Modulation of TRAIL signaling for cancer therapy (Q35756898)

10 August 2017

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title

Modulation of TRAIL signaling for cancer therapy (English)

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10 August 2017

author

Klaus-Michael Debatin

series ordinal

2

object named as

Klaus-Michael Debatin

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Simone Fulda

series ordinal

1

object named as

Simone Fulda

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publication date

1 January 2004

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10 August 2017

published in

Vitamins and Hormones

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10 August 2017

volume

67

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10 August 2017

page(s)

275-290

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Genomic organization and mutation analyses of the DR5/TRAIL receptor 2 gene in colorectal carcinomas

10 August 2017

cites work

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7 January 2021

Safety and antitumor activity of recombinant soluble Apo2 ligand

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7 January 2021

Disruption of NF-kappaB signaling reveals a novel role for NF-kappaB in the regulation of TNF-related apoptosis-inducing ligand expression

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7 January 2021

Sensitization of resistant lymphoma cells to irradiation-induced apoptosis by the death ligand TRAIL

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7 January 2021

TRAIL receptor-2 signals apoptosis through FADD and caspase-8

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7 January 2021

Death Receptor 5, a New Member of the TNFR Family, and DR4 Induce FADD-Dependent Apoptosis and Activate the NF-κB Pathway

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7 January 2021

Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy

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7 January 2021

Isotype-dependent inhibition of tumor growth in vivo by monoclonal antibodies to death receptor 4

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7 January 2021

Caspase-6 is the direct activator of caspase-8 in the cytochrome c-induced apoptosis pathway: absolute requirement for removal of caspase-6 prodomain

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7 January 2021

Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice

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7 January 2021

Chemotherapy: targeting the mitochondrial cell death pathway

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7 January 2021

The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain

1 reference

https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family

1 reference

https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO.

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7 January 2021

Insights into cancer therapeutic design based on p53 and TRAIL receptor signaling

1 reference

https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL.

1 reference

https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

TRAIL induced survival and proliferation in cancer cells resistant towards TRAIL-induced apoptosis mediated by NF-kappaB.

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7 January 2021

IFNgamma sensitizes for apoptosis by upregulating caspase-8 expression through the Stat1 pathway.

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7 January 2021

Death receptor signaling in cancer therapy

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7 January 2021

Sensitization for death receptor- or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer

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7 January 2021

Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression.

1 reference

https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo

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7 January 2021

Modulation of tumor necrosis factor apoptosis-inducing ligand- induced NF-kappa B activation by inhibition of apical caspases

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7 January 2021

The biochemistry of apoptosis

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https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

Bcl-XL protects pancreatic adenocarcinoma cells against CD95- and TRAIL-receptor-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity.

1 reference

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7 January 2021

Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand

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https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

Apoptosis: a link between cancer genetics and chemotherapy

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https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

Inhibition of NF-kappaB activity enhances TRAIL mediated apoptosis in breast cancer cell lines.

1 reference

https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

An inducible pathway for degradation of FLIP protein sensitizes tumor cells to TRAIL-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.

1 reference

https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8

1 reference

https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

FLICE-inhibitory proteins: regulators of death receptor-mediated apoptosis

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7 January 2021

Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions

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7 January 2021

Apo2L/TRAIL and its death and decoy receptors

1 reference

https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

Somatic mutations of TRAIL-receptor 1 and TRAIL-receptor 2 genes in non-Hodgkin's lymphoma

1 reference

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7 January 2021

https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

1 reference

7 January 2021

Identification and Molecular Cloning of Two Novel Receptors for the Cytotoxic Ligand TRAIL

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https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

Activation of apoptosis by Apo-2 ligand is independent of FADD but blocked by CrmA.

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https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

A novel receptor for Apo2L/TRAIL contains a truncated death domain

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https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

p53-independent upregulation of KILLER/DR5 TRAIL receptor expression by glucocorticoids and interferon-gamma

1 reference

https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

The TRAIL decoy receptor TRUNDD (DcR2, TRAIL-R4) is induced by adenovirus-p53 overexpression and can delay TRAIL-, p53-, and KILLER/DR5-dependent colon cancer apoptosis

1 reference

https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

STAT-1-independent upregulation of FADD and procaspase-3 and -8 in cancer cells treated with cytotoxic drugs.

1 reference

https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

TRAIL (APO-2L) induces apoptosis in human prostate cancer cells that is inhibitable by Bcl-2.

1 reference

https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

Apoptotic DNA fragmentation

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https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

Human brain-cell death induced by tumour-necrosis-factor-related apoptosis-inducing ligand (TRAIL)

1 reference

https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

Sensitization to TRAIL-induced apoptosis and modulation of FLICE-inhibitory protein in B chronic lymphocytic leukemia by actinomycin D.

1 reference

https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

Cell surface Death Receptor signaling in normal and cancer cells

1 reference

https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

An Antagonist Decoy Receptor and a Death Domain-Containing Receptor for TRAIL

1 reference

https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

TRUNDD, a new member of the TRAIL receptor family that antagonizes TRAIL signalling

1 reference

https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

The receptor for the cytotoxic ligand TRAIL

1 reference

https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

Regulation of death receptor expression and TRAIL/Apo2L-induced apoptosis by NF-kappaB

1 reference

https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

CCNU-dependent potentiation of TRAIL/Apo2L-induced apoptosis in human glioma cells is p53-independent but may involve enhanced cytochrome c release

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https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

IAP proteins: blocking the road to death's door

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https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

Apoptosome: the seven-spoked death machine

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https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB

1 reference

https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) contributes to interferon gamma-dependent natural killer cell protection from tumor metastasis

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https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

Nature's TRAIL--on a path to cancer immunotherapy

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https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8.

1 reference

https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

1 reference

https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells

1 reference

https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

Wild-type p53 transactivates the KILLER/DR5 gene through an intronic sequence-specific DNA-binding site.

1 reference

https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

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https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

Apoptosis in the pathogenesis and treatment of disease

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https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

Caspases: enemies within

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https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet.

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https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

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https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL.

1 reference

https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems

1 reference

https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

Identification and characterization of a new member of the TNF family that induces apoptosis

1 reference

https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene

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https://api.crossref.org/works/10.1016/S0083-6729(04)67015-4

7 January 2021

10.1016/S0083-6729(04)67015-4

Identifiers

DOI

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10 August 2017

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