Molecular mechanism of pharmacological activation of BK channels. (Q35807499)

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22 January 2020

title

Molecular mechanism of pharmacological activation of BK channels (English)

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22 January 2020

7

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22 January 2020

author name string

Guido Gessner

1

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22 January 2020

Yong-Mei Cui

2

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22 January 2020

Yuko Otani

3

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22 January 2020

Tomohiko Ohwada

4

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22 January 2020

Malle Soom

5

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22 January 2020

Toshinori Hoshi

6

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22 January 2020

language of work or name

English

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publication date

13 February 2012

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Proceedings of the National Academy of Sciences of the United States of America

22 January 2020

published in

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22 January 2020

volume

109

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22 January 2020

issue

9

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22 January 2020

page(s)

3552-3557

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Targeting BK (big potassium) channels in epilepsy

22 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

Ion sensing in the RCK1 domain of BK channels

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

BK channel activation: structural and functional insights

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

BK-type calcium-activated potassium channels: coupling of metal ions and voltage sensing

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

Structure of the gating ring from the human large-conductance Ca(2 )-gated K( ) channel

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

Structure of the human BK channel Ca2 -activation apparatus at 3.0 A resolution

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

A mutually exclusive alternative exon of slo1 codes for a neuronal BK channel with altered function.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

Convergent evolution of alternative splices at domain boundaries of the BK channel

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

BK channel modulators: a comprehensive overview

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

The RCK2 domain of the human BKCa channel is a calcium sensor

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

The small molecule NS11021 is a potent and specific activator of Ca2 -activated big-conductance K channels

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

High-conductance potassium channels of the SLO family

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

BKCa channels activating at resting potential without calcium in LNCaP prostate cancer cells.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

Role of charged residues in the S1-S4 voltage sensor of BK channels

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

Activation of the BK (SLO1) potassium channel by mallotoxin.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

Calcium-sensitive potassium channelopathy in human epilepsy and paroxysmal movement disorder

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

Linker-gating ring complex as passive spring and Ca(2 )-dependent machine for a voltage- and Ca(2 )-activated potassium channel

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

Coupling between voltage sensor activation, Ca2 binding and channel opening in large conductance (BK) potassium channels

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

New disguises for an old channel: MaxiK channel beta-subunits

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

Crystal structure and mechanism of a calcium-gated potassium channel

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

Protein kinases: tuners of the BKCa channel in smooth muscle.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

Targeting acute ischemic stroke with a calcium-sensitive opener of maxi-K potassium channels

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

Calcium sparks in smooth muscle

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

Modulation of the Ca(2 )-dependent K channel, hslo, by the substituted diphenylurea NS 1608, paxilline and internal Ca2 .

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

Selective activation of Ca(2 )-dependent K channels by novel benzimidazolone.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

Primary sequence and immunological characterization of beta-subunit of high conductance Ca(2 )-activated K channel from smooth muscle

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

A Component of Calcium-activated Potassium Channels Encoded by the Drosophila slo Locus

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

Novel oxime and oxime ether derivatives of 12,14-dichlorodehydroabietic acid: design, synthesis, and BK channel-opening activity

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

Voltage sensor of Kv1.2: structural basis of electromechanical coupling

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

A novel pyrrole derivative, NS-8, suppresses the rat micturition reflex by inhibiting afferent pelvic nerve activity

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

Dehydroabietic acid derivatives as a novel scaffold for large-conductance calcium-activated K channel openers.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

Multiple regulatory sites in large-conductance calcium-activated potassium channels.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

Mechanism of magnesium activation of calcium-activated potassium channels.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

An activator of calcium-dependent potassium channels isolated from a medicinal herb

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

Potentiation of large conductance KCa channels by niflumic, flufenamic, and mefenamic acids

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

NS 004--an activator of Ca(2 )-dependent K channels in cerebellar granule cells

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295268

The role of BK-type Ca2 -dependent K channels in spike broadening during repetitive firing in rat hippocampal pyramidal cells

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22331907

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1114321109

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22 January 2020

0 references

1 reference

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22 January 2020

PubMed publication ID

22331907

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22331907 AND SRC:MED&resulttype=core&format=json