St Johns wort increases expression of P-glycoprotein: implications for drug interactions (Q35804331)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11849198 AND SRC:MED&resulttype=core&format=json

7 December 2019

title

St Johns wort increases expression of P-glycoprotein: implications for drug interactions (English)

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7 December 2019

1

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7 December 2019

Paul Spiers

3

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7 December 2019

author name string

D Kelleher

2

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7 December 2019

M Barry

4

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7 December 2019

P Kavanagh

5

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D Back

6

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7 December 2019

F Mulcahy

7

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7 December 2019

J Feely

8

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7 December 2019

language of work or name

English

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publication date

1 January 2002

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British Journal of Clinical Pharmacology

7 December 2019

published in

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7 December 2019

volume

53

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7 December 2019

issue

1

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7 December 2019

page(s)

75-82

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Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin

7 December 2019

cites work

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St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor

11 July 2018

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Herb-drug interactions

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St John's wort for depression: a systematic review

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Inhibition of the CYP3A4-mediated metabolism and P-glycoprotein-mediated transport of the HIV-1 protease inhibitor saquinavir by grapefruit juice components

11 July 2018

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The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module

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The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin

11 July 2018

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A new PCR MIMIC strategy to quantify low mdr1 mRNA levels in drug resistant cell lines and AML blast samples

11 July 2018

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Biochemical, cellular, and pharmacological aspects of the multidrug transporter

11 July 2018

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Pharmacokinetics and potential interactions amongst antiretroviral agents used to treat patients with HIV infection

11 July 2018

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P-glycoprotein expression on normal and abnormally expanded natural killer cells and inhibition of P-glycoprotein function by cyclosporin A and its analogue, PSC833.

11 July 2018

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Modulation of MDR1 and CYP3A expression by dexamethasone: evidence for an inverse regulation in adrenals

11 July 2018

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Trends in alternative medicine use in the United States, 1990-1997: results of a follow-up national survey

11 July 2018

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SXR, a novel steroid and xenobiotic-sensing nuclear receptor

11 July 2018

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Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction

11 July 2018

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The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions

11 July 2018

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HIV-1 protease inhibitors are substrates for the MDR1 multidrug transporter.

11 July 2018

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An Orphan Nuclear Receptor Activated by Pregnanes Defines a Novel Steroid Signaling Pathway

11 July 2018

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Full blockade of intestinal P-glycoprotein and extensive inhibition of blood-brain barrier P-glycoprotein by oral treatment of mice with PSC833

11 July 2018

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St John's wort for depression--an overview and meta-analysis of randomised clinical trials

11 July 2018

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Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

11 July 2018

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11 July 2018

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21 January 2018

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12 December 2020

St John's Wort induces intestinal P-glycoprotein/MDR1 and intestinal and hepatic CYP3A4

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12 December 2020

Determination of hypericin in plasma by high-performance liquid chromatography

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12 December 2020

Ritonavir. Clinical pharmacokinetics and interactions with other anti-HIV agents

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Pharmacokinetic interaction of digoxin with an herbal extract from St John's wort (Hypericum perforatum)

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12 December 2020

Longitudinal assessment of a P-glycoprotein-mediated drug interaction of valspodar on digoxin

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Acute heart transplant rejection due to Saint John's wort

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St. John's wort: Hypericum perforatum

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12 December 2020

Effect of St. John's wort (Hypericum perforatum) on cytochrome P-450 2D6 and 3A4 activity in healthy volunteers

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12 December 2020

Significance of P-glycoprotein for the pharmacology and clinical use of HIV protease inhibitors

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12 December 2020

St John's Wort: effect on CYP3A4 activity

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12 December 2020

High-performance liquid chromatographic determination of the biologically active principle hypericin in phytotherapeutic vegetable extracts and alcoholic beverages

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12 December 2020

Methods to detect P-glycoprotein and implications for other drug resistance-associated proteins

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12 December 2020

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Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11849198 AND SRC:MED&resulttype=core&format=json

7 December 2019

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7 December 2019

PubMed publication ID

11849198

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11849198 AND SRC:MED&resulttype=core&format=json