Mitochondrial function, inflammation, fat and bone in HIV lipoatrophy: randomized study of uridine supplementation or switch to tenofovir. (Q35827917)

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21 January 2020

title

Mitochondrial function, inflammation, fat and bone in HIV lipoatrophy: randomized study of uridine supplementation or switch to tenofovir (English)

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21 January 2020

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8

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Grace A McComsey

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21 January 2020

author name string

MaryAnn O'Riordan

2

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Julia Choi

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Daniel Libutti

4

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David Rowe

5

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Norma Storer

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Danielle Harrill

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21 January 2020

publication date

13 October 2011

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21 January 2020

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volume

17

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issue

2

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page(s)

347-353

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Bone mineral density and fractures in antiretroviral-naive persons randomized to receive abacavir-lamivudine or tenofovir disoproxil fumarate-emtricitabine along with efavirenz or atazanavir-ritonavir: Aids Clinical Trials Group A5224s, a substudy o

21 January 2020

cites work

1 reference

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Uridine supplementation in the treatment of HIV lipoatrophy: results of ACTG 5229

11 July 2018

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Tenofovir use is associated with an increase in serum alkaline phosphatase in the Swiss HIV Cohort Study.

11 July 2018

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Mitochondrial RNA and DNA alterations in HIV lipoatrophy are linked to antiretroviral therapy and not to HIV infection

11 July 2018

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Changes in metabolic toxicity after switching from stavudine/didanosine to tenofovir/lamivudine--a Staccato trial substudy

11 July 2018

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Pyrimidine nucleoside depletion sensitizes to the mitochondrial hepatotoxicity of the reverse transcriptase inhibitor stavudine

11 July 2018

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Reversibility of lipoatrophy in HIV-infected patients 2 years after switching from a thymidine analogue to abacavir: the MITOX Extension Study

11 July 2018

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Changes in bone mineral density with age in men and women: a longitudinal study

11 July 2018

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Symmetrical In Vivo Transcription of Mitochondrial DNA in HeLa Cells

11 July 2018

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A randomized comparative trial of continued zidovudine/lamivudine or replacement with tenofovir disoproxil fumarate/emtricitabine in efavirenz-treated HIV-1-infected individuals.

11 July 2018

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Mitochondrial function, morphology and metabolic parameters improve after switching from stavudine to a tenofovir-containing regimen

24 September 2018

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Improvements in subcutaneous fat, lipid profile, and parameters of mitochondrial toxicity in patients with peripheral lipoatrophy when stavudine is switched to tenofovir (LIPOTEST study).

24 September 2018

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The impact of reducing stavudine dose versus switching to tenofovir on plasma lipids, body composition and mitochondrial function in HIV-infected patients

24 September 2018

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Anti-inflammatory effects of exogenous uridine in an animal model of lung inflammation

24 September 2018

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Uridine supplementation for the treatment of antiretroviral therapy-associated lipoatrophy: a randomized, double-blind, placebo-controlled trial.

24 September 2018

1 reference

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Uridine abrogates the adverse effects of antiretroviral pyrimidine analogues on adipose cell functions.

24 September 2018

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Role of mitochondria in HIV lipoatrophy: insight into pathogenesis and potential therapies

24 September 2018

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Uridine pharmacokinetics of mitocnol, a sugar cane extract

24 September 2018

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Efficacy and safety of tenofovir DF vs stavudine in combination therapy in antiretroviral-naive patients: a 3-year randomized trial

24 September 2018

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Improvement in lipoatrophy associated with highly active antiretroviral therapy in human immunodeficiency virus-infected patients switched from stavudine to abacavir or zidovudine: the results of the TARHEEL study

24 September 2018

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Uridine abrogates mitochondrial toxicity related to nucleoside analogue reverse transcriptase inhibitors in HepG2 cells

24 September 2018

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Mitochondrial DNA depletion and morphologic changes in adipocytes associated with nucleoside reverse transcriptase inhibitor therapy

24 September 2018

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Uridine supplementation antagonizes zalcitabine-induced microvesicular steatohepatitis in mice

24 September 2018

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A randomized comparative trial of tenofovir DF or abacavir as replacement for a thymidine analogue in persons with lipoatrophy

22 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302940

Evidence of nucleoside analogue reverse transcriptase inhibitor--associated genetic and structural defects of mitochondria in adipose tissue of HIV-infected patients

6 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22293126

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3851/IMP1928

1 reference

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21 January 2020

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21 January 2020

PubMed publication ID

22293126

1 reference

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