Oncogenic gamma-herpesviruses: comparison of viral proteins involved in tumorigenesis (Q35841060)

10 August 2017

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title

Oncogenic gamma-herpesviruses: comparison of viral proteins involved in tumorigenesis (English)

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10 August 2017

1

Blossom Damania

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10 August 2017

language of work or name

English

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publication date

1 August 2004

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Nature Reviews Microbiology

10 August 2017

published in

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10 August 2017

volume

2

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10 August 2017

issue

8

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10 August 2017

page(s)

656-668

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VIRUS PARTICLES IN CULTURED LYMPHOBLASTS FROM BURKITT'S LYMPHOMA

10 August 2017

cites work

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An EBV membrane protein expressed in immortalized lymphocytes transforms established rodent cells.

21 January 2018

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Epstein-Barr virus latent membrane protein inhibits human epithelial cell differentiation

21 January 2018

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Mimicry of CD40 signals by Epstein-Barr virus LMP1 in B lymphocyte responses

21 January 2018

1 reference

Latent membrane protein 1 of Epstein-Barr virus mimics a constitutively active receptor molecule.

21 January 2018

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Epstein-Barr virus-mediated B-cell proliferation is dependent upon latent membrane protein 1, which simulates an activated CD40 receptor

21 January 2018

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The Epstein-Barr virus oncoprotein latent membrane protein 1 engages the tumor necrosis factor receptor-associated proteins TRADD and receptor-interacting protein (RIP) but does not induce apoptosis or require RIP for NF-kappaB activation

21 January 2018

1 reference

Epstein-Barr virus latent membrane protein 1 (LMP1) activates the phosphatidylinositol 3-kinase/Akt pathway to promote cell survival and induce actin filament remodeling

21 January 2018

1 reference

Activation of the cJun N-terminal kinase (JNK) pathway by the Epstein-Barr virus-encoded latent membrane protein 1 (LMP1).

21 January 2018

1 reference

Epstein-Barr virus latent-infection membrane proteins are palmitoylated and raft-associated: protein 1 binds to the cytoskeleton through TNF receptor cytoplasmic factors

21 January 2018

1 reference

Latent infection membrane protein transmembrane FWLY is critical for intermolecular interaction, raft localization, and signaling

21 January 2018

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Induction of cyclooxygenase-2 by Epstein-Barr virus latent membrane protein 1 is involved in vascular endothelial growth factor production in nasopharyngeal carcinoma cells

21 January 2018

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The expression of matrix metalloproteinase 9 is enhanced by Epstein–Barr virus latent membrane protein 1

21 January 2018

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The NPC derived C15 LMP1 protein confers enhanced activation of NF-kappa B and induction of the EGFR in epithelial cells.

21 January 2018

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Deregulation of cell growth by the K1 gene of Karposi's sarcoma-associated herpesvirus

21 January 2018

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Tumorigenesis and aberrant signaling in transgenic mice expressing the human herpesvirus-8 K1 gene

21 January 2018

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The Structure and Coding Organization of the Genomic Termini of Kaposi's Sarcoma-Associated Herpesvirus (Human Herpesvirus 8)

21 January 2018

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Deregulated signal transduction by the K1 gene product of Kaposi's sarcoma-associated herpesvirus

21 January 2018

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Identification of an immunoreceptor tyrosine-based activation motif of K1 transforming protein of Kaposi's sarcoma-associated herpesvirus

21 January 2018

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The K1 protein of Kaposi's sarcoma-associated herpesvirus activates the Akt signaling pathway

21 January 2018

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Structural analysis of the Kaposi's sarcoma-associated herpesvirus K1 protein

21 January 2018

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Identification of the novel K15 gene at the rightmost end of the Kaposi's sarcoma-associated herpesvirus genome

21 January 2018

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Association of the viral oncoprotein STP-C488 with cellular ras.

