Regulation by a chaperone improves substrate selectivity during cotranslational protein targeting (Q35795958)

26056263

10 August 2017

title

Regulation by a chaperone improves substrate selectivity during cotranslational protein targeting (English)

1 reference

10 August 2017

0 references

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26056263 AND SRC:MED&resulttype=core&format=json

13 June 2020

Ishu Saraogi

4

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13 June 2020

author name string

Aileen Ariosa

1

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13 June 2020

Jae Ho Lee

2

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13 June 2020

Shu-ou Shan

5

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13 June 2020

language of work or name

English

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publication date

8 June 2015

1 reference

26056263

Proceedings of the National Academy of Sciences of the United States of America

10 August 2017

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26056263 AND SRC:MED&resulttype=core&format=json

13 June 2020

volume

112

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13 June 2020

issue

25

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13 June 2020

page(s)

E3169-78

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A structural model of the active ribosome-bound membrane protein insertase YidC

13 June 2020

cites work

1 reference

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Structure of the Mammalian Ribosome-Sec61 Complex to 3.4 Å Resolution

27 July 2018

1 reference

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Regulation of cargo recognition, commitment, and unloading drives cotranslational protein targeting

27 July 2018

1 reference

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Signal recognition particle-ribosome binding is sensitive to nascent chain length

27 July 2018

1 reference

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Membrane protein insertion and proton-motive-force-dependent secretion through the bacterial holo-translocon SecYEG-SecDF-YajC-YidC.

27 July 2018

1 reference

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Structures of the Sec61 complex engaged in nascent peptide translocation or membrane insertion

27 July 2018

1 reference

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Structure of the SecY channel during initiation of protein translocation

27 July 2018

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Structural basis of signal sequence surveillance and selection by the SRP–FtsY complex

27 July 2018

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Cdc48-associated complex bound to 60S particles is required for the clearance of aberrant translation products

27 July 2018

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Quality control systems for aberrant mRNAs induced by aberrant translation elongation and termination

27 July 2018

1 reference

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Structural characterization of a eukaryotic chaperone--the ribosome-associated complex

27 July 2018

1 reference

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A ribosome-bound quality control complex triggers degradation of nascent peptides and signals translation stress

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Selective ribosome profiling reveals the cotranslational chaperone action of trigger factor in vivo

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Cryo-electron microscopy of ribosomal complexes in cotranslational folding, targeting, and translocation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Defining the specificity of cotranslationally acting chaperones by systematic analysis of mRNAs associated with ribosome-nascent chain complexes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Cryo-EM structure of the ribosome–SecYE complex in the membrane environment

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Protein Folding at the Exit Tunnel

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Molecular mechanism of co-translational protein targeting by the signal recognition particle

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Cryo-EM structure of the E. coli translating ribosome in complex with SRP and its receptor

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Role of a ribosome-associated E3 ubiquitin ligase in protein quality control

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Sequential checkpoints govern substrate selection during cotranslational protein targeting

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

The ribosome as a platform for co-translational processing, folding and targeting of newly synthesized proteins

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

YidC and Oxa1 form dimeric insertion pores on the translating ribosome

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Multiple conformational switches in a GTPase complex control co-translational protein targeting

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Demonstration of a multistep mechanism for assembly of the SRP x SRP receptor complex: implications for the catalytic role of SRP RNA.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Molecular mechanism and structure of Trigger Factor bound to the translating ribosome

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

A peptide deformylase-ribosome complex reveals mechanism of nascent chain processing

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Conformational changes in the GTPase modules of the signal reception particle and its receptor drive initiation of protein translocation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Generation of ribosome nascent chain complexes for structural and functional studies

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Identification of nascent chain interaction sites on trigger factor

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Structure of the E. coli signal recognition particle bound to a translating ribosome.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Following the signal sequence from ribosomal tunnel exit to signal recognition particle

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Sequence-specific interactions of nascent Escherichia coli polypeptides with trigger factor and signal recognition particle

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Structure of the E. coli protein-conducting channel bound to a translating ribosome

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

An unusual signal peptide facilitates late steps in the biogenesis of a bacterial autotransporter

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Functional dissection of Escherichia coli trigger factor: unraveling the function of individual domains

