directionality modulated by PTEN.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Tumor suppressor PTEN mediates sensing of chemoattractant gradients.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Regulation of beta-catenin signaling in the Wnt pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Conditional loss of PTEN leads to testicular teratoma and enhances embryonic germ cell production

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Physiological functions of Pten in mouse tissues

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Lhermitte-Duclos disease as a component of Cowden's syndrome. Case report and review of the literature

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Direct control of the Forkhead transcription factor AFX by protein kinase B

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

mTor is required for hypertrophy of Pten-deficient neuronal soma in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

PTEN in neural precursor cells: regulation of migration, apoptosis, and proliferation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Genetic deletion of the Pten tumor suppressor gene promotes cell motility by activation of Rac1 and Cdc42 GTPases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Phosphorylation-dependent ubiquitylation and degradation of androgen receptor by Akt require Mdm2 E3 ligase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Cowden's disease. A possible new symptom complex with multiple system involvement

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Expression of LKB1 and PTEN tumor suppressor genes during mouse embryonic development.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Prostate intraepithelial neoplasia induced by prostate restricted Akt activation: the MPAKT model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Androgen receptor expression is regulated by the phosphoinositide 3-kinase/Akt pathway in normal and tumoral epithelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Germline PTEN mutations in Cowden syndrome-like families.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

PTEN mutation spectrum and genotype-phenotype correlations in Bannayan-Riley-Ruvalcaba syndrome suggest a single entity with Cowden syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

The insulin-like growth factor 1 receptor induces physiological heart growth via the phosphoinositide 3-kinase(p110alpha) pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

The PTEN tumor suppressor homolog in Caenorhabditis elegans regulates longevity and dauer formation in an insulin receptor-like signaling pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Mammalian target of rapamycin: a new molecular target for breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Akt/PTEN signaling mediates estrogen-dependent proliferation of primordial germ cells in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Deletion of an amino-terminal sequence beta-catenin in vivo and promotes hyperphosporylation of the adenomatous polyposis coli tumor suppressor protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

The lipid phosphatase activity of PTEN is critical for its tumor supressor function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Germline mutations in the PTEN/MMAC1 gene in patients with Cowden disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Role of the phosphatidylinositol 3-kinase/Akt and mTOR/P70S6-kinase pathways in the proliferation and apoptosis in multiple myeloma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

IGF-I is required for normal embryonic growth in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Regulation of cell migration by the C2 domain of the tumor suppressor PTEN.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Stem cells, cancer, and cancer stem cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Regulation of dauer larva development in Caenorhabditis elegans by daf-18, a homologue of the tumour suppressor PTEN

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Insulin-like growth factor-I inhibits transcriptional responses of transforming growth factor-beta by phosphatidylinositol 3-kinase/Akt-dependent suppression of the activation of Smad3 but not Smad2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Essential role of AKT-1/protein kinase B alpha in PTEN-controlled tumorigenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Regulation of nuclear translocation of forkhead transcription factor AFX by protein kinase B

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Negative regulation of the forkhead transcription factor FKHR by Akt.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKBalpha

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Stem and progenitor cells: origins, phenotypes, lineage commitments, and transdifferentiations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Insulin regulates the activity of forkhead transcription factor Hnf-3beta/Foxa-2 by Akt-mediated phosphorylation and nuclear/cytosolic localization.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008

HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YDBIO.2004.06.008