21 January 2018

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The Immunoreceptor Tyrosine-Based Activation Motif of Epstein–Barr Virus LMP2A Is Essential for Blocking BCR-Mediated Signal Transduction

21 January 2018

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Epstein-Barr virus coopts lipid rafts to block the signaling and antigen transport functions of the BCR.

21 January 2018

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Latent membrane protein 2A inhibits transforming growth factor-beta 1-induced apoptosis through the phosphatidylinositol 3-kinase/Akt pathway

21 January 2018

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Epstein-Barr virus LMP2A drives B cell development and survival in the absence of normal B cell receptor signals

21 January 2018

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Epstein-Barr virus LMP2A transforms epithelial cells, inhibits cell differentiation, and activates Akt.

21 January 2018

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Epstein-Barr virus latent membrane protein 2A activates beta-catenin signaling in epithelial cells.

21 January 2018

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Activation of mitogen-activated protein kinase and NF-kappaB pathways by a Kaposi's sarcoma-associated herpesvirus K15 membrane protein

21 January 2018

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The product of the Herpesvirus saimiri open reading frame 1 (tip) interacts with T cell-specific kinase p56lck in transformed cells

21 January 2018

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Identification of Lck-binding elements in tip of herpesvirus saimiri

21 January 2018

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The herpesvirus saimiri tip484 and tip488 proteins both stimulate lck tyrosine protein kinase activity in vivo and in vitro

21 January 2018

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Herpesvirus saimiri Tip gene causes T-cell lymphomas in transgenic mice

21 January 2018

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Epstein-Barr virus nuclear protein 2 interacts with p300, CBP, and PCAF histone acetyltransferases in activation of the LMP1 promoter

21 January 2018

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Genetic analysis of immortalizing functions of Epstein-Barr virus in human B lymphocytes

21 January 2018

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Biochemical characterization of Epstein-Barr virus nuclear antigen 3A and 3C proteins

21 January 2018

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The Epstein-Barr virus determined nuclear antigens EBNA-3A, -3B, and -3C repress EBNA-2-mediated transactivation of the viral terminal protein 1 gene promoter

21 January 2018

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Signaling by human herpesvirus 8 kaposin A through direct membrane recruitment of cytohesin-1.

21 January 2018

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Characterization of the human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus) oncogene, kaposin (ORF K12).

21 January 2018

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Characterization of a chemokine receptor-related gene in human herpesvirus 8 and its expression in Kaposi's sarcoma

21 January 2018

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Patterns of gene expression and a transactivation function exhibited by the vGCR (ORF74) chemokine receptor protein of Kaposi's sarcoma-associated herpesvirus

21 January 2018

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Human herpesvirus KSHV encodes a constitutively active G-protein-coupled receptor linked to cell proliferation

21 January 2018

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Human interferon-gamma-inducible protein 10 (IP-10) inhibits constitutive signaling of Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor

21 January 2018

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The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor has broad signaling effects in primary effusion lymphoma cells

21 January 2018

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Kaposi's sarcoma associated herpesvirus G protein-coupled receptor immortalizes human endothelial cells by activation of the VEGF receptor-2/ KDR.

21 January 2018

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G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator

21 January 2018

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Activation of NF-kappaB by the human herpesvirus 8 chemokine receptor ORF74: evidence for a paracrine model of Kaposi's sarcoma pathogenesis

21 January 2018

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Transgenic expression of the chemokine receptor encoded by human herpesvirus 8 induces an angioproliferative disease resembling Kaposi's sarcoma

21 January 2018

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Kaposi's sarcoma-like tumors in a human herpesvirus 8 ORF74 transgenic mouse

21 January 2018

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The EBV nuclear antigen 1 (EBNA1) enhances B cell immortalization several thousandfold

21 January 2018

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Enhanced malignant progression of nasopharyngeal carcinoma cells mediated by the expression of Epstein-Barr nuclear antigen 1 in vivo

21 January 2018

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bcl-xL and RAG genes are induced and the response to IL-2 enhanced in EmuEBNA-1 transgenic mouse lymphocytes.