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Trigger factor binds to ribosome-signal-recognition particle (SRP) complexes and is excluded by binding of the SRP receptor

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Interplay of signal recognition particle and trigger factor at L23 near the nascent chain exit site on the Escherichia coli ribosome

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Assembly and overexpression of membrane proteins in Escherichia coli

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

SRP-dependent co-translational targeting and SecA-dependent translocation analyzed as individual steps in the export of a bacterial protein

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Discrimination between SRP- and SecA/SecB-dependent substrates involves selective recognition of nascent chains by SRP and trigger factor

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

The Escherichia coli SRP and SecB targeting pathways converge at the translocon

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Co-translational protein targeting catalyzed by the Escherichia coli signal recognition particle and its receptor

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Early events in preprotein recognition in E. coli: interaction of SRP and trigger factor with nascent polypeptides.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

The affinity of signal recognition particle for presecretory proteins is dependent on nascent chain length

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Cdc48/p97 promotes degradation of aberrant nascent polypeptides bound to the ribosome

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Dynamic switch of the signal recognition particle from scanning to targeting.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Site-specific fluorescent labeling of nascent proteins on the translating ribosome.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

SecA interacts with ribosomes in order to facilitate posttranslational translocation in bacteria.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Lipid activation of the signal recognition particle receptor provides spatial coordination of protein targeting

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Real-time observation of trigger factor function on translating ribosomes.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

An unusual signal peptide extension inhibits the binding of bacterial presecretory proteins to the signal recognition particle, trigger factor, and the SecYEG complex

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

The binding mode of the trigger factor on the ribosome: implications for protein folding and SRP interaction.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Trigger factor in complex with the ribosome forms a molecular cradle for nascent proteins.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Simultaneous binding of trigger factor and signal recognition particle to the E. coli ribosome.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Heterodimeric GTPase Core of the SRP Targeting Complex

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Substrate twinning activates the signal recognition particle and its receptor

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Signal recognition particle binds to ribosome-bound signal sequences with fluorescence-detected subnanomolar affinity that does not diminish as the nascent chain lengthens.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Interaction of trigger factor with the ribosome

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

L23 protein functions as a chaperone docking site on the ribosome

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Trigger factor retards protein export in Escherichia coli.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

YidC and SecY mediate membrane insertion of a Type I transmembrane domain.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Role of SRP RNA in the GTPase cycles of Ffh and FtsY.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Architecture of the protein-conducting channel associated with the translating 80S ribosome

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Trigger factor and DnaK cooperate in folding of newly synthesized proteins.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

In vitro studies with purified components reveal signal recognition particle (SRP) and SecA/SecB as constituents of two independent protein-targeting pathways of Escherichia coli

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

The nascent polypeptide-associated complex modulates interactions between the signal recognition particle and the ribosome

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Translocation of proteins across the endoplasmic reticulum III. Signal recognition protein (SRP) causes signal sequence-dependent and site-specific arrest of chain elongation that is released by microsomal membranes

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

The "trigger factor cycle" includes ribosomes, presecretory proteins, and the plasma membrane

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485088

Signal recognition particle: an essential protein-targeting machine

25 September 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.1422863112

Direct visualization reveals dynamics of a transient intermediate during protein assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.1422863112

Fidelity of cotranslational protein targeting by the signal recognition particle

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.1422863112

Synergistic actions between the SRP RNA and translating ribosome allow efficient delivery of the correct cargos during cotranslational protein targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.1422863112

Translation elongation regulates substrate selection by the signal recognition particle

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.1422863112

Nascent membrane and presecretory proteins synthesized in Escherichia coli associate with signal recognition particle and trigger factor

21 January 2018

1 reference

12 December 2020

Alternate recruitment of signal recognition particle and trigger factor to the signal sequence of a growing nascent polypeptide

1 reference

12 December 2020

Dynamics of trigger factor interaction with translating ribosomes

1 reference

12 December 2020

Interplay between trigger factor and other protein biogenesis factors on the ribosome

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1422863112

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26056263 AND SRC:MED&resulttype=core&format=json

13 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26056263 AND SRC:MED&resulttype=core&format=json

13 June 2020

26056263

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26056263 AND SRC:MED&resulttype=core&format=json