Conserved Amblyomma americanum tick Serpin19, an inhibitor of blood clotting factors Xa and XIa, trypsin and plasmin, has anti-haemostatic functions. (Q35812375)

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scientific article published on 5 May 2015

Language	Label	Description	Also known as
English	Conserved Amblyomma americanum tick Serpin19, an inhibitor of blood clotting factors Xa and XIa, trypsin and plasmin, has anti-haemostatic functions.	scientific article published on 5 May 2015

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scholarly article

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7 March 2020

Conserved Amblyomma americanum tick Serpin19, an inhibitor of blood clotting factors Xa and XIa, trypsin and plasmin, has anti-haemostatic functions (English)

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7 March 2020

Amblyomma americanum

object named as

Amblyomma americanum

1 reference

based on heuristic

inferred from title

2

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7 March 2020

Zeljko Radulović

3

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7 March 2020

Itabajara da Silva Vaz Junior

7

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7 March 2020

Carlos Termignoni

9

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7 March 2020

author name string

Tae Kwon Kim

1

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7 March 2020

Lauren Lewis

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7 March 2020

Mariam Bakshi

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7 March 2020

Creston Hill

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7 March 2020

Carlos Logullo

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7 March 2020

Albert Mulenga

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7 March 2020

publication date

5 May 2015

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7 March 2020

International Journal for Parasitology

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7 March 2020

45

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7 March 2020

9-10

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7 March 2020

613-627

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7 March 2020

Amblyomma americanum tick calreticulin binds C1q but does not inhibit activation of the classical complement cascade

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Bioinformatic analyses of male and female Amblyomma americanum tick expressed serine protease inhibitors (serpins).

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Comparative Protein Structure Modeling Using MODELLER

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Amblyomma americanum tick saliva serine protease inhibitor 6 is a cross-class inhibitor of serine proteases and papain-like cysteine proteases that delays plasma clotting and inhibits platelet aggregation

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Validation of internal reference genes for real-time quantitative polymerase chain reaction studies in the tick, Ixodes scapularis (Acari: Ixodidae).

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The serine protease plasmin triggers expression of the CC-chemokine ligand 20 in dendritic cells via Akt/NF-κB-dependent pathways.

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The quest for a universal vaccine against ticks: cross-immunity insights.

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Differential recognition by tick-resistant cattle of the recombinantly expressed Rhipicephalus microplus serine protease inhibitor-3 (RMS-3).

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The sialotranscriptome of Antricola delacruzi female ticks is compatible with non-hematophagous behavior and an alternative source of food

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A deep insight into the sialotranscriptome of the gulf coast tick, Amblyomma maculatum

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Serpin-glycosaminoglycan interactions.

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An insight into the sialotranscriptome and proteome of the coarse bontlegged tick, Hyalomma marginatum rufipes

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Spn1 Regulates the GNBP3-Dependent Toll Signaling Pathway in Drosophila melanogaster

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A further insight into the sialome of the tropical bont tick, Amblyomma variegatum

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Amblyomma americanum (L.) (Acari: Ixodidae) tick salivary gland serine protease inhibitor (serpin) 6 is secreted into tick saliva during tick feeding

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Serpin structure, mechanism, and function

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Proteases in blood clotting

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Exploring the sialome of the tick Ixodes scapularis

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Isolation of Ixodes ricinus salivary gland mRNA encoding factors induced during blood feeding

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Activation of protease-activated receptor (PAR)-1, PAR-2, and PAR-4 stimulates IL-6, IL-8, and prostaglandin E2 release from human respiratory epithelial cells

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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Tick-Encoded serine proteinase inhibitors (serpins); potential target antigens for tick vaccine development

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

11 July 2018

The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

11 July 2018

A cell-based model of hemostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

11 July 2018

Borrelia lonestari infection after a bite by an Amblyomma americanum tick

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

11 July 2018

Boophilus microplus anticoagulant protein: an antithrombin inhibitor isolated from the cattle tick saliva.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

11 July 2018

Phylogeny of the serpin superfamily: implications of patterns of amino acid conservation for structure and function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

11 July 2018

Structure of a serpin-protease complex shows inhibition by deformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

11 July 2018

Prevalence of Ehrlichia ewingii in Amblyomma americanum in North Carolina

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

11 July 2018

The plasminogen (fibrinolytic) system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

11 July 2018

Serine proteinase inhibitors in arthropod immunity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

11 July 2018

Mast cell chymase and tryptase during tissue turnover: analysis on in vitro mitogenesis of fibroblasts and keratinocytes and alterations in cutaneous scars

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

11 July 2018

Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

11 July 2018

Protection against Boophilus annulatus infestations in cattle vaccinated with the B. microplus Bm86-containing vaccine Gavac. off.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

11 July 2018

SWISS‐MODEL and the Swiss‐Pdb Viewer: An environment for comparative protein modeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

11 July 2018

New Types of Clotting Factors and Defense Molecules Found in Horseshoe Crab Hemolymph: Their Structures and Functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

11 July 2018

The cleaved peptide of the thrombin receptor is a strong platelet agonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

11 July 2018

Limulus intracellular coagulation inhibitor type 3. Purification, characterization, cDNA cloning, and tissue localization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

11 July 2018

VMD: visual molecular dynamics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

11 July 2018

Overview on fibrinolysis: plasminogen activation pathways on fibrin and cell surfaces

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

11 July 2018

Families of serine peptidases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

11 July 2018

Lyme disease-a tick-borne spirochetosis?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