21 January 2018

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Epstein-Barr virus nuclear antigen 1 (EBNA1) induced cytotoxicity in epithelial cells is associated with EBNA1 degradation and processing

21 January 2018

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Inhibition of antigen processing by the internal repeat region of the Epstein-Barr virus nuclear antigen-1.

21 January 2018

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Inhibition of ubiquitin/proteasome-dependent protein degradation by the Gly-Ala repeat domain of the Epstein-Barr virus nuclear antigen 1.

21 January 2018

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Charting latency transcripts in Kaposi's sarcoma-associated herpesvirus by whole-genome real-time quantitative PCR

21 January 2018

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Efficient persistence of extrachromosomal KSHV DNA mediated by latency-associated nuclear antigen

21 January 2018

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The Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen binds to specific sequences at the left end of the viral genome through its carboxy-terminus

21 January 2018

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The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus permits replication of terminal repeat-containing plasmids.

21 January 2018

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Latency-associated nuclear antigen (LANA) cooperatively binds to two sites within the terminal repeat, and both sites contribute to the ability of LANA to suppress transcription and to facilitate DNA replication

21 January 2018

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p53 inhibition by the LANA protein of KSHV protects against cell death

21 January 2018

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The latent nuclear antigen of Kaposi sarcoma-associated herpesvirus targets the retinoblastoma-E2F pathway and with the oncogene Hras transforms primary rat cells

21 January 2018

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A novel viral mechanism for dysregulation of beta-catenin in Kaposi's sarcoma-associated herpesvirus latency.

21 January 2018

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The Latency-Associated Nuclear Antigen Homolog of Herpesvirus Saimiri Inhibits Lytic Virus Replication

21 January 2018

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The herpesvirus saimiri ORF73 gene product interacts with host-cell mitotic chromosomes and self-associates via its C terminus.

21 January 2018

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ORF73 of Herpesvirus Saimiri Strain C488 Tethers the Viral Genome to Metaphase Chromosomes and Binds to cis -Acting DNA Sequences in the Terminal Repeats

21 January 2018

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The Herpesvirus Saimiri open reading frame 73 gene product interacts with the cellular protein p32.

21 January 2018

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Kaposi's sarcoma-associated herpesvirus-encoded latency-associated nuclear antigen inhibits lytic replication by targeting Rta: a potential mechanism for virus-mediated control of latency

21 January 2018

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Viral interleukin 10 is critical for the induction of B cell growth transformation by Epstein-Barr virus

21 January 2018

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Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression

21 January 2018

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High level expression and purification of the Epstein-Barr virus encoded cytokine viral interleukin 10: efficient removal of endotoxin

21 January 2018

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Viral interleukin 10 (IL-10), the human herpes virus 4 cellular IL-10 homologue, induces local anergy to allogeneic and syngeneic tumors

21 January 2018

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Molecular mimicry of human cytokine and cytokine response pathway genes by KSHV.

21 January 2018

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Kaposi's sarcoma-associated human herpesvirus-8 encodes homologues of macrophage inflammatory protein-1 and interleukin-6.

21 January 2018

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Human herpesvirus 8-encoded interleukin-6 homologue (viral IL-6) induces endogenous human IL-6 secretion

21 January 2018

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Viral IL-6-induced cell proliferation and immune evasion of interferon activity

21 January 2018

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A Kaposi's sarcoma-associated herpesvirus-encoded cytokine homolog (vIL-6) activates signaling through the shared gp130 receptor subunit

21 January 2018

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Differential viral protein expression in Kaposi's sarcoma-associated herpesvirus-infected diseases: Kaposi's sarcoma, primary effusion lymphoma, and multicentric Castleman's disease.

