Apelin Enhances Brown Adipogenesis and Browning of White Adipocytes (Q35860844)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25931124 AND SRC:MED&resulttype=core&format=json

7 March 2020

title

Apelin Enhances Brown Adipogenesis and Browning of White Adipocytes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25931124 AND SRC:MED&resulttype=core&format=json

7 March 2020

1 reference

1 reference

Melvin Khee-Shing Leow

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25931124 AND SRC:MED&resulttype=core&format=json

7 March 2020

Peng Chen

7

1 reference

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7 March 2020

author name string

Aung Than

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25931124 AND SRC:MED&resulttype=core&format=json

7 March 2020

Hui Ling He

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25931124 AND SRC:MED&resulttype=core&format=json

7 March 2020

Si Hui Chua

3

1 reference

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7 March 2020

Dan Xu

4

1 reference

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7 March 2020

Lei Sun

5

1 reference

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7 March 2020

language of work or name

English

0 references

publication date

30 April 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25931124 AND SRC:MED&resulttype=core&format=json

7 March 2020

number of pages

13

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

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7 March 2020

volume

290

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25931124 AND SRC:MED&resulttype=core&format=json

7 March 2020

issue

23

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7 March 2020

page(s)

14679-14691

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25931124 AND SRC:MED&resulttype=core&format=json

Comparison of mitochondrial fluorescent dyes in stromal cells

7 March 2020

cites work

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MicroRNAs are required for the feature maintenance and differentiation of brown adipocytes.

11 July 2018

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PI3K/Akt is involved in brown adipogenesis mediated by growth differentiation factor-5 in association with activation of the Smad pathway.

11 July 2018

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Reduced UCP-1 content in in vitro differentiated beige/brite adipocytes derived from preadipocytes of human subcutaneous white adipose tissues in obesity

11 July 2018

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Irisin and FGF21 are cold-induced endocrine activators of brown fat function in humans

11 July 2018

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Hormone-induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure

11 July 2018

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Role of IL-6 in exercise training- and cold-induced UCP1 expression in subcutaneous white adipose tissue

11 July 2018

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Apelin attenuates oxidative stress in human adipocytes.

11 July 2018

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Adipose tissue browning and metabolic health

11 July 2018

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11 July 2018

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Pyroglutamyl apelin-13 identified as the major apelin isoform in human plasma

11 July 2018

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Cold acclimation recruits human brown fat and increases nonshivering thermogenesis.

11 July 2018

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Recruited brown adipose tissue as an antiobesity agent in humans

11 July 2018

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Understanding the brown adipocyte as a contributor to energy homeostasis

11 July 2018

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Control of adipogenesis by the autocrine interplays between angiotensin 1-7/Mas receptor and angiotensin II/AT1 receptor signaling pathways

11 July 2018

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Inflammation induced by RAW macrophages suppresses UCP1 mRNA induction via ERK activation in 10T1/2 adipocytes.

11 July 2018

1 reference

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Brown adipose tissue regulates glucose homeostasis and insulin sensitivity.

11 July 2018

1 reference

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Apelin inhibits adipogenesis and lipolysis through distinct molecular pathways.

11 July 2018

1 reference

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Mitochondrial structure, function and dynamics are temporally controlled by c-Myc

11 July 2018

1 reference

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The impact of aerobic exercise training on novel adipokines, apelin and ghrelin, in patients with type 2 diabetes

11 July 2018

1 reference

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FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis

11 July 2018

1 reference

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Brown adipose tissue oxidative metabolism contributes to energy expenditure during acute cold exposure in humans.

11 July 2018

1 reference

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Apelin secretion and expression of apelin receptors in 3T3-L1 adipocytes are differentially regulated by angiotensin type 1 and type 2 receptors.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505534

Programming human pluripotent stem cells into white and brown adipocytes.

11 July 2018

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A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505534

Apelin treatment increases complete Fatty Acid oxidation, mitochondrial oxidative capacity, and biogenesis in muscle of insulin-resistant mice.

11 July 2018

1 reference

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Apelin, diabetes, and obesity.

11 July 2018

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Current Methods of Adipogenic Differentiation of Mesenchymal Stem Cells

11 July 2018

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Apelin stimulates glucose uptake through the PI3K/Akt pathway and improves insulin resistance in 3T3-L1 adipocytes

11 July 2018

1 reference

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Altered fusion dynamics underlie unique morphological changes in mitochondria during hypoxia–reoxygenation stress

11 July 2018

1 reference

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Regulation of brown fat adipogenesis by protein tyrosine phosphatase 1B

11 July 2018

1 reference

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Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice

11 July 2018

1 reference

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The crosstalks between adipokines and catecholamines.

