Lens defects and age-related fiber cell degeneration in a mouse model of increased AbetaPP gene dosage in Down syndrome (Q35748237)

10 August 2017

title

Lens defects and age-related fiber cell degeneration in a mouse model of increased AbetaPP gene dosage in Down syndrome (English)

1 reference

10 August 2017

1 reference

Peter H Frederikse

1

1 reference

10 August 2017

Xiao-Ou Ren

series ordinal

2

1 reference

10 August 2017

language of work or name

English

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publication date

1 December 2002

1 reference

The American Journal of Pathology

10 August 2017

published in

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10 August 2017

volume

161

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10 August 2017

issue

6

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10 August 2017

page(s)

1985-1990

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Of replications and refutations: the status of Alzheimer's disease genetic research

10 August 2017

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c-Jun N-terminal kinase (JNK)-interacting protein-1b/islet-brain-1 scaffolds Alzheimer's amyloid precursor protein with JNK

12 July 2018

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Copper and prion disease

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A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

12 July 2018

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Multilamellar bodies as potential scattering particles in human age-related nuclear cataracts

12 July 2018

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Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice.

12 July 2018

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Specific metal-catalysed protein oxidation reactions in chronic degenerative disorders of ageing: focus on Alzheimer's disease and age-related cataracts.

12 July 2018

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Oxidative processes in Alzheimer's disease: the role of abeta-metal interactions

12 July 2018

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Developmental regulation of amyloid precursor protein at the neuromuscular junction in mouse skeletal muscle

12 July 2018

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Notch signaling and the determination of appendage identity

12 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850926

Copper levels are increased in the cerebral cortex and liver of APP and APLP2 knockout mice

12 July 2018

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Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation

12 July 2018

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Notch signaling: cell fate control and signal integration in development

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Molecular mapping of Alzheimer-type dementia in Down's syndrome

12 July 2018

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Amyloid β-protein toxicity and oxidative stress in Alzheimer's disease

12 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850926

Appican expression induces morphological changes in C6 glioma cells and promotes adhesion of neural cells to the extracellular matrix

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850926

Characterization of appican, the chondroitin sulfate proteoglycan form of the Alzheimer amyloid precursor protein

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850926

The alternatively spliced Kunitz protease inhibitor domain alters amyloid beta protein precursor processing and amyloid beta protein production in cultured cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850926

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850926

Expression of the human beta-amyloid precursor protein gene from a yeast artificial chromosome in transgenic mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850926

Regulation and expression of the Alzheimer's beta/A4 amyloid protein precursor in health, disease, and Down's syndrome

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850926

Transgenic mice expressing human beta-APP751, but not mice expressing beta-APP695, display early Alzheimer's disease-like histopathology

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850926

Introduction and expression of the 400 kilobase amyloid precursor protein gene in transgenic mice [corrected]

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850926

A mouse model for Down syndrome exhibits learning and behaviour deficits

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850926

Down's syndrome, aging, and Alzheimer's disease: a clinical review

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850926

Glutathione peroxidase-1 deficiency leads to increased nuclear light scattering, membrane damage, and cataract formation in gene-knockout mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850926

Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850926

Prion protein expression in mammalian lenses.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850926

The Drosophila beta-amyloid precursor protein homolog promotes synapse differentiation at the neuromuscular junction.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850926

Presenilin expression in the ocular lens

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850926

Expression of the APP gene family in brain cells, brain development and aging

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850926

Oxidative stress increases production of beta-amyloid precursor protein and beta-amyloid (Abeta) in mammalian lenses, and Abeta has toxic effects on lens epithelial cells

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850926

Expression of APP in brains of transgenic mice containing the entire human APP gene.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850926

Levels and alternative splicing of amyloid beta protein precursor (APP) transcripts in brains of APP transgenic mice and humans with Alzheimer's disease

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850926

Amyloid protein precursor messenger RNAs: differential expression in Alzheimer's disease.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850926

Presence of soluble amyloid beta-peptide precedes amyloid plaque formation in Down's syndrome

25 September 2018

1 reference

https://api.crossref.org/works/10.1016/S0002-9440(10)64475-6

Ocular findings in Down's syndrome

7 January 2021

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https://api.crossref.org/works/10.1016/S0002-9440(10)64475-6

Genetics of Alzheimer's disease

7 January 2021

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https://api.crossref.org/works/10.1016/S0002-9440(10)64475-6

The expression and function of Notch pathway genes in the developing rat eye

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0002-9440(10)64475-6

Thiamine deficiency in vivo produces fiber cell degeneration in mouse lenses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0002-9440(10)64475-6

Expression of Deltex1 during mouse embryogenesis: comparison with Notch1, 2 and 3 expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0002-9440(10)64475-6

Finger-like projections of plasma membrane in the most senescent fiber cells of human lenses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0002-9440(10)64475-6

The ultrastructure of fiber cells in primate lenses: a model for studying membrane senescence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0002-9440(10)64475-6

10.1016/S0002-9440(10)64475-6

7 January 2021

Identifiers

DOI

1 reference

10 August 2017

1 reference

10 August 2017

1 reference