Historical review: a brief history and personal retrospective of seven-transmembrane receptors (Q35847116)

10 August 2017

title

Historical review: a brief history and personal retrospective of seven-transmembrane receptors (English)

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10 August 2017

main subject

transmembrane protein

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1

Robert J Lefkowitz

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10 August 2017

publication date

1 August 2004

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Trends in Pharmacological Sciences

10 August 2017

published in

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10 August 2017

volume

25

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10 August 2017

issue

8

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10 August 2017

page(s)

413-422

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beta-Arrestin: a protein that regulates beta-adrenergic receptor function

10 August 2017

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Light-dependent phosphorylation of rhodopsin: number of phosphorylation sites

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Model systems for the study of seven-transmembrane-segment receptors

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Expansion of the alpha 2-adrenergic receptor family: cloning and characterization of a human alpha 2-adrenergic receptor subtype, the gene for which is located on chromosome 2

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Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

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G protein-coupled receptor kinases

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Molecular cloning and expression of the cDNA for the hamster alpha 1-adrenergic receptor

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11 October 2022

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Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes

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beta-Arrestin scaffolding of the ERK cascade enhances cytosolic ERK activity but inhibits ERK-mediated transcription following angiotensin AT1a receptor stimulation

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Continued discovery of ligands for G protein-coupled receptors

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Cloning and expression of a human kidney cDNA for an alpha 2-adrenergic receptor subtype

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Light-dependent phosphorylation of rhodopsin by beta-adrenergic receptor kinase

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11 October 2022

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Phosphodiesterase activation by photoexcited rhodopsin is quenched when rhodopsin is phosphorylated and binds the intrinsic 48-kDa protein of rod outer segments

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11 October 2022

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Cloning of the gene and cDNA for mammalian beta-adrenergic receptor and homology with rhodopsin

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11 October 2022

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An intronless gene encoding a potential member of the family of receptors coupled to guanine nucleotide regulatory proteins

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11 October 2022

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Crystal structure of rhodopsin: A G protein-coupled receptor

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11 October 2022

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Antagonists with negative intrinsic activity at delta opioid receptors coupled to GTP-binding proteins

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11 October 2022

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Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

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11 October 2022

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Three-dimensional model of purple membrane obtained by electron microscopy

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11 October 2022

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G protein-coupled receptor interacting proteins: emerging roles in localization and signal transduction

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11 October 2022

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A family of receptors coupled to guanine nucleotide regulatory proteins

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11 October 2022

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Keeping G proteins at bay: a complex between G protein-coupled receptor kinase 2 and Gbetagamma

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11 October 2022

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G proteins: transducers of receptor-generated signals

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11 October 2022

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Beta-adrenergic receptor kinase: identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptor

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11 October 2022

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Primary and secondary structure of bovine retinal S antigen (48-kDa protein).

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11 October 2022

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The genomic clone G-21 which resembles a beta-adrenergic receptor sequence encodes the 5-HT1A receptor

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11 October 2022

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Defective lymphocyte chemotaxis in beta-arrestin2- and GRK6-deficient mice.

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The structure of bovine rhodopsin

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Nobel lecture in physiology or medicine--1988. Drugs from emasculated hormones: the principle of syntopic antagonism

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β-Arrestin1 Mediates Insulin-like Growth Factor 1 (IGF-1) Activation of Phosphatidylinositol 3-Kinase (PI3K) and Anti-apoptosis

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11 October 2022

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Cyclic GMP cascade of vision

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11 October 2022

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Reconstitution of beta-adrenergic receptors in lipid vesicles: affinity chromatography-purified receptors confer catecholamine responsiveness on a heterologous adenylate cyclase system

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11 October 2022

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Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.TIPS.2004.06.006

beta-arrestins regulate mitogenic signaling and clathrin-mediated endocytosis of the insulin-like growth factor I receptor

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.TIPS.2004.06.006

Functional architecture of the nicotinic acetylcholine receptor: a prototype of ligand-gated ion channels

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.TIPS.2004.06.006

Seven-transmembrane receptors

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.TIPS.2004.06.006

Molecular distinction between muscarinic acetylcholine receptor subtypes

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.TIPS.2004.06.006

Cloning of the cDNA for the human beta 1-adrenergic receptor

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.TIPS.2004.06.006

A novel multigene family may encode odorant receptors: a molecular basis for odor recognition

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.TIPS.2004.06.006

Dimerization: an emerging concept for G protein-coupled receptor ontogeny and function

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.TIPS.2004.06.006

The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.TIPS.2004.06.006

Beta-arrestin2 is critically involved in CXCR4-mediated chemotaxis, and this is mediated by its enhancement of p38 MAPK activation

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.TIPS.2004.06.006

Catecholamine-induced desensitization of turkey erythrocyte adenylate cyclase is associated with phosphorylation of the beta-adrenergic receptor

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.TIPS.2004.06.006

Structure of the m1 muscarinic acetylcholine receptor gene and its promoter

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.TIPS.2004.06.006

β1-adrenergic receptor polymorphisms confer differential function and predisposition to heart failure

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.TIPS.2004.06.006

Molecular cloning of the thyrotropin receptor

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.TIPS.2004.06.006

Multifaceted roles of beta-arrestins in the regulation of seven-membrane-spanning receptor trafficking and signalling

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.TIPS.2004.06.006

Arresting developments in heptahelical receptor signaling and regulation

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.TIPS.2004.06.006

Non-visual GRKs: are we seeing the whole picture?

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11 October 2022

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Historical review: Opioid receptors

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.TIPS.2004.06.006

G protein-coupled receptor kinases

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.TIPS.2004.06.006

Human dopamine D1 receptor encoded by an intronless gene on chromosome 5

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.TIPS.2004.06.006

Receptors and G proteins as primary components of transmembrane signal transduction. Part 1. G-protein-coupled receptors: structure and function.

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.TIPS.2004.06.006

Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.TIPS.2004.06.006

The 2.8 A crystal structure of visual arrestin: a model for arrestin's regulation

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.TIPS.2004.06.006

Mammalian .beta.2-adrenergic receptor: purification and characterization

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.TIPS.2004.06.006

Functional desensitization of the isolated beta-adrenergic receptor by the beta-adrenergic receptor kinase: potential role of an analog of the retinal protein arrestin (48-kDa protein)

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.TIPS.2004.06.006

Rhodopsin and bacteriorhodopsin: structure-function relationships

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.TIPS.2004.06.006

Cloning, sequencing, and expression of the gene coding for the human platelet alpha 2-adrenergic receptor

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.TIPS.2004.06.006

Mutagenesis of the beta2-Adrenergic Receptor: How Structure Elucidates Function

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.TIPS.2004.06.006

The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.TIPS.2004.06.006

Adenyl cyclase as an adrenergic receptor

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.TIPS.2004.06.006

Identifiers

DOI

10.1016/J.TIPS.2004.06.006

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10 August 2017

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