Focal adhesion kinase-promoted tumor glucose metabolism is associated with a shift of mitochondrial respiration to glycolysis (Q35800385)

10 August 2017

Focal adhesion kinase-promoted tumor glucose metabolism is associated with a shift of mitochondrial respiration to glycolysis (English)

1 reference

10 August 2017

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26119934 AND SRC:MED&resulttype=core&format=json

14 June 2020

author name string

J Zhang

1

1 reference

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14 June 2020

Q Gao

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26119934 AND SRC:MED&resulttype=core&format=json

14 June 2020

Y Zhou

3

1 reference

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14 June 2020

U Dier

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26119934 AND SRC:MED&resulttype=core&format=json

14 June 2020

S N Hochwald

6

1 reference

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14 June 2020

language of work or name

English

0 references

publication date

29 June 2015

1 reference

10 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26119934 AND SRC:MED&resulttype=core&format=json

14 June 2020

volume

35

1 reference

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14 June 2020

issue

15

1 reference

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14 June 2020

page(s)

1926-1942

1 reference

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A small molecule FAK kinase inhibitor, GSK2256098, inhibits growth and survival of pancreatic ductal adenocarcinoma cells

14 June 2020

cites work

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Genome editing. The new frontier of genome engineering with CRISPR-Cas9

11 July 2018

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FOXM1 promotes the warburg effect and pancreatic cancer progression via transactivation of LDHA expression

11 July 2018

1 reference

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Metabolism addiction in pancreatic cancer

11 July 2018

1 reference

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Monocarboxylate transporter 4 facilitates cell proliferation and migration and is associated with poor prognosis in oral squamous cell carcinoma patients

11 July 2018

1 reference

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The role of FAK in tumor metabolism and therapy.

11 July 2018

1 reference

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In vivo imaging of glucose uptake and metabolism in tumors

11 July 2018

1 reference

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Mitochondrial complex I activity and NAD /NADH balance regulate breast cancer progression.

11 July 2018

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RHOA-FAK is a required signaling axis for the maintenance of KRAS-driven lung adenocarcinomas

11 July 2018

1 reference

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Inhibition of focal adhesion kinase (FAK) activity prevents anchorage-independent ovarian carcinoma cell growth and tumor progression.

11 July 2018

1 reference

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Inhibiting the interaction of cMET and IGF-1R with FAK effectively reduces growth of pancreatic cancer cells in vitro and in vivo

11 July 2018

1 reference

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Hyperpolarized 13C-pyruvate magnetic resonance reveals rapid lactate export in metastatic renal cell carcinomas

11 July 2018

1 reference

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α-Enolase, a multifunctional protein: its role on pathophysiological situations

11 July 2018

1 reference

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BTG2 suppresses cancer cell migration through inhibition of Src-FAK signaling by downregulation of reactive oxygen species generation in mitochondria

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486081

The role of focal adhesion kinase catalytic activity on the proliferation and migration of squamous cell carcinoma cells

11 July 2018

1 reference

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Clinical importance and potential use of small molecule inhibitors of focal adhesion kinase

11 July 2018

1 reference

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Caveolin-1 and integrin β1 regulate embryonic stem cell proliferation via p38 MAPK and FAK in high glucose

11 July 2018

1 reference

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DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors

11 July 2018

1 reference

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The FERM domain: organizing the structure and function of FAK.

11 July 2018

1 reference

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A novel strategy to inhibit FAK and IGF-1R decreases growth of pancreatic cancer xenografts

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486081

Targeting of the protein interaction site between FAK and IGF-1R.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486081

Focal adhesion kinase (FAK) activates and stabilizes IGF-1 receptor

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486081

Antixenograft tumor activity of a humanized anti-insulin-like growth factor-I receptor monoclonal antibody is associated with decreased AKT activation and glucose uptake.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486081

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

11 July 2018

1 reference

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Pyruvate kinase M2 is a phosphotyrosine-binding protein

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486081

Inactivation of focal adhesion kinase in cardiomyocytes promotes eccentric cardiac hypertrophy and fibrosis in mice

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486081

Overexpression of FAK promotes Ras activity through the formation of a FAK/p120RasGAP complex in malignant astrocytoma cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486081

The effect of elevated extracellular glucose on adherens junction proteins in cultured rat heart endothelial cells

11 July 2018

1 reference

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Dominant-negative hypoxia-inducible factor-1 alpha reduces tumorigenicity of pancreatic cancer cells through the suppression of glucose metabolism

11 July 2018

1 reference

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Cross talk of pp125(FAK) and pp59(Lyn) non-receptor tyrosine kinases to insulin-mimetic signaling in adipocytes

11 July 2018

1 reference

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Role of focal adhesion kinase in MAP kinase activation by insulin-like growth factor-I or insulin

11 July 2018

1 reference

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A role for focal adhesion kinase in cardiac mitochondrial biogenesis induced by mechanical stress

11 July 2018

1 reference

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Endothelial cell-laminin interaction: modulation of LDH expression involves alpha6beta4 integrin-FAK-p38MAPK pathway

25 September 2018

1 reference

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Insulin-mimetic signaling by the sulfonylurea glimepiride and phosphoinositolglycans involves distinct mechanisms for redistribution of lipid raft components

25 September 2018

1 reference

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Circulating Autoantibodies to Phosphorylated α-Enolase are a Hallmark of Pancreatic Cancer

25 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038/ONC.2015.256

Focal adhesion kinase expressed by nerve cell lines shows increased tyrosine phosphorylation in response to Alzheimer's A beta peptide

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26119934

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Expression of glycolytic enzymes is increased in pancreatic cancerous tissues as evidenced by proteomic profiling by two-dimensional electrophoresis and liquid chromatography-mass spectrometry/mass spectrometry

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26119934

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2015.256

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26119934 AND SRC:MED&resulttype=core&format=json

14 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26119934 AND SRC:MED&resulttype=core&format=json

14 June 2020

PubMed publication ID

26119934

1 reference