11 July 2018

Cathepsin G is a strong platelet agonist released by neutrophils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

11 July 2018

Susceptibility of Amblyomma americanum to natural and experimental infections with Theileria cervi.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

11 July 2018

Population growth rates for Amblyomma americanum (Acari: Ixodidae) on Bos indicus, B. taurus and B. indicus x B. taurus cattle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

11 July 2018

Epidemiologic characteristics of human tularemia in the southwest-central states, 1981-1987.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

11 July 2018

The coagulation cascade: initiation, maintenance, and regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

11 July 2018

Stereochemical quality of protein structure coordinates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

11 July 2018

In vitro and in vivo functions of thrombin-treated platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

11 July 2018

Thrombin-induced platelet aggregation is mediated by a platelet plasma membrane-bound lectin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

11 July 2018

Plasmin induces in vivo monocyte recruitment through protease-activated receptor-1-, MEK/ERK-, and CCR2-mediated signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

24 September 2018

Reassessment of the potential economic impact of cattle parasites in Brazil

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

24 September 2018

A family of serine protease inhibitors (serpins) in the cattle tick Rhipicephalus (Boophilus) microplus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

24 September 2018

Isolation and characterization of two novel serpins from the tick Rhipicephalus haemaphysaloides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

24 September 2018

Immunization of rabbits with recombinant serine protease inhibitor reduces the performance of adult female Rhipicephalus microplus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

24 September 2018

Plasmin triggers chemotaxis of monocyte-derived dendritic cells through an Akt2-dependent pathway and promotes a T-helper type-1 response.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

24 September 2018

Thrombin peptide TP508 stimulates rapid nitric oxide production in human endothelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

24 September 2018

Exosites mediate the anti-inflammatory effects of a multifunctional serpin from the saliva of the tick Ixodes ricinus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

24 September 2018

Effects of anti-tick cocktail vaccine against Rhipicephalus appendiculatus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

24 September 2018

Protective immunity against Ixodes ricinus induced by a salivary serpin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

24 September 2018

Anti-hemostatic effects of a serpin from the saliva of the tick Ixodes ricinus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

24 September 2018

Two serine protease inhibitors (serpins) that induce a bovine protective immune response against Rhipicephalus appendiculatus ticks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

24 September 2018

Tracing heme in a living cell: hemoglobin degradation and heme traffic in digest cells of the cattle tick Boophilus microplus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

24 September 2018

A serine protease inhibitor (serpin) from Haemaphysalis longicornis as an anti-tick vaccine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

24 September 2018

A serine proteinase inhibitor (serpin) from ixodid tick Haemaphysalis longicornis; cloning and preliminary assessment of its suitability as a candidate for a tick vaccine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

24 September 2018

Four serine proteinase inhibitors (serpin) from the brown ear tick, Rhiphicephalus appendiculatus; cDNA cloning and preliminary characterization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

24 September 2018

The increased bactericidal activity of a fatty acid-modified synthetic antimicrobial peptide of human cathepsin G correlates with its enhanced capacity to interact with model membranes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

24 September 2018

Protein Z-dependent regulation of coagulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

24 September 2018

Plasmin-induced expression of cytokines and tissue factor in human monocytes involves AP-1 and IKKbeta-mediated NF-kappaB activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

24 September 2018

Regulation of lymphocyte proliferation by eosinophils via chymotrypsin-like protease activity and adhesion molecule interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

24 September 2018

Glycosaminoglycan-protein interactions: definition of consensus sites in glycosaminoglycan binding proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

24 September 2018

A novel peptide motif for platelet fibrinogen receptor recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

24 September 2018

A thrombin inhibitor from the gut of Boophilus microplus ticks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490099

15 November 2018

Inhibition of integrin-mediated platelet aggregation, fibrinogen-binding, and interactions with extracellular matrix by nonpeptidic mimetics of Arg-Gly-Asp

1 reference

https://pubmed.ncbi.nlm.nih.gov/25957161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of cathepsin G-induced platelet activation by leukocyte elastase: consequence for the neutrophil-mediated platelet activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25957161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitors of chymotrypsin-like proteases inhibit eosinophil peroxidase release from activated human eosinophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/25957161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification of mast cell proteases from murine skin

1 reference

https://pubmed.ncbi.nlm.nih.gov/25957161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Injury thresholds and production loss functions for the lone star tick, Amblyomma americanum (Acari: Ixodidae), on pastured, preweaner beef cattle, Bos taurus

1 reference

https://pubmed.ncbi.nlm.nih.gov/25957161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of lipoprotein(a) on the binding of plasminogen to fibrin and its activation by fibrin-bound tissue-type plasminogen activator

1 reference

https://pubmed.ncbi.nlm.nih.gov/25957161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteinase 3. A neutrophil proteinase with activity on platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/25957161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amblyomma americanum: a potential vector of human ehrlichiosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25957161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Theileriosis in a white-tailed deer (Odocoileus virginianus) fawn

1 reference

https://pubmed.ncbi.nlm.nih.gov/25957161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ADP induces partial platelet aggregation without shape change and potentiates collagen-induced aggregation in the absence of Galphaq

1 reference

https://pubmed.ncbi.nlm.nih.gov/25957161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.IJPARA.2015.03.009

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25957161 AND SRC:MED&resulttype=core&format=json

7 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25957161 AND SRC:MED&resulttype=core&format=json

7 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25957161 AND SRC:MED&resulttype=core&format=json

7 March 2020

ResearchGate publication ID

0 references

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