Retinoids and TRAIL: two cooperating actors to fight against cancer (Q35756905)

10 August 2017

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title

Retinoids and TRAIL: two cooperating actors to fight against cancer (English)

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10 August 2017

Hinrich Gronemeyer

2

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Lucia Altucci

object named as

Lucia Altucci

series ordinal

1

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language of work or name

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1 January 2004

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10 August 2017

published in

Vitamins and Hormones

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10 August 2017

volume

67

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10 August 2017

page(s)

319-345

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Apo2L/TRAIL: apoptosis signaling, biology, and potential for cancer therapy

10 August 2017

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RAR-independent RXR signaling induces t(15;17) leukemia cell maturation

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Cysteine 230 is essential for the structure and activity of the cytotoxic ligand TRAIL

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RAR-specific agonist/antagonists which dissociate transactivation and AP1 transrepression inhibit anchorage-independent cell proliferation.

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An essential role for retinoid receptors RARbeta and RXRgamma in long-term potentiation and depression

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The role of vitamin A in mammalian reproduction and embryonic development

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Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice

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Docosahexaenoic acid, a ligand for the retinoid X receptor in mouse brain

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The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain

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Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family

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Ligand-dependent occupancy of the retinoic acid receptor beta 2 promoter in vivo

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Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor

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7 January 2021

ATP-driven chromatin remodeling activity and histone acetyltransferases act sequentially during transactivation by RAR/RXR In vitro

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7 January 2021

Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells

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7 January 2021

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

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7 January 2021

Bexarotene is effective and safe for treatment of refractory advanced-stage cutaneous T-cell lymphoma: multinational phase II-III trial results

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7 January 2021

A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein

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7 January 2021

DIABLO promotes apoptosis by removing MIHA/XIAP from processed caspase 9

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7 January 2021

Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL.

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7 January 2021

Multicenter phase II study of oral bexarotene for patients with metastatic breast cancer

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7 January 2021

All-trans retinoic acid and chemotherapy in the treatment of acute promyelocytic leukemia

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7 January 2021

The TRAIL to selective tumor death

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7 January 2021

ArRAnging the hindbrain

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7 January 2021

Co-regulator recruitment and the mechanism of retinoic acid receptor synergy

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7 January 2021

Transcriptional cross-talk, the second mode of steroid hormone receptor action

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7 January 2021

Two oncogenes, v-fos and v-ras, cooperate to convert normal keratinocytes to squamous cell carcinoma

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7 January 2021

Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia

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7 January 2021

Formation of PML/RAR alpha high molecular weight nuclear complexes through the PML coiled-coil region is essential for the PML/RAR alpha-mediated retinoic acid response

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7 January 2021

The function of PML in p53-dependent apoptosis

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Distinct interactions of PML-RARalpha and PLZF-RARalpha with co-repressors determine differential responses to RA in APL.

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Induction of apoptosis in ovarian carcinoma cells by AHPN/CD437 is mediated by retinoic acid receptors

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7 January 2021

The cysteine-rich regions of the regulatory domains of Raf and protein kinase C as retinoid receptors

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7 January 2021

Triggering cell death: the crystal structure of Apo2L/TRAIL in a complex with death receptor 5

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7 January 2021

A unique zinc-binding site revealed by a high-resolution X-ray structure of homotrimeric Apo2L/TRAIL

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7 January 2021

Selective ablation of retinoid X receptor alpha in hepatocytes impairs their lifespan and regenerative capacity

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7 January 2021

Retinoids as ligands and coactivators of protein kinase C alpha

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7 January 2021

Inhibition of death receptor signals by cellular FLIP

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7 January 2021

The TRAP/SMCC/Mediator complex and thyroid hormone receptor function

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7 January 2021

Combinatorial roles of the nuclear receptor corepressor in transcription and development

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7 January 2021

Nonsteroid nuclear receptors: what are genetic studies telling us about their role in real life?

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7 January 2021

Abnormal spermatogenesis in RXR beta mutant mice.

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7 January 2021

Bexarotene is a new treatment option for lymphomatoid papulosis

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7 January 2021

Impaired locomotion and dopamine signaling in retinoid receptor mutant mice

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7 January 2021

Role of promyelocytic leukemia (PML) sumolation in nuclear body formation, 11S proteasome recruitment, and As2O3-induced PML or PML/retinoic acid receptor alpha degradation

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7 January 2021

Apo2L/TRAIL and its death and decoy receptors

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7 January 2021

v-Ha-ras transgene abrogates the initiation step in mouse skin tumorigenesis: effects of phorbol esters and retinoic acid

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7 January 2021

Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3.