11 July 2018

1 reference

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Apelin decreases lipolysis via G(q), G(i), and AMPK-Dependent Mechanisms

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505534

International Union of Basic and Clinical Pharmacology. LXXIV. Apelin receptor nomenclature, distribution, pharmacology, and function

11 July 2018

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Vesicular storage, vesicle trafficking, and secretion of leptin and resistin: the similarities, differences, and interplays.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505534

Brown adipose tissue--a new role in humans?

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505534

Brown fat as a therapy for obesity and diabetes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505534

Adenosine 5'-monophosphate-activated protein kinase-mammalian target of rapamycin cross talk regulates brown adipocyte differentiation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505534

The autocrine and paracrine roles of adipokines.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505534

Apelin is necessary for the maintenance of insulin sensitivity

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505534

Identification and importance of brown adipose tissue in adult humans

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505534

Cold-activated brown adipose tissue in healthy men

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505534

Transcriptional control of brown adipocyte development and physiological function--of mice and men.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505534

The transcriptional co-activator PGC-1alpha up regulates apelin in human and mouse adipocytes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505534

Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505534

Adipose tissue macrophages, low grade inflammation and insulin resistance in human obesity.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505534

Transcriptional control of brown fat determination by PRDM16

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505534

Adipose tissue and adipokines--energy regulation from the human perspective.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505534

The apelin receptor is coupled to Gi1 or Gi2 protein and is differentially desensitized by apelin fragments.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505534

Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505534

Exercise training promotes expression of apelin and APJ of cardiovascular tissues in spontaneously hypertensive rats

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505534

PPARgamma in the control of brown adipocyte differentiation.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505534

Apelin, a newly identified adipokine up-regulated by insulin and obesity

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505534

Obesity, Metabolic Syndrome, and Cardiovascular Disease

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505534

Adipose-specific peroxisome proliferator-activated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505534

Tumor necrosis factor alpha mediates apoptosis of brown adipocytes and defective brown adipocyte function in obesity

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505534

Induction of uncoupling protein expression in brown and white adipose tissue by leptin

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505534

Immunohistochemical localization of leptin and uncoupling protein in white and brown adipose tissue

11 July 2018

1 reference

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Development of obesity in transgenic mice after genetic ablation of brown adipose tissue

11 July 2018

1 reference

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Effect of endurance training on skeletal muscle myokine expression in obese men: identification of apelin as a novel myokine

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505534

The apelinergic system: sexual dimorphism and tissue-specific modulations by obesity and insulin resistance in female mice

24 September 2018

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Increase in brown adipose tissue activity after weight loss in morbidly obese subjects.

24 September 2018

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Differentiation and characterization in primary culture of white adipose tissue brown adipocyte-like cells

24 September 2018

1 reference

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The PPARgamma agonist rosiglitazone enhances rat brown adipose tissue lipogenesis from glucose without altering glucose uptake

24 September 2018

1 reference

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Reduced Expression of FOXC2 and Brown Adipogenic Genes in Human Subjects with Insulin Resistance

24 September 2018

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Peripheral, but not central, administration of adiponectin reduces visceral adiposity and upregulates the expression of uncoupling protein in agouti yellow (Ay/a) obese mice

24 September 2018

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Understanding adipocyte differentiation

24 September 2018

1 reference

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TNF-alpha inhibits UCP-1 expression in brown adipocytes via ERKs. Opposite effect of p38MAPK

24 September 2018

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12 December 2020

Leptin and UCP1 genes are reciprocally regulated in brown adipose tissue

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12 December 2020

Peroxisome proliferator-activated receptors gamma and alpha mediate in vivo regulation of uncoupling protein (UCP-1, UCP-2, UCP-3) gene expression.

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12 December 2020

Apelin, an APJ receptor ligand, regulates body adiposity and favors the messenger ribonucleic acid expression of uncoupling proteins in mice

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12 December 2020

Identifiers

DOI

10.1074/JBC.M115.643817

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25931124 AND SRC:MED&resulttype=core&format=json

7 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25931124 AND SRC:MED&resulttype=core&format=json

7 March 2020

PubMed publication ID

25931124

1 reference