21 January 2018

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Angiogenic and HIV-inhibitory functions of KSHV-encoded chemokines

21 January 2018

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Kaposi's sarcoma-associated herpesvirus (KSHV)-encoded vMIP-I and vMIP-II induce signal transduction and chemotaxis in monocytic cells

21 January 2018

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Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor

21 January 2018

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Herpesvirus saimiri encodes homologues of G protein-coupled receptors and cyclins

21 January 2018

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The apoptotic v-cyclin-CDK6 complex phosphorylates and inactivates Bcl-2.

21 January 2018

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Stable suppression of tumorigenicity by virus-mediated RNA interference

21 January 2018

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21 January 2018

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Independence of herpesvirus-induced T cell lymphoma from viral cyclin D homologue

21 January 2018

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Characterization of the herpesvirus saimiri ORF73 gene product

21 January 2018

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Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma

21 January 2018

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Tumour induction with DNA of oncogenic primate herpesviruses

31 March 2020

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Epstein-Barr virus latent membrane protein 1 is essential for B-lymphocyte growth transformation

31 March 2020

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A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor

31 March 2020

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The Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) K1 protein induces expression of angiogenic and invasion factors

31 March 2020

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Identification of transforming genes of subgroup A and C strains of Herpesvirus saimiri

31 March 2020

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An integral membrane protein (LMP2) blocks reactivation of Epstein-Barr virus from latency following surface immunoglobulin crosslinking

31 March 2020

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The Epstein-Barr virus nuclear antigen 2 transactivator is directed to response elements by the J kappa recombination signal binding protein

31 March 2020

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Epstein-Barr virus nuclear protein 2 is a key determinant of lymphocyte transformation

31 March 2020

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Chemokines activate Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor in mammalian cells in culture

31 March 2020

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Kaposi's sarcoma-associated herpesvirus (KSHV) chemokine vMIP-II and human SDF-1alpha inhibit signaling by KSHV G protein-coupled receptor

31 March 2020

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Endothelial infection with KSHV genes in vivo reveals that vGPCR initiates Kaposi's sarcomagenesis and can promote the tumorigenic potential of viral latent genes

31 March 2020

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The oncogenic potential of Kaposi's sarcoma-associated herpesvirus cyclin is exposed by p53 loss in vitro and in vivo

31 March 2020

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Role of the TRAF binding site and NF-kappaB activation in Epstein-Barr virus latent membrane protein 1-induced cell gene expression

31 March 2020

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7 January 2021

Herpesvirus saimiri strain variability

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7 January 2021

Deletion mutants of herpesvirus saimiri define an open reading frame necessary for transformation

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7 January 2021

Role of cellular tumor necrosis factor receptor-associated factors in NF-kappaB activation and lymphocyte transformation by herpesvirus Saimiri STP.

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7 January 2021

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7 January 2021

The last seven transmembrane and carboxy-terminal cytoplasmic domains of Epstein-Barr virus latent membrane protein 2 (LMP2) are dispensable for lymphocyte infection and growth transformation in vitro.

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7 January 2021

Identification of a spliced gene from Kaposi's sarcoma-associated herpesvirus encoding a protein with similarities to latent membrane proteins 1 and 2A of Epstein-Barr virus

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7 January 2021

Downregulation of Lck-mediated signal transduction by tip of herpesvirus saimiri

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7 January 2021

Enhanced downregulation of Lck-mediated signal transduction by a Y114 mutation of herpesvirus Saimiri tip

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7 January 2021

Non-immortalizing P3J-HR-1 Epstein-Barr virus: a deletion mutant of its transforming parent, Jijoye

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7 January 2021

Cellular tropism and viral interleukin-6 expression distinguish human herpesvirus 8 involvement in Kaposi's sarcoma, primary effusion lymphoma, and multicentric Castleman's disease

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7 January 2021

A complex translational program generates multiple novel proteins from the latently expressed kaposin (K12) locus of Kaposi's sarcoma-associated herpesvirus.

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7 January 2021

Human herpesvirus 8 encodes a homolog of interleukin-6.

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7 January 2021

Identifiers

DOI

10.1038/NRMICRO958

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Dimensions Publication ID

10 August 2017

1037056236

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