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7 January 2021

Skin abnormalities generated by temporally controlled RXRalpha mutations in mouse epidermis

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7 January 2021

Orphan receptor COUP-TF is required for induction of retinoic acid receptor beta, growth inhibition, and apoptosis by retinoic acid in cancer cells

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7 January 2021

Acquisition of oncogenic potential by RAR chimeras in acute promyelocytic leukemia through formation of homodimers.

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7 January 2021

Role of the histone deacetylase complex in acute promyelocytic leukaemia

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7 January 2021

Ribozyme targeting demonstrates that the nuclear receptor coactivator AIB1 is a rate-limiting factor for estrogen-dependent growth of human MCF-7 breast cancer cells.

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7 January 2021

Activation of the phosphatidylinositol 3-kinase/Akt signaling pathway by retinoic acid is required for neural differentiation of SH-SY5Y human neuroblastoma cells

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7 January 2021

Regulation of interferon and retinoic acid-induced cell death activation through thioredoxin reductase

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7 January 2021

Identification and Molecular Cloning of Two Novel Receptors for the Cytotoxic Ligand TRAIL

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7 January 2021

Retinoid signalling in the development of the central nervous system

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7 January 2021

A novel receptor for Apo2L/TRAIL contains a truncated death domain

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7 January 2021

Retinoids, alveolus formation, and alveolar deficiency: clinical implications

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7 January 2021

Combinatorial control of gene expression by nuclear receptors and coregulators

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7 January 2021

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7 January 2021

Site- and time-specific gene targeting in the mouse

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7 January 2021

Oligomerization of RAR and AML1 transcription factors as a novel mechanism of oncogenic activation.

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7 January 2021

Vitamin A deprivation results in reversible loss of hippocampal long-term synaptic plasticity

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7 January 2021

Structure of the TRAIL-DR5 complex reveals mechanisms conferring specificity in apoptotic initiation

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7 January 2021

Activation of retinoid X receptors induces apoptosis in HL-60 cell lines

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7 January 2021

An Antagonist Decoy Receptor and a Death Domain-Containing Receptor for TRAIL

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7 January 2021

The receptor for the cytotoxic ligand TRAIL

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7 January 2021

Oncogenes and tumor suppressors in the molecular pathogenesis of acute promyelocytic leukemia

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7 January 2021

Atmospheric carbon dioxide concentrations over the past 60 million years

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7 January 2021

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7 January 2021

Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family

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7 January 2021

Mediator complexes and transcription.

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7 January 2021

Cyclic, proteasome-mediated turnover of unliganded and liganded ERalpha on responsive promoters is an integral feature of estrogen signaling

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7 January 2021

Therapeutic potential of selective modulators of nuclear receptor action

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7 January 2021

Nuclear receptors: integration of multiple signalling pathways through phosphorylation

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Alternate surfaces of transcriptional coregulator GRIP1 function in different glucocorticoid receptor activation and repression contexts

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7 January 2021

Induction of Egr-1 expression by the retinoid AHPN in human lung carcinoma cells is dependent on activated ERK1/2.

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7 January 2021

The role of PML in tumor suppression

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7 January 2021

TRICK2, a new alternatively spliced receptor that transduces the cytotoxic signal from TRAIL

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7 January 2021

Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription

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7 January 2021

Formation of the androgen receptor transcription complex

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7 January 2021

Control of TRAIL-Induced Apoptosis by a Family of Signaling and Decoy Receptors

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7 January 2021

Osteoprotegerin: a novel secreted protein involved in the regulation of bone density

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7 January 2021

Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development

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7 January 2021

Disruption of differentiation in human cancer: AML shows the way.

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7 January 2021

Temperature-sensitive differential affinity of TRAIL for its receptors. DR5 is the highest affinity receptor

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7 January 2021

All-trans retinoic acid induces differentiation of ducts and endocrine cells by mesenchymal/epithelial interactions in embryonic pancreas.

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7 January 2021

TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL.

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7 January 2021

Retinoic acid regulates aberrant nuclear localization of PML-RAR alpha in acute promyelocytic leukemia cells

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7 January 2021

Methylation and silencing of the retinoic acid receptor-beta2 gene in breast cancer.

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7 January 2021

Identification and characterization of a new member of the TNF family that induces apoptosis

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7 January 2021

Transcriptional silencing is defined by isoform- and heterodimer-specific interactions between nuclear hormone receptors and corepressors

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7 January 2021

The transcriptional role of PML and the nuclear body

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7 January 2021

10.1016/S0083-6729(04)67017-8

Identifiers

DOI

1 reference

release_e2hot2k2uzgylarf6yllaufmc4

10 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/e2hot2k2uzgylarf6yllaufmc4

24 November 2022

mapped directly with Wikidata item

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