IRE1α-Dependent Decay of CReP/Ppp1r15b mRNA Increases Eukaryotic Initiation Factor 2α Phosphorylation and Suppresses Protein Synthesis (Q35868391)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26031337 AND SRC:MED&resulttype=core&format=json

16 February 2020

title

IRE1α-Dependent Decay of CReP/Ppp1r15b mRNA Increases Eukaryotic Initiation Factor 2α Phosphorylation and Suppresses Protein Synthesis (English)

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16 February 2020

5

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16 February 2020

author name string

Jae-Seon So

1

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16 February 2020

Sungyun Cho

2

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16 February 2020

Sang-Hyun Min

3

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16 February 2020

Scot R Kimball

4

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16 February 2020

language of work or name

English

0 references

publication date

1 June 2015

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Molecular and Cellular Biology

16 February 2020

published in

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16 February 2020

volume

35

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16 February 2020

issue

16

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16 February 2020

page(s)

2761-2770

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Getting RIDD of RNA: IRE1 in cell fate regulation

16 February 2020

cites work

1 reference

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The unfolded-protein-response sensor IRE-1α regulates the function of CD8α dendritic cells.

11 July 2018

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Endoplasmic reticulum stress sensing in the unfolded protein response

11 July 2018

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Silencing of lipid metabolism genes through IRE1α-mediated mRNA decay lowers plasma lipids in mice.

11 July 2018

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11 July 2018

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11 July 2018

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IRE1α activation protects mice against acetaminophen-induced hepatotoxicity

11 July 2018

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The unfolded protein response: integrating stress signals through the stress sensor IRE1α

11 July 2018

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Dual and opposing roles of the unfolded protein response regulated by IRE1alpha and XBP1 in proinsulin processing and insulin secretion

11 July 2018

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Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis

11 July 2018

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Both Transcriptional Regulation and Translational Control of ATF4 Are Central to the Integrated Stress Response

11 July 2018

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Identification of a consensus element recognized and cleaved by IRE1 alpha.

11 July 2018

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Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability

11 July 2018

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IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates.

11 July 2018

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Regulated Ire1-dependent decay of messenger RNAs in mammalian cells

11 July 2018

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Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2alpha) dephosphorylation in mammalian development

11 July 2018

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Regulation of hepatic lipogenesis by the transcription factor XBP1

11 July 2018

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XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks

11 July 2018

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Signal integration in the endoplasmic reticulum unfolded protein response

11 July 2018

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Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response.

11 July 2018

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Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha

11 July 2018

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11 July 2018

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A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress

11 July 2018

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XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation

11 July 2018

1 reference

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Inhibition of a constitutive translation initiation factor 2alpha phosphatase, CReP, promotes survival of stressed cells

11 July 2018

1 reference

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XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

11 July 2018

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Delineation of a negative feedback regulatory loop that controls protein translation during endoplasmic reticulum stress

11 July 2018

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The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas

11 July 2018

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Translational control is required for the unfolded protein response and in vivo glucose homeostasis

11 July 2018

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Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival

11 July 2018

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Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha

11 July 2018

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Regulated translation initiation controls stress-induced gene expression in mammalian cells

11 July 2018

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Tripartite management of unfolded proteins in the endoplasmic reticulum

11 July 2018

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Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

11 July 2018

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A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells

11 July 2018

1 reference

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Neuronal ER stress impedes myeloid-cell-induced vascular regeneration through IRE1α degradation of netrin-1.

11 July 2018

1 reference

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PERK is essential for neonatal skeletal development to regulate osteoblast proliferation and differentiation.

24 September 2018

1 reference

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PERK EIF2AK3 control of pancreatic beta cell differentiation and proliferation is required for postnatal glucose homeostasis.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508316

Initiation of protein synthesis in a cell-free system prepared from rat hepatocytes.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508316

GCN2 phosphorylation of eIF2alpha activates NF-kappaB in response to UV irradiation

24 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26031337

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.00215-15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26031337 AND SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26031337 AND SRC:MED&resulttype=core&format=json

16 February 2020

PubMed publication ID

26031337

